1 Amgen jobs in Thousand Oaks

Senior Scientist/Principal Scientist - CNS Drug Delivery
**Job Summary:**
Our client is a cutting-edge neuroscience company developing innovative brain shuttle technology aimed at revolutionizing the delivery of drugs and molecules to the brain. This proprietary platform is designed to overcome the blood-brain barrier and provide groundbreaking solutions for treating Alzheimer's disease, neurodegenerative disorders, and psychiatric conditions. As a well-funded biotech firm, they offer a unique opportunity to join a highly dynamic team dedicated to advancing CNS drug delivery technologies. We are seeking a Senior Scientist/Principal Scientist to lead bioanalytical and biodistribution studies, manage IND-enabling efforts, and contribute to the development of this novel brain shuttle platform.
**Job Specifications:**
+ **Job Type:** Full-time
+ **Company:** Leading Neuroscience Biotech Company
+ **Location:** Thousand Oaks
+ **Pay Rate:** $160,000 annually (flexible for highly experienced candidates)
+ **Shift:** Day Shift
**Roles and Responsibilities:**
+ Lead and execute bioanalytical and biodistribution studies to advance CNS drug delivery platforms.
+ Develop and validate assays for quantifying drug levels in plasma, brain, and other tissues.
+ Design and interpret Pharmacokinetic/Pharmacodynamic (PK/PD) studies to evaluate drug delivery, efficacy, and safety.
+ Manage IND-enabling studies, collaborating closely with internal teams and external CRO partners to ensure timely execution and compliance.
+ Mentor and guide junior scientists, fostering a collaborative and innovative research environment.
+ Stay abreast of the latest scientific advances in CNS drug delivery, bioanalysis, and regulatory frameworks to ensure research practices are aligned with industry standards.
**Qualifications & Skills:**
+ **Education:** PhD in a life sciences field (e.g., Neuroscience, Pharmacology, Biology) or related discipline.
+ **Experience:** 8-10+ years of industry experience in bioanalytics, biodistribution, and PK/PD studies, ideally with large molecules (antibodies, oligonucleotides, peptides). CNS-related experience is highly preferred.
+ Proven track record of managing IND-enabling studies and working effectively with CROs.
+ Expertise in blood-brain barrier biology and CNS drug delivery technologies.
+ Strong background in bioanalytical methods, including ELISA, RT-qPCR, and histology.
+ Excellent problem-solving skills, scientific rigor, and the ability to thrive in a fast-paced, dynamic research environment.
+ Experience in managing and mentoring scientific teams, with a focus on study design and execution rather than performance reviews.
**Opportunities:**
+ Lead pioneering research in CNS drug delivery, contributing to the development of transformative therapeutics for neurodegenerative and psychiatric disorders.
+ Collaborate with a talented and driven team of scientists to push the boundaries of biotechnology and neuroscience.
+ Potential for career advancement within a rapidly growing, well-funded biotech company at the forefront of drug delivery innovation.
**Company Culture:**
Join a dynamic, passionate team at a cutting-edge neuroscience company where creativity, collaboration, and scientific excellence drive our mission. Our supportive work environment empowers team members to explore new ideas, grow professionally, and contribute to making a lasting impact on healthcare solutions for neurodegenerative diseases.
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