Senior Pharmaceutical Research Scientist

27701 Durham, North Carolina $130000 Annually WhatJobs

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full-time
Our client is seeking a highly skilled and innovative Senior Pharmaceutical Research Scientist to join their cutting-edge research and development team in Durham, North Carolina, US . This role is central to discovering and developing novel pharmaceutical compounds and therapies. The ideal candidate will possess a strong background in medicinal chemistry, pharmacology, or a related life science discipline, coupled with extensive experience in drug discovery processes. You will be responsible for designing and executing experiments, analyzing complex biological and chemical data, and contributing to the development of preclinical and clinical candidates. Your expertise will be critical in identifying new drug targets, synthesizing and characterizing potential drug molecules, and evaluating their efficacy and safety in vitro and in vivo models. This position involves leading research projects, mentoring junior scientists, and collaborating with cross-functional teams including biology, toxicology, and clinical development. A deep understanding of molecular biology, cellular assays, and pharmacokinetics/pharmacodynamics (PK/PD) is essential. You will also be involved in scientific literature review, patent preparation, and presenting research findings at scientific conferences and to senior management. This is an exciting opportunity to contribute to the advancement of pharmaceutical science and bring life-changing medicines to patients. A proactive approach to problem-solving, meticulous experimental design, and a commitment to scientific excellence are paramount.

Responsibilities:
  • Design and conduct experiments to identify and validate new drug targets and lead compounds.
  • Synthesize, purify, and characterize novel chemical entities.
  • Evaluate the biological activity and pharmacological properties of drug candidates using in vitro and in vivo models.
  • Develop and optimize assays for drug screening and efficacy testing.
  • Analyze and interpret complex scientific data, drawing meaningful conclusions.
  • Contribute to the planning and execution of preclinical development strategies.
  • Collaborate with cross-functional teams including biology, DMPK, toxicology, and clinical research.
  • Stay abreast of the latest scientific literature and technological advancements in drug discovery.
  • Prepare scientific reports, presentations, and contribute to regulatory filings.
  • Mentor and guide junior research scientists.
Qualifications:
  • Ph.D. in Medicinal Chemistry, Pharmacology, Biochemistry, Molecular Biology, or a related field.
  • Minimum of 5 years of post-doctoral or industry experience in pharmaceutical research and drug discovery.
  • Proven track record in identifying and developing small molecule therapeutics.
  • Extensive experience with assay development, high-throughput screening, and lead optimization.
  • Strong knowledge of medicinal chemistry principles and synthetic organic chemistry.
  • Proficiency in data analysis and interpretation of biological and chemical data.
  • Experience with in vivo pharmacology and PK/PD studies.
  • Excellent written and verbal communication skills, with the ability to present complex scientific information effectively.
  • Demonstrated ability to lead research projects and collaborate within a multidisciplinary team.
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Remote Pharmaceutical Research Scientist

27513 Raleigh, North Carolina $130000 Annually WhatJobs

Posted 1 day ago

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full-time
Our client is seeking an innovative and highly motivated Remote Pharmaceutical Research Scientist to contribute to groundbreaking drug discovery and development efforts. In this fully remote position, you will play a crucial role in advancing our client's pipeline by designing and executing experiments, analyzing complex biological data, and contributing to the development of novel therapeutic agents. Your responsibilities will include planning and conducting in vitro and in vivo studies, utilizing a range of biochemical, molecular biology, and cell biology techniques. You will be expected to interpret experimental results, draw meaningful conclusions, and communicate findings effectively through written reports and presentations to cross-functional teams. A strong understanding of drug discovery principles, pharmacology, and relevant disease areas is essential. Experience with specific therapeutic modalities, such as small molecules, biologics, or gene therapies, will be highly regarded. The ideal candidate will possess excellent problem-solving skills, a meticulous approach to experimental design and execution, and a commitment to scientific rigor. You will collaborate with other research scientists, medicinal chemists, and clinical development teams, contributing to a dynamic and fast-paced research environment. Proficiency with data analysis software and scientific literature databases is required. This role offers the unique opportunity to work on cutting-edge pharmaceutical research from the convenience of your home office, contributing significantly to the development of life-saving medicines. Join our client's dedicated team and make a tangible impact on global health.

Responsibilities:
  • Design and conduct experiments to support drug discovery and development programs.
  • Utilize a variety of molecular biology, cell biology, and biochemistry techniques.
  • Analyze and interpret complex experimental data.
  • Prepare detailed scientific reports and present findings to research teams.
  • Collaborate with cross-functional teams, including medicinal chemistry and clinical development.
  • Stay current with scientific literature and advancements in relevant therapeutic areas.
  • Contribute to the development of novel therapeutic strategies.
  • Troubleshoot experimental procedures and optimize protocols.
  • Maintain accurate laboratory records and documentation.
  • Adhere to all safety and ethical guidelines.
Qualifications:
  • Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science field.
  • Minimum of 3 years of post-doctoral or industry research experience in pharmaceutical R&D.
  • Proven expertise in relevant experimental techniques and methodologies.
  • Strong understanding of drug discovery processes and principles.
  • Excellent analytical and problem-solving skills.
  • Proficiency in data analysis software and scientific databases.
  • Strong written and verbal communication skills.
  • Ability to work independently and collaboratively in a remote setting.
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Senior Pharmaceutical Research Scientist

27514 Raleigh, North Carolina $130000 Annually WhatJobs

Posted 1 day ago

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Job Description

full-time
Our client, a leading pharmaceutical company, is seeking a highly skilled and experienced Senior Pharmaceutical Research Scientist to join their innovative drug discovery and development team. This role operates on a fully remote basis, offering a unique opportunity for experienced scientists to contribute to cutting-edge research from their home offices. The successful candidate will be responsible for designing, executing, and analyzing experiments aimed at identifying and validating novel therapeutic targets and developing small molecule drugs. You will leverage your expertise in medicinal chemistry, pharmacology, and assay development to drive research projects from early discovery through preclinical development. This position demands a strong scientific acumen, meticulous experimental planning, and the ability to interpret complex data sets.

Key responsibilities include:
  • Designing and conducting in vitro and in vivo experiments to assess drug efficacy and safety.
  • Developing and optimizing biological assays for target validation and screening.
  • Synthesizing and characterizing potential drug candidates using organic chemistry techniques.
  • Analyzing experimental data, interpreting results, and drawing meaningful conclusions.
  • Collaborating with cross-functional teams, including medicinal chemists, biologists, and toxicologists.
  • Staying abreast of the latest scientific literature and technological advancements in relevant therapeutic areas.
  • Preparing scientific reports, presentations, and publications.
  • Contributing to the intellectual property portfolio through patent filings.
  • Mentoring junior research staff and contributing to a collaborative research environment.
  • Managing external collaborations with academic institutions and contract research organizations.

We require a Ph.D. in Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry, or a closely related field, with a minimum of 5-7 years of relevant postdoctoral and/or industry experience in drug discovery. A strong publication record and demonstrated success in leading research projects are essential. Expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is highly desirable. Proficiency in a range of biological techniques, including cell culture, molecular biology, and biochemical assays, is required. Experience with data analysis software and statistical methods is necessary. Excellent communication, presentation, and interpersonal skills are crucial for effective collaboration in a remote setting. This role is based out of our Raleigh, North Carolina, US research hub, but offers full remote work flexibility. Join us in advancing the future of medicine.
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Senior Pharmaceutical Research Scientist

27701 Durham, North Carolina $140000 Annually WhatJobs

Posted 2 days ago

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Job Description

full-time
Our client, a dynamic biopharmaceutical company, is seeking a highly motivated Senior Pharmaceutical Research Scientist to join their cutting-edge R&D team in Durham, North Carolina, US . This hands-on role is central to the discovery and development of novel therapeutic agents. The successful candidate will lead research projects, contribute to the design and execution of experiments, and play a key role in advancing drug candidates through the preclinical pipeline. You will be expected to operate with a high degree of independence, interpret complex data, and contribute to scientific publications and patent filings.

Key responsibilities include:
  • Designing and executing in vitro and in vivo experiments to evaluate drug candidates.
  • Developing and validating assays for target identification and validation.
  • Analyzing and interpreting experimental data, drawing conclusions, and proposing next steps.
  • Leading specific research projects, including planning, execution, and reporting.
  • Collaborating effectively with cross-functional teams, including medicinal chemistry, pharmacology, and DMPK.
  • Preparing scientific reports, presentations, and contributing to manuscripts for publication.
  • Contributing to the generation of intellectual property (patent applications).
  • Mentoring and guiding junior research staff.
  • Staying abreast of the latest scientific literature and technological advancements in the field.
  • Ensuring compliance with all laboratory safety regulations and company policies.
The ideal candidate will possess a Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline. A strong track record of research accomplishments, evidenced by publications and presentations, is required. A minimum of 5 years of post-doctoral or industry research experience in drug discovery is essential. Extensive experience with relevant biological assays, cellular models, and small molecule drug discovery is mandatory. Proficiency in data analysis software and strong understanding of pharmacokinetic and pharmacodynamic principles are critical. Excellent written and oral communication skills, along with the ability to work effectively in a collaborative research environment, are paramount. Experience with biologics or antibody research is a plus. This is an exciting opportunity to contribute to the development of life-changing medicines.
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Senior Pharmaceutical Research Scientist

27513 Raleigh, North Carolina $110000 Annually WhatJobs

Posted 3 days ago

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Job Description

full-time
Our client, a leading innovator in the pharmaceutical sector, is seeking a highly skilled and motivated Senior Pharmaceutical Research Scientist to join their dynamic team in Raleigh, North Carolina, US . This is an exciting opportunity to contribute to cutting-edge drug discovery and development processes. The successful candidate will be responsible for designing, executing, and analyzing complex experiments aimed at identifying and validating novel therapeutic targets. You will play a critical role in the preclinical stages of drug development, including compound screening, lead optimization, and mechanism of action studies. This position requires a deep understanding of organic chemistry, medicinal chemistry, and pharmacology, with a strong emphasis on in vitro and in vivo study design and interpretation. Key responsibilities include managing multiple research projects simultaneously, collaborating with cross-functional teams including toxicology, DMPK, and clinical development, and presenting research findings at internal meetings and external scientific conferences. The ideal candidate will possess excellent problem-solving abilities, a meticulous approach to data recording and analysis, and a proven track record of scientific achievement as evidenced by publications and patents. You will also be involved in mentoring junior scientists and contributing to the strategic direction of research programs. This role requires extensive experience in a laboratory setting, proficiency with standard molecular biology and biochemistry techniques, and familiarity with high-throughput screening platforms. A Ph.D. in Chemistry, Pharmacology, Biochemistry, or a related field is essential, along with a minimum of 5 years of post-doctoral or industry research experience. Strong communication and interpersonal skills are vital for success in this collaborative environment. Experience with biologics and antibody drug conjugate development is a plus. Join us and make a significant impact on the future of medicine.
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Senior Pharmaceutical Research Scientist

27514 Raleigh, North Carolina $130000 Annually WhatJobs

Posted 4 days ago

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Job Description

full-time
Our client is a leading biopharmaceutical company seeking a highly skilled Senior Pharmaceutical Research Scientist to join their innovative drug discovery team in Raleigh, North Carolina, US . This role is crucial for advancing our pipeline of novel therapeutics through rigorous scientific research and development. The ideal candidate will possess extensive experience in pharmaceutical R&D, a strong background in medicinal chemistry or a related discipline, and a proven ability to lead complex research projects from concept to preclinical development. This hybrid position requires significant time in the lab, complemented by remote work for data analysis, report writing, and strategic planning. We are looking for a creative problem-solver with a passion for scientific innovation and a commitment to bringing life-changing medicines to patients.

Responsibilities:
  • Design and execute innovative research projects to identify and optimize novel drug candidates.
  • Conduct complex experiments in medicinal chemistry, pharmacology, or a related field.
  • Analyze and interpret experimental data, drawing sound scientific conclusions.
  • Develop and validate new assays and methodologies to support drug discovery efforts.
  • Collaborate effectively with cross-functional teams, including biologists, toxicologists, and formulation scientists.
  • Prepare detailed research reports, scientific publications, and patent applications.
  • Mentor junior scientists and provide technical guidance.
  • Stay current with the latest scientific literature and technological advancements in the pharmaceutical industry.
  • Contribute to the strategic planning and prioritization of research programs.
  • Ensure compliance with all safety regulations and laboratory best practices.

Qualifications:
  • Ph.D. in Medicinal Chemistry, Organic Chemistry, Pharmacology, or a closely related field.
  • Minimum of 5-7 years of post-doctoral research experience in the pharmaceutical or biotech industry.
  • Proven track record of successfully contributing to drug discovery programs.
  • Expertise in synthetic organic chemistry and structure-activity relationship (SAR) analysis.
  • Strong understanding of drug metabolism and pharmacokinetic (DMPK) principles.
  • Proficiency in relevant analytical techniques (e.g., HPLC, NMR, Mass Spectrometry).
  • Excellent problem-solving, critical-thinking, and experimental design skills.
  • Strong written and verbal communication skills, with experience presenting scientific findings.
  • Ability to work independently and collaboratively in a fast-paced research environment.
  • Experience with computational chemistry tools is a plus.

This hybrid role is based in our Raleigh, North Carolina, US facility. Some remote work flexibility is available for data analysis and reporting activities.
Apply Now

Senior Pharmaceutical Research Scientist

27703 Chapel Hill, North Carolina $120000 Annually WhatJobs

Posted 4 days ago

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Job Description

full-time
Our client, a leader in innovative pharmaceutical development, is seeking a highly skilled and motivated Senior Pharmaceutical Research Scientist to join their cutting-edge, fully remote team. This pivotal role will focus on the discovery and optimization of novel therapeutic agents. You will be instrumental in designing and executing complex experimental protocols, analyzing data, and contributing to the intellectual property strategy of the company. The ideal candidate will possess a deep understanding of medicinal chemistry, pharmacology, and drug metabolism, coupled with a proven track record in preclinical research.

Responsibilities:
  • Lead independent research projects from conception to completion, focusing on target identification, lead optimization, and candidate selection.
  • Design and synthesize novel small molecules with desired pharmacological properties.
  • Develop and validate in vitro and in vivo assays to evaluate drug efficacy and safety.
  • Perform pharmacokinetic and pharmacodynamic studies, and interpret complex datasets.
  • Collaborate closely with cross-functional teams, including biology, DMPK, and toxicology departments, to advance drug candidates through the development pipeline.
  • Prepare high-quality scientific reports, manuscripts for publication, and presentations for internal and external stakeholders.
  • Contribute to patent applications and maintain a strong understanding of the competitive landscape.
  • Mentor junior scientists and contribute to a collaborative and innovative research environment.
  • Stay abreast of the latest scientific literature and emerging technologies in pharmaceutical R&D.
  • Manage external collaborations and contract research organizations as needed.
Qualifications:
  • Ph.D. in Organic Chemistry, Medicinal Chemistry, Pharmacology, or a related field.
  • Minimum of 5-7 years of post-doctoral or industry experience in pharmaceutical drug discovery.
  • Demonstrated expertise in synthetic organic chemistry, including modern synthetic methodologies and purification techniques.
  • Strong understanding of ADME/PK principles and their application in drug design.
  • Experience with various pharmacological assays and cell-based models.
  • Excellent analytical and problem-solving skills, with the ability to interpret complex biological and chemical data.
  • Proven ability to work independently and manage multiple projects simultaneously in a remote setting.
  • Exceptional written and verbal communication skills, with a track record of impactful scientific presentations.
  • Proficiency in scientific databases and chemical drawing software.
  • A proactive and results-oriented mindset, with a passion for scientific innovation.
This is a fully remote position based in Durham, North Carolina, US , offering a competitive salary, comprehensive benefits package, and the opportunity to make a significant impact on the future of medicine. If you are a dedicated scientist looking for a challenging and rewarding remote opportunity, we encourage you to apply.
Apply Now
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Remote Pharmaceutical Research Scientist

27513 Chapel Hill, North Carolina $120000 Annually WhatJobs

Posted 4 days ago

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Job Description

full-time
Our client, a leading innovator in the pharmaceutical industry, is seeking a highly skilled and motivated Remote Pharmaceutical Research Scientist. This role is integral to our drug discovery and development pipeline, focusing on cutting-edge research that will shape the future of healthcare. As a remote employee, you will leverage advanced scientific knowledge and techniques to contribute to groundbreaking projects from your home office.

Responsibilities:
  • Conduct in-silico and ex-vivo research, analyzing complex biological and chemical data to identify potential drug targets and therapeutic strategies.
  • Design and oversee experimental protocols for drug efficacy and safety testing, often in collaboration with external research institutions.
  • Interpret experimental results, draw meaningful conclusions, and present findings to cross-functional teams, including chemists, biologists, and clinicians.
  • Author and review scientific publications, patents, and regulatory submission documents.
  • Contribute to the strategic planning and direction of research programs.
  • Mentor junior scientists and research associates.
  • Stay abreast of the latest scientific advancements, methodologies, and competitive landscape in relevant therapeutic areas.
  • Ensure compliance with all relevant ethical, safety, and regulatory guidelines.
Qualifications:
  • Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life sciences discipline.
  • Minimum of 5 years of post-doctoral or industry research experience in pharmaceutical drug discovery.
  • Demonstrated expertise in one or more therapeutic areas (e.g., oncology, immunology, neurology).
  • Strong understanding of drug development processes, from target identification to preclinical studies.
  • Proficiency in bioinformatics tools, statistical analysis software, and data visualization techniques.
  • Excellent written and verbal communication skills, with a proven ability to articulate complex scientific concepts clearly.
  • Experience working effectively in a remote or distributed research team environment.
  • Demonstrated ability to independently manage research projects and troubleshoot complex scientific challenges.
  • Strong analytical and problem-solving skills.
This fully remote position offers a unique opportunity to work on impactful pharmaceutical research, collaborating with world-class scientists while enjoying the flexibility of a home-based role. If you are driven by scientific curiosity and possess a deep understanding of pharmaceutical research, we invite you to apply. This role serves the **Durham, North Carolina, US** region.
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Senior Pharmaceutical Research Scientist

27705 Chapel Hill, North Carolina $120000 Annually WhatJobs

Posted 4 days ago

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Job Description

full-time
Our client is seeking a highly motivated and experienced Senior Pharmaceutical Research Scientist to join their innovative drug discovery team. This is a fully remote, full-time position, offering the flexibility to work from anywhere within the United States. You will play a critical role in the entire lifecycle of drug development, from initial hypothesis generation and target identification to preclinical validation and IND submission support. Your expertise in molecular biology, pharmacology, and medicinal chemistry will be essential in designing and executing complex experiments, analyzing data, and contributing to the strategic direction of our research programs. This role demands a strong understanding of assay development, high-throughput screening, and in vivo pharmacology. You will be responsible for mentoring junior scientists, fostering a collaborative research environment, and staying abreast of the latest scientific advancements in relevant therapeutic areas. The ideal candidate will possess excellent problem-solving skills, a proven track record of publications and presentations, and the ability to effectively communicate complex scientific information to diverse audiences, including cross-functional teams and senior management. While this role is remote, occasional virtual team meetings and lab visits may be required. We are committed to fostering a culture of scientific excellence and providing opportunities for professional growth and development within a dynamic and supportive remote-first setting. You will work with cutting-edge technologies and contribute to the development of novel therapeutics that address unmet medical needs. This position is ideal for a self-starter who thrives in an independent work environment while maintaining strong connections with a distributed team.

Responsibilities:
  • Design, optimize, and execute in vitro and in vivo experiments to evaluate drug candidates.
  • Develop and validate novel biological assays for target engagement and efficacy studies.
  • Analyze and interpret complex experimental data, troubleshoot experiments, and propose next steps.
  • Contribute to the planning and execution of preclinical development strategies.
  • Prepare scientific reports, presentations, and manuscripts for internal and external dissemination.
  • Mentor and guide junior research staff.
  • Collaborate effectively with medicinal chemists, pharmacologists, and toxicologists.
  • Stay current with the scientific literature and emerging technologies in relevant therapeutic areas.
Qualifications:
  • Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related field.
  • Minimum of 5 years of relevant postdoctoral or industry experience in drug discovery.
  • Demonstrated expertise in molecular biology techniques, cell-based assays, and PK/PD studies.
  • Experience with biologics or small molecule drug development.
  • Excellent written and verbal communication skills.
  • Ability to work independently and as part of a remote team.
  • Proficiency in data analysis software (e.g., GraphPad Prism, R).
Apply Now

Senior Pharmaceutical Research Scientist

27701 Durham, North Carolina $135000 Annually WhatJobs

Posted 5 days ago

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Job Description

full-time
Our client, a cutting-edge pharmaceutical company, is seeking a highly skilled and innovative Senior Pharmaceutical Research Scientist to join their esteemed research and development team in Durham, North Carolina, US . This role is critical for advancing novel drug discovery and development programs. You will lead research projects, design and conduct experiments, and analyze complex data to contribute to the development of new therapeutic agents. The ideal candidate possesses a strong background in medicinal chemistry, pharmacology, or a related field, with a proven track record of scientific achievement and a passion for innovation. This is an exceptional opportunity to make a significant contribution to healthcare and advance your career in pharmaceutical research.

Responsibilities:
  • Lead and manage research projects focused on identifying and developing new drug candidates.
  • Design, optimize, and execute in vitro and in vivo experiments to assess drug efficacy and safety.
  • Analyze and interpret complex biological and chemical data, drawing sound scientific conclusions.
  • Contribute to the development of research strategies and proposals.
  • Collaborate with cross-functional teams, including chemists, biologists, toxicologists, and clinical researchers.
  • Stay abreast of the latest scientific literature and technological advancements in the pharmaceutical industry.
  • Prepare and present research findings at scientific conferences and in publications.
  • Mentor junior scientists and contribute to a collaborative research environment.
  • Ensure compliance with all laboratory safety regulations and protocols.
  • Contribute to the intellectual property portfolio through invention disclosures and patent applications.

Qualifications:
  • Ph.D. in Pharmacology, Medicinal Chemistry, Biology, or a related life science discipline.
  • Minimum of 5 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
  • Proven expertise in drug discovery and development processes.
  • Strong experience with relevant experimental techniques and assays.
  • Excellent analytical, problem-solving, and critical thinking skills.
  • Demonstrated ability to manage research projects independently and effectively.
  • Strong publication record and/or patent filings.
  • Excellent written and verbal communication skills, with the ability to present scientific data clearly.
  • Experience working in a team-oriented, collaborative environment.
  • Knowledge of regulatory requirements for drug development is a plus.
Apply Now
 

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