Principal Pharmaceutical Research Scientist

02108 Boston, Massachusetts $150000 Annually WhatJobs

Posted 4 days ago

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full-time
Our client, a leading biopharmaceutical company, is seeking an accomplished Principal Pharmaceutical Research Scientist to drive innovative drug discovery and development initiatives in Boston, Massachusetts, US . This senior-level position is crucial for leading cutting-edge research projects, from conceptualization through preclinical development. You will be instrumental in designing and executing complex experiments, analyzing data, and contributing to the intellectual property portfolio. The ideal candidate possesses a strong scientific background, a deep understanding of drug development processes, and a proven ability to lead research teams.

Core responsibilities:
  • Leading independent research programs focused on identifying and validating novel therapeutic targets.
  • Designing, optimizing, and executing in vitro and in vivo experiments to assess drug efficacy and safety.
  • Interpreting complex biological data, drawing meaningful conclusions, and recommending strategic directions.
  • Mentoring and guiding junior scientists, fostering a collaborative and high-performance research environment.
  • Authoring scientific publications, patent applications, and regulatory submissions.
  • Collaborating with cross-functional teams, including medicinal chemistry, pharmacology, and clinical development.
  • Presenting research findings at internal meetings and external scientific conferences.
  • Managing research budgets and ensuring the efficient use of resources.
  • Staying abreast of the latest scientific advancements and technological innovations in the pharmaceutical industry.
A Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline is required, along with a minimum of 8 years of relevant industry experience, including a significant track record in drug discovery. Demonstrated experience in leading research projects and managing scientific staff is essential. Expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is a plus. This hybrid role requires a commitment to on-site laboratory work and collaborative in-person meetings, balanced with the flexibility for remote data analysis and strategic planning. Join a world-class team dedicated to developing life-changing medicines in the vibrant biotech hub of Boston, Massachusetts, US .
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Senior Pharmaceutical Research Scientist

02108 Boston, Massachusetts $130000 Annually WhatJobs

Posted 4 days ago

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full-time
Our client, a globally recognized pharmaceutical leader, is seeking a highly motivated and experienced Senior Pharmaceutical Research Scientist to join their innovative drug discovery team in Boston, Massachusetts, US . This hybrid role offers a dynamic work environment, combining essential lab-based research with strategic planning and data analysis conducted remotely. The successful candidate will play a crucial role in designing, executing, and analyzing complex experiments to identify and validate novel therapeutic targets and develop new drug candidates. Expertise in molecular biology, biochemistry, pharmacology, or a related field is essential. You will be responsible for leading research projects, mentoring junior scientists, troubleshooting experimental challenges, and contributing to the interpretation of scientific data. Collaboration with cross-functional teams, including medicinal chemists, computational biologists, and clinical development experts, will be vital. The ability to critically evaluate scientific literature, design robust experimental protocols, and communicate findings effectively through presentations and publications is expected. This position requires a deep understanding of the drug discovery process and a commitment to advancing scientific knowledge for patient benefit.

Key Responsibilities:
  • Design, execute, and analyze complex experiments in drug discovery and development.
  • Identify and validate novel therapeutic targets and drug candidates.
  • Develop and optimize in vitro and in vivo assays.
  • Interpret scientific data, draw conclusions, and make recommendations for future research directions.
  • Lead research projects and provide scientific guidance to junior team members.
  • Troubleshoot experimental issues and propose solutions.
  • Collaborate effectively with cross-functional research and development teams.
  • Prepare and present research findings at internal meetings and external conferences.
  • Contribute to the writing of patents, publications, and regulatory documents.
  • Stay current with scientific literature and emerging technologies in the pharmaceutical field.
Qualifications:
  • Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a closely related discipline.
  • Minimum of 5 years of post-doctoral or industry research experience in pharmaceutical R&D.
  • Proven expertise in drug discovery methodologies and therapeutic areas.
  • Strong hands-on experience with relevant laboratory techniques and instrumentation.
  • Demonstrated ability to design and execute complex experiments and interpret results.
  • Excellent analytical, problem-solving, and critical thinking skills.
  • Strong written and verbal communication skills, including experience presenting scientific data.
  • Experience mentoring junior scientists is highly desirable.
  • Familiarity with biostatistics and data analysis software.
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Senior Pharmaceutical Research Scientist

02108 Boston, Massachusetts $130000 Annually WhatJobs

Posted 4 days ago

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Job Description

full-time
Our client, a leading biopharmaceutical company in Boston, Massachusetts, US , is seeking a highly accomplished Senior Pharmaceutical Research Scientist to drive innovation in drug discovery and development. This critical role involves leading research projects, designing and executing experiments, and contributing to the advancement of novel therapeutic agents. The ideal candidate will possess a strong background in medicinal chemistry, pharmacology, or a related life science discipline, coupled with extensive experience in drug development pipelines. You will play a key role in identifying new targets, synthesizing potential drug candidates, and evaluating their efficacy and safety profiles.

Key Responsibilities:
  • Lead and manage research projects focused on the discovery and development of new pharmaceutical compounds.
  • Design, optimize, and execute in vitro and in vivo experiments to assess drug candidate properties.
  • Synthesize and characterize small molecules using advanced organic chemistry techniques.
  • Collaborate closely with cross-functional teams, including biologists, toxicologists, and clinical researchers.
  • Analyze experimental data, interpret results, and draw conclusions to guide research direction.
  • Prepare technical reports, presentations, and publications to disseminate research findings.
  • Contribute to the development of research strategies and project planning.
  • Stay abreast of the latest scientific literature, technological advancements, and industry trends in pharmaceutical research.
  • Ensure compliance with all relevant laboratory safety protocols and regulatory guidelines.
  • Mentor junior scientists and provide technical guidance within the research team.
  • Contribute to intellectual property development through patent filings.
  • Troubleshoot experimental challenges and develop innovative solutions.
A Ph.D. in Medicinal Chemistry, Organic Chemistry, Pharmacology, Biochemistry, or a related field is required. A minimum of 5 years of post-doctoral or industry research experience in pharmaceutical R&D is essential. Demonstrated expertise in drug discovery, lead optimization, and preclinical development is mandatory. Proven experience with synthetic organic chemistry, analytical techniques (e.g., HPLC, NMR, MS), and in vitro/in vivo assay development is highly desirable. Excellent written and verbal communication skills, with a track record of scientific publications and presentations, are crucial. Strong problem-solving abilities and the capacity to work independently and collaboratively in a fast-paced research environment are essential. Experience with specific therapeutic areas or target classes is a plus.
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Senior Pharmaceutical Research Scientist

02108 Boston, Massachusetts $130000 Annually WhatJobs

Posted 7 days ago

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full-time
Our client, a leading biopharmaceutical innovator, is seeking a highly accomplished Senior Pharmaceutical Research Scientist to spearhead groundbreaking drug discovery initiatives. This pivotal role demands a seasoned professional with a proven track record in medicinal chemistry, pharmacology, or a related life science discipline. You will be instrumental in designing, synthesizing, and characterizing novel drug candidates, progressing them through preclinical development. The ideal candidate will possess extensive expertise in modern synthetic organic chemistry techniques, in vitro and in vivo assay development, and structure-activity relationship (SAR) analysis. You will lead research projects, mentor junior scientists, and contribute significantly to the company's scientific strategy and intellectual property portfolio. A deep understanding of disease biology and target validation is essential, alongside a passion for translating scientific discoveries into life-changing therapies.

Key Responsibilities:
  • Lead the design and execution of research programs focused on identifying and optimizing novel small molecule therapeutics.
  • Utilize advanced synthetic chemistry methodologies to create diverse chemical libraries and target compounds.
  • Develop and validate innovative biochemical and cellular assays to assess compound efficacy and mechanism of action.
  • Conduct comprehensive SAR studies to guide lead optimization efforts and improve pharmacokinetic properties.
  • Interpret complex experimental data, troubleshoot research challenges, and propose strategic solutions.
  • Collaborate effectively with multidisciplinary teams, including biologists, pharmacologists, DMPK scientists, and clinical development personnel.
  • Stay abreast of the latest scientific literature, emerging technologies, and competitive intelligence in relevant therapeutic areas.
  • Prepare high-quality research reports, manuscripts for publication, and patent applications.
  • Mentor and guide junior research scientists, fostering a culture of scientific excellence and innovation.
  • Contribute to project planning, resource allocation, and budget management for research initiatives.

This dynamic position is based in Boston, Massachusetts, US . We are looking for a strategic thinker with exceptional problem-solving skills and a strong commitment to scientific rigor. A Ph.D. in Organic Chemistry, Medicinal Chemistry, Pharmacology, or a closely related field, coupled with a minimum of 5-7 years of relevant post-doctoral or industry experience, is required. Exceptional communication and presentation skills are vital for conveying complex scientific information to diverse audiences. If you are driven by innovation and aspire to make a significant impact in pharmaceutical research, we invite you to apply.
Qualifications:
  • Ph.D. in Organic Chemistry, Medicinal Chemistry, Pharmacology, or a related field.
  • 5+ years of post-doctoral or industry research experience in drug discovery.
  • Demonstrated expertise in synthetic organic chemistry and medicinal chemistry principles.
  • Experience with various in vitro and in vivo preclinical models.
  • Strong analytical skills and ability to interpret complex data sets.
  • Excellent written and verbal communication skills.
  • Proven ability to lead research projects and mentor junior staff.
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Lead Pharmaceutical Research Scientist

02110 Boston, Massachusetts $130000 Annually WhatJobs

Posted 7 days ago

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full-time
Join a groundbreaking Pharmaceutical company at the forefront of medical innovation, seeking a highly motivated and experienced Lead Pharmaceutical Research Scientist to contribute to cutting-edge drug discovery and development programs. This critical role, based at our state-of-the-art research facility in Boston, Massachusetts, US , will focus on advancing novel therapeutic candidates from early-stage research through to preclinical development. You will lead a team of talented scientists, mentor junior researchers, and oversee the design and execution of complex experiments. Your expertise will be crucial in areas such as target identification and validation, assay development, lead optimization, and pharmacodynamic/pharmacokinetic studies. The ideal candidate will possess a Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline, coupled with a minimum of 7-10 years of hands-on experience in drug discovery within the pharmaceutical or biotechnology industry. A strong publication record and a deep understanding of regulatory requirements are highly desirable. Responsibilities include developing and implementing research strategies, managing project timelines and budgets, analyzing and interpreting complex biological data, and presenting findings at internal and external scientific forums. You will collaborate closely with cross-functional teams, including medicinal chemistry, DMPK, and toxicology, to ensure a seamless transition of projects through the development pipeline. A proven ability to troubleshoot experimental challenges, innovate new approaches, and contribute to intellectual property generation is essential. This position offers a unique opportunity to make a significant impact on patient lives by driving the development of transformative medicines in a collaborative and scientifically rigorous environment. Exceptional leadership, communication, and problem-solving skills are a must.
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Senior Pharmaceutical Research Scientist

02108 Boston, Massachusetts $130000 Annually WhatJobs

Posted 7 days ago

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Job Description

full-time
Our client is a leading innovator in the pharmaceutical industry and is seeking an exceptional Senior Pharmaceutical Research Scientist to join their pioneering drug discovery team. This fully remote role offers the unique opportunity to contribute to groundbreaking research from the comfort of your home office. You will be instrumental in identifying novel therapeutic targets, designing and conducting experiments, and analyzing data to advance drug candidates through the pipeline. The ideal candidate will possess a strong scientific background, extensive experience in relevant experimental techniques, and a passion for bringing life-changing medicines to patients.

Key Responsibilities:
  • Design, execute, and optimize complex biological assays and experiments in areas such as cell biology, molecular biology, or biochemistry.
  • Identify, validate, and characterize novel drug targets for various disease indications.
  • Analyze and interpret experimental data, drawing scientifically sound conclusions.
  • Develop and implement robust experimental protocols and methodologies.
  • Troubleshoot experimental challenges and propose creative solutions.
  • Collaborate effectively with cross-functional teams, including chemists, pharmacologists, and computational biologists.
  • Contribute to the preparation of scientific manuscripts, patents, and regulatory submissions.
  • Stay current with the latest scientific literature, technological advancements, and industry trends.
  • Mentor and guide junior research staff, fostering a collaborative and innovative research environment.
  • Present research findings at internal meetings and external scientific conferences.

Qualifications:
  • Ph.D. in Molecular Biology, Cell Biology, Biochemistry, Pharmacology, or a related life science discipline.
  • Minimum of 5-7 years of post-doctoral or industry research experience in drug discovery.
  • Demonstrated expertise in a relevant therapeutic area and associated experimental techniques (e.g., protein biochemistry, cell-based assays, gene editing, flow cytometry).
  • Proven ability to design, conduct, and interpret complex biological experiments independently.
  • Strong understanding of drug discovery and development processes.
  • Excellent analytical and problem-solving skills.
  • Exceptional written and verbal communication skills, with a track record of scientific publication.
  • Experience with data analysis software and computational biology tools is a plus.
  • Ability to work effectively in a remote, collaborative team setting.
  • Self-motivated, detail-oriented, and driven by scientific curiosity.
This remote position offers a competitive salary, excellent benefits, and the chance to make a significant impact on patient health. Join our client's forward-thinking organization and be at the forefront of pharmaceutical innovation.
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Principal Pharmaceutical Research Scientist

02108 Boston, Massachusetts $170000 Annually WhatJobs

Posted 7 days ago

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full-time
Our client is seeking a highly accomplished Principal Pharmaceutical Research Scientist to lead pioneering research in drug discovery and development. This fully remote position offers an exceptional opportunity to contribute to groundbreaking therapeutic advancements within a leading pharmaceutical organization. You will be responsible for directing and executing complex research projects aimed at identifying novel drug targets, validating biological pathways, and developing innovative therapeutic compounds. Your expertise will span across areas such as medicinal chemistry, pharmacology, molecular biology, or biochemistry. You will design and interpret in vitro and in vivo studies, manage research budgets, and oversee the work of research associates and scientists. A critical aspect of this role involves staying at the forefront of scientific literature, identifying emerging technologies, and fostering collaborations with academic institutions and industry partners. The ideal candidate will possess a PhD in a relevant scientific discipline, a strong publication record, and extensive experience in drug discovery, preferably within a specific therapeutic area. Proven leadership skills, exceptional problem-solving abilities, and strong communication and presentation skills are essential for effectively conveying research findings to diverse audiences, including senior management and regulatory agencies. You should be adept at utilizing advanced research methodologies and state-of-the-art laboratory techniques. This remote role requires a strategic thinker with a deep understanding of the drug development process, from target identification to preclinical evaluation. Your contributions will be vital in bringing life-changing medicines to patients. Join our client's innovative research team and drive the future of pharmaceutical innovation. This is a unique opportunity to make a profound impact on human health through cutting-edge scientific research.
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Senior Pharmaceutical Research Scientist

02108 Boston, Massachusetts $120000 Annually WhatJobs

Posted 7 days ago

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full-time
Our client, a leading innovator in the pharmaceutical industry, is seeking a highly motivated and experienced Senior Pharmaceutical Research Scientist to join their cutting-edge research and development team in Boston, Massachusetts, US . This hybrid role offers a unique opportunity to contribute to groundbreaking discoveries that improve patient lives worldwide. You will be instrumental in designing, executing, and analyzing complex experiments to identify and validate novel drug targets and therapeutic candidates. Your expertise will guide the early-stage drug discovery process, from target identification through lead optimization.

Responsibilities include:
  • Leading and conducting in-vitro and in-vivo studies to evaluate drug efficacy and safety.
  • Developing and optimizing biochemical and cell-based assays.
  • Analyzing experimental data, interpreting results, and presenting findings to cross-functional teams.
  • Collaborating with medicinal chemists, pharmacologists, and toxicologists to advance drug candidates.
  • Designing and managing preclinical studies, including IND-enabling studies.
  • Maintaining a comprehensive understanding of relevant scientific literature and industry trends.
  • Mentoring junior scientists and contributing to a collaborative research environment.
  • Troubleshooting experimental issues and developing innovative solutions.
  • Preparing manuscripts for publication and contributing to patent filings.
  • Ensuring compliance with all safety regulations and laboratory procedures.
The ideal candidate will hold a Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related field, with a minimum of 5 years of post-doctoral or industry research experience. Proven experience in drug discovery, particularly in oncology, immunology, or a relevant therapeutic area, is required. Strong knowledge of assay development, data analysis software (e.g., GraphPad Prism, R), and experience with relevant biological techniques (e.g., PCR, Western blotting, flow cytometry) are essential. Excellent written and verbal communication skills are necessary for effective collaboration and presentation of scientific data. A track record of successful project contributions and scientific publications is highly desirable. Join our client's dedicated team and play a pivotal role in developing next-generation medicines.
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Senior Pharmaceutical Research Scientist

02108 Boston, Massachusetts $110000 Annually WhatJobs

Posted 7 days ago

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full-time
Our client, a leading biopharmaceutical innovator, is seeking a highly motivated and experienced Senior Pharmaceutical Research Scientist to join their dynamic team in Boston, Massachusetts, US . This is an exceptional opportunity to contribute to cutting-edge drug discovery and development in a collaborative and scientifically rigorous environment. The successful candidate will play a crucial role in designing, executing, and analyzing complex experiments to advance novel therapeutic candidates from early-stage research through preclinical development. Responsibilities will include the development and validation of innovative assays, characterization of drug targets, and the interpretation of biological data to inform go/no-go decisions. You will be expected to present findings to cross-functional teams, contribute to scientific publications and patent applications, and mentor junior researchers. This role requires a deep understanding of molecular biology, biochemistry, and pharmacology, with a proven track record in a relevant therapeutic area. The ideal candidate will possess excellent problem-solving skills, a meticulous approach to experimental design and execution, and the ability to work independently and as part of a team. This position offers a hybrid work model, balancing valuable in-office collaboration with the flexibility of remote work.

Key Responsibilities:
  • Design, optimize, and perform in vitro and in vivo experiments to evaluate the efficacy and safety of drug candidates.
  • Develop and validate complex biological assays for target engagement and pathway modulation.
  • Analyze and interpret experimental data, drawing sound conclusions and making recommendations.
  • Collaborate closely with medicinal chemists, pharmacologists, and toxicologists to advance projects.
  • Prepare detailed reports, presentations, and contribute to regulatory submissions.
  • Stay abreast of the latest scientific literature and technological advancements in the field.
  • Mentor and guide junior scientists in experimental techniques and data analysis.
Qualifications:
  • Ph.D. in Molecular Biology, Biochemistry, Pharmacology, or a related field.
  • Minimum of 5 years of post-doctoral or industry research experience in pharmaceutical R&D.
  • Strong expertise in at least one major therapeutic area (e.g., oncology, immunology, neuroscience).
  • Proficiency in cell culture, molecular cloning, protein analysis, and various biochemical and cell-based assay techniques.
  • Experience with animal models is a plus.
  • Excellent written and verbal communication skills.
  • Demonstrated ability to work effectively in a fast-paced, cross-functional team environment.
  • Experience with data analysis software (e.g., GraphPad Prism, R).
Apply Now

Senior Pharmaceutical Research Scientist

02108 Boston, Massachusetts $130000 Annually WhatJobs

Posted 7 days ago

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Job Description

full-time
Our client, a leading biopharmaceutical innovator, is seeking a highly motivated and experienced Senior Pharmaceutical Research Scientist to join their dynamic team in Boston, Massachusetts, US . This role is pivotal in driving the discovery and development of novel therapeutics. The ideal candidate will possess a strong background in medicinal chemistry, drug discovery, and preclinical development. Responsibilities include designing and synthesizing novel small molecules, optimizing lead compounds for efficacy and safety, and developing robust bioanalytical methods. You will collaborate closely with cross-functional teams, including biologists, pharmacologists, and toxicologists, to advance drug candidates through the pipeline. The role also involves interpreting complex experimental data, troubleshooting technical challenges, and presenting findings at internal and external forums. A key aspect of this position is staying abreast of the latest scientific advancements and competitive intelligence within the pharmaceutical industry. You will be expected to contribute to intellectual property generation and participate in the writing of research protocols and reports. The successful candidate will demonstrate excellent problem-solving skills, a meticulous approach to experimental design and execution, and the ability to work independently and as part of a collaborative research unit. Proficiency in relevant software for chemical drawing, data analysis, and literature searching is essential. The work environment is a state-of-the-art research facility, offering opportunities for professional growth and contributing to life-changing medicines. While this role offers some flexibility through a hybrid work model, requiring occasional presence in the Boston, Massachusetts, US lab, it primarily focuses on cutting-edge bench research. We are looking for individuals passionate about making a tangible impact on patient lives through innovative science. Your expertise will be instrumental in shaping the future of our drug development programs. The ability to manage multiple projects simultaneously and meet strict deadlines is crucial. Mentorship of junior scientists may also be a component of this role as the team expands.
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