Principal Research Scientist I Chemistry

Full Job Description

Job Description

AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013, following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader, to develop and market advanced therapies that address some of the world's most complex and serious diseases. AbbVie employs approximately 50,000 people worldwide and markets medicines in more than 170 countries.

AbbVie is seeking a Principal Research Scientist I to conduct process research and development of small molecules from pre-clinical through early clinical phases.

 

Key Responsibilities:

 

We seek a highly motivated scientist, with a proven track record of accomplishment in the biopharmaceutical industry, to work in a cross-functional team environment. The qualified candidate will deliver results in a team-oriented setting.

The successful candidate will be responsible for setting project strategies, defining project responsibilities and timelines, providing leadership in a matrixed team setting and developing robust processes for cGMP manufacturing of AbbVie’s small molecule and/or antibody-drug conjugate candidates.

The successful candidate will conceive of and develop synthetic routes for preclinical (GLP tox) and first in human (FIH) clinical deliveries, develop manufacturing processes, demonstrate processes in the API Pilot Plant, and establish appropriate control strategies.

The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, solid state scientists, drug product development, program management, external partners, etc.  The selected candidate will collaborate with Discovery Teams, Development Sciences Core Teams, and Asset Strategy Teams to advance preclinical and clinical candidates. It is expected that the candidate will utilize their expertise across CMC disciplines to generate collaborations with drug product development and regulatory affairs to further program goals.

The ideal candidate will have strong verbal and written communication skills, and will serve as the lead author on development reports and as a key contributor to regulatory filings.