1 Scientific Leadership jobs in Boston

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By clicking the Apply button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with TakedasPrivacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge.

Objective / Purpose:

• As a Computational Chemistry Leader,you will work as part of a multi-disciplinary team of Medicinal Chemists, Computational Chemists, Data Scientist, Structural Biologists, Pharmacologists and Biologists to provide Computational expertise to advance drug discovery projects

• Contribute to drug discovery efforts across various modalities including small molecules, bifunctional degraders, peptides, RNA/oligonucleotides, and biologics

• Implement and execute innovative computational methodologies and tools such as AI approaches to support drug discovery efforts

Accountabilities:

• Demonstrate expert understanding of computational chemistry principles and their application within a multidisciplinary drug discovery environment

• Identify, develop, validate, and implement innovative computational approaches that improve research productivity and success

• Provide crucial technical knowledge and input to project teams to drive decision-making in drug discovery projects

• Build and develop a strong team of Computational Chemists to high productivity levels

• Demonstrate leadership and enterprise thinking in managing multi-disciplinary team

DIMENSIONS AND ASPECTS:

• Expertise in a variety of computational tools and methodologies including docking, virtual screening, molecular dynamics, free energy perturbation, homology modeling, quantum mechanics, pharmacophore elucidation, data mining, machine learning, cheminformatics, clustering, similarity & diversity analysis

• Significant Industry experience contributing as Computational Chemist on drug discovery projects

• Strong Impact in progressing Discovery Projects from Hits to Clinical Leads

• Extensive knowledge & experience in using a variety of tools for Hit ID

• Provide project teams with computational strategies to inform, influence, and prioritize compound designs for potency/selectivity and improve ADME/Tox endpoints

• Ability to effectively integrate emerging generative chemistry methods and other modern machine learning and artificial intelligence (AI) applications in small molecule drug discovery

• Proficiency with state-of-the-art Computational Chemistry software

• Network with renowned researchers in computational chemistry/AI

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

• PhD degree in a relevant scientific discipline

• 6+ years of Industry (pharma/biotech) drug discovery experience required

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

U.S. Base Salary Range:

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

EEO Statement

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Job Exempt