112 Charles River Laboratories jobs in Wilmington
Senior Pharmaceutical Research Scientist
Posted today
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Job Description
Responsibilities:
- Design, conduct, and interpret complex experiments in drug discovery and development.
- Identify and validate novel drug targets and therapeutic strategies.
- Develop and optimize in vitro and in vivo assays for target engagement and efficacy studies.
- Collaborate with medicinal chemists to guide lead optimization efforts.
- Contribute to the preclinical development of drug candidates, including pharmacology and DMPK studies.
- Analyze experimental data using statistical methods and relevant software.
- Prepare scientific reports, manuscripts for publication, and presentations.
- Stay abreast of scientific literature and emerging technologies in the pharmaceutical industry.
- Mentor and guide junior research scientists.
- Contribute to the strategic planning and execution of research programs.
Qualifications:
- Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related field.
- Minimum of 5 years of relevant postdoctoral or industry research experience in drug discovery.
- Proven expertise in one or more therapeutic areas (e.g., oncology, neuroscience, infectious diseases).
- Extensive experience with various experimental techniques and instrumentation relevant to drug discovery.
- Strong understanding of drug development processes from discovery to preclinical stages.
- Excellent analytical, problem-solving, and data interpretation skills.
- Strong written and verbal communication skills, with a record of scientific publications.
- Ability to work independently and collaboratively in a fast-paced research environment.
Senior Pharmaceutical Research Scientist
Posted today
Job Viewed
Job Description
Responsibilities:
- Design and conduct biological assays for drug discovery.
- Characterize the efficacy and mechanism of action of drug candidates.
- Analyze experimental data and interpret results.
- Contribute to the development of preclinical study designs.
- Collaborate with cross-functional research teams.
- Maintain detailed laboratory notebooks and documentation.
- Present research findings at internal meetings and scientific conferences.
- Stay updated on relevant scientific literature and trends.
- Contribute to patent applications and publications.
- Ph.D. in Biology, Biochemistry, Pharmacology, or a related life science discipline.
- 5+ years of postdoctoral or industry research experience in drug discovery.
- Demonstrated expertise in molecular and cell biology techniques.
- Experience with relevant therapeutic areas is a plus.
- Strong analytical and problem-solving skills.
- Excellent communication and presentation skills.
- Ability to work independently and collaboratively.
Senior Pharmaceutical Research Scientist
Posted today
Job Viewed
Job Description
Key Responsibilities include:
- Designing and executing complex research experiments in areas such as medicinal chemistry, pharmacology, or drug metabolism and pharmacokinetics (DMPK).
- Identifying and validating novel drug targets for a range of therapeutic areas.
- Synthesizing and characterizing potential drug candidates, evaluating their efficacy, safety, and pharmacokinetic properties.
- Utilizing advanced analytical techniques and instrumentation for compound analysis and characterization.
- Interpreting experimental data, drawing meaningful conclusions, and contributing to scientific publications and patent applications.
- Collaborating closely with cross-functional teams, including biology, toxicology, and clinical development, to advance drug candidates through the pipeline.
- Managing research projects, ensuring adherence to timelines, budgets, and quality standards.
- Staying abreast of the latest scientific advancements, literature, and technologies in pharmaceutical research.
- Mentoring junior research scientists and providing technical guidance.
- Preparing technical reports, presentations, and contributing to regulatory submissions.
- Ensuring compliance with all laboratory safety regulations and ethical guidelines.
Qualifications:
- Ph.D. in Medicinal Chemistry, Pharmacology, Biochemistry, or a related life sciences field.
- Minimum of 7 years of relevant post-doctoral or industry experience in pharmaceutical R&D.
- Proven track record in drug discovery, with hands-on experience in experimental design, execution, and data analysis.
- Expertise in specific therapeutic areas or drug discovery platforms is highly desirable.
- Proficiency in modern laboratory techniques and instrumentation relevant to drug discovery.
- Strong understanding of PK/PD principles, drug metabolism, and toxicity assessment.
- Excellent critical thinking, problem-solving, and analytical skills.
- Outstanding written and oral communication skills, with a strong publication record.
- Ability to work independently and collaboratively in a fast-paced research environment.
Senior Pharmaceutical Research Scientist
Posted 2 days ago
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Remote Pharmaceutical Research Scientist
Posted 3 days ago
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Principal Pharmaceutical Research Scientist
Posted 4 days ago
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Job Description
Key Responsibilities:
- Lead independent research programs focused on identifying and validating novel drug targets.
- Design and execute in vitro and in vivo experiments to assess the efficacy and safety of drug candidates.
- Analyze complex biological data, interpret results, and draw meaningful conclusions.
- Develop and optimize experimental assays and methodologies.
- Contribute to the preparation of regulatory submissions (e.g., IND applications).
- Collaborate with cross-functional teams, including medicinal chemistry, DMPK, toxicology, and clinical development.
- Mentor and guide junior scientists and research associates.
- Present research findings at internal meetings and external scientific conferences.
- Stay abreast of the latest scientific literature and advancements in relevant therapeutic areas.
- Contribute to the company's intellectual property portfolio through patent filings.
- Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline.
- 8+ years of relevant postdoctoral and/or industry experience in drug discovery and development.
- Proven expertise in a specific therapeutic area (e.g., oncology, neuroscience, infectious diseases).
- Demonstrated track record of successful research, including peer-reviewed publications and conference presentations.
- Experience with preclinical models and state-of-the-art research technologies.
- Strong understanding of drug development processes from target identification to clinical trials.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional leadership, communication, and interpersonal skills.
- Experience managing research projects and mentoring scientific staff.
- Familiarity with the pharmaceutical landscape in Boston, Massachusetts, US is a plus.
Lead Pharmaceutical Research Scientist
Posted 4 days ago
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Job Description
- Leading discovery research projects from target identification through to preclinical candidate selection.
- Designing and implementing in vitro and in vivo experimental models.
- Developing and optimizing biochemical and cell-based assays.
- Analyzing and interpreting complex datasets, drawing robust conclusions.
- Providing scientific leadership and mentorship to junior research staff.
- Collaborating with internal teams (e.g., medicinal chemistry, DMPK) and external partners.
- Presenting research findings at internal meetings and external scientific conferences.
- Contributing to the preparation of regulatory submission documents.
- Ensuring adherence to laboratory safety protocols and GxP guidelines.
- Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a closely related field.
- A minimum of 6 years of post-doctoral research experience in the pharmaceutical industry.
- Demonstrated success in leading drug discovery projects and achieving research milestones.
- Expertise in relevant therapeutic areas and target classes.
- Proficiency in modern molecular and cellular biology techniques.
- Strong understanding of drug development processes.
- Excellent written and verbal communication skills, including presentation abilities.
- Proven ability to manage projects and mentor scientific staff.
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Principal Pharmaceutical Research Scientist
Posted 4 days ago
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Job Description
Key Responsibilities:
- Design and execute complex research projects aimed at identifying and validating new drug targets and therapeutic modalities.
- Lead experimental design, data interpretation, and troubleshooting for early-stage drug discovery programs.
- Develop and optimize robust biological assays for screening and characterization of small molecules and biologics.
- Conduct in vitro and in vivo studies to assess drug efficacy, pharmacokinetics, and pharmacodynamics.
- Analyze and interpret complex datasets using statistical software and bioinformatics tools.
- Collaborate effectively with cross-functional teams, including medicinal chemistry, DMPK, toxicology, and clinical development.
- Author and contribute to scientific publications, patents, and regulatory submissions.
- Mentor and guide junior research scientists, fostering a culture of scientific excellence and innovation.
- Stay abreast of the latest scientific literature, emerging technologies, and industry trends in pharmaceutical research.
- Present research findings at internal meetings and external scientific conferences.
Qualifications:
- Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
- Minimum of 10 years of post-doctoral and industry research experience in pharmaceutical or biotechnology drug discovery.
- Proven track record of leading successful drug discovery projects and contributing to IND filings.
- Extensive experience in assay development, high-throughput screening (HTS), and cellular/molecular biology techniques.
- Deep understanding of target validation, lead optimization, and preclinical development processes.
- Expertise in relevant therapeutic areas and disease mechanisms is highly desirable.
- Excellent scientific writing and presentation skills.
- Strong leadership, mentorship, and team collaboration abilities.
- Experience with statistical analysis software and data management is required.
Pharmaceutical Research Scientist (Oncology)
Posted 10 days ago
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Senior Pharmaceutical Research Scientist
Posted 10 days ago
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Job Description
The ideal candidate will possess a Ph.D. in a relevant scientific discipline (e.g., Pharmacology, Biochemistry, Molecular Biology) with a proven track record of impactful research publications and a strong background in preclinical drug development. You will be responsible for designing and conducting in vitro and in vivo experiments, analyzing complex data sets, and interpreting results to guide research strategy. Excellent analytical, problem-solving, and communication skills are essential, as is the ability to work effectively in a highly collaborative and fast-paced scientific environment. This position offers the opportunity to work with state-of-the-art technology and contribute to the development of novel therapeutics.
Key responsibilities include:
- Designing, executing, and analyzing complex preclinical research studies for novel drug candidates.
- Developing and validating innovative experimental assays and models.
- Investigating mechanisms of action and potential therapeutic targets.
- Analyzing and interpreting complex biological and pharmacological data.
- Preparing detailed research reports, presentations, and manuscripts for publication.
- Mentoring and guiding junior research scientists and technicians.
- Collaborating with medicinal chemists, pharmacologists, and toxicologists.
- Presenting research findings at internal meetings and external scientific conferences.
- Ensuring compliance with all laboratory safety regulations and protocols.
- Contributing to the development of research strategies and project planning.
- Keeping abreast of the latest scientific literature and technological advancements in the field.
Qualifications required:
- Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline.
- Minimum of 5 years of postdoctoral or industry experience in pharmaceutical research and development.
- Proven track record of impactful research, demonstrated by high-quality publications and presentations.
- Extensive experience in relevant experimental techniques (e.g., cell culture, molecular biology assays, animal models).
- Strong understanding of drug discovery and preclinical development processes.
- Excellent analytical, critical thinking, and problem-solving skills.
- Proficiency in data analysis software and statistical methods.
- Exceptional written and verbal communication skills.
- Ability to work independently and collaboratively in a team-oriented environment.
- Experience with immunotherapy or specific therapeutic areas is a plus.
- Proficiency in laboratory management and record-keeping.
This is an exciting opportunity for a seasoned scientist to join a world-class research organization and contribute to the development of life-changing medicines in Boston, Massachusetts, US .