13 Drug Formulation jobs in the United States
Principal Pharmaceutical Scientist - Drug Formulation
63101 St. Louis, Missouri
$150000 Annually
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Posted 2 days ago
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Our client, a globally recognized pharmaceutical company, is seeking an accomplished Principal Pharmaceutical Scientist to lead advanced drug formulation development in **St. Louis, Missouri, US**. This senior position is crucial for driving innovation in the creation of novel drug delivery systems and optimizing the formulation of existing and pipeline compounds. You will be responsible for guiding research projects, mentoring junior scientists, and contributing to regulatory submissions. The ideal candidate possesses a Ph.D. in Pharmaceutical Sciences, Chemistry, or a related field, with extensive experience in solid dosage form development, pre-formulation studies, and excipient selection. This is a unique opportunity to make a significant impact on the development of life-saving therapies.
Responsibilities:
Qualifications:
Responsibilities:
- Lead the formulation development of complex drug candidates from pre-clinical through to commercialization stages.
- Design and execute pre-formulation studies, including solubility, stability, and compatibility assessments.
- Develop robust and scalable manufacturing processes for solid oral dosage forms (tablets, capsules).
- Evaluate and select appropriate excipients to achieve desired drug release profiles and bioavailability.
- Conduct hands-on laboratory work, including formulation preparation, analytical testing, and process optimization.
- Troubleshoot formulation challenges and identify root causes for development issues.
- Prepare detailed formulation development reports, protocols, and summaries for regulatory filings (e.g., IND, NDA).
- Collaborate with analytical development, process engineering, and manufacturing teams to ensure successful scale-up and technology transfer.
- Stay current with industry trends, new technologies, and regulatory guidelines related to drug formulation and delivery.
- Mentor and guide junior scientists, fostering their technical and professional growth.
- Contribute to intellectual property strategy by identifying patentable inventions.
- Manage multiple projects simultaneously, prioritizing tasks and ensuring timely project completion.
- Conduct literature reviews and competitive landscaping for formulation strategies.
- Provide technical expertise and support for formulation-related queries from manufacturing and quality assurance.
- Present scientific findings at internal meetings and external conferences.
Qualifications:
- Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, Chemical Engineering, or a related discipline.
- Minimum of 8-10 years of experience in pharmaceutical drug formulation development, with a strong focus on solid oral dosage forms.
- In-depth knowledge of pre-formulation techniques, excipient science, and drug delivery principles.
- Hands-on experience with various formulation development equipment and analytical techniques (e.g., HPLC, dissolution testing, DSC, TGA).
- Proven experience in developing formulations for challenging molecules (e.g., low solubility, low permeability).
- Strong understanding of cGMP requirements and regulatory guidelines (FDA, EMA).
- Excellent scientific judgment, problem-solving skills, and attention to detail.
- Demonstrated leadership capabilities and the ability to mentor junior staff.
- Strong written and verbal communication skills, with the ability to effectively present complex scientific information.
- Experience with bioavailability enhancement technologies and controlled release systems is highly desirable.
- Ability to manage multiple projects and priorities effectively in a fast-paced environment.
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0
Senior Pharmaceutical Scientist - Drug Formulation
55401 Minneapolis, Minnesota
$130000 Annually
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Posted 3 days ago
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Our client, a leading pharmaceutical company, is looking for an experienced Senior Pharmaceutical Scientist specializing in Drug Formulation to join their fully remote research and development team. This role is integral to advancing our pipeline of innovative medicines from early-stage development through to commercialization. You will be responsible for the design, development, and optimization of drug delivery systems and formulations for various therapeutic areas. This includes conducting pre-formulation studies, identifying suitable excipients, and developing robust manufacturing processes for oral, injectable, and topical dosage forms. Your expertise will be crucial in troubleshooting formulation challenges and ensuring the stability, bioavailability, and efficacy of our drug candidates. Key responsibilities include planning and executing formulation development studies, analyzing experimental data, and documenting all activities in detailed reports and regulatory submissions. You will collaborate closely with internal teams, including analytical development, regulatory affairs, and clinical operations, as well as external partners and contract manufacturing organizations. The ideal candidate will hold a Master's or Ph.D. in Pharmaceutical Sciences, Chemistry, or a related discipline, with a minimum of 7 years of progressive experience in pharmaceutical formulation development. A deep understanding of drug delivery technologies, excipient science, and regulatory guidelines (e.g., FDA, EMA) is essential. Strong analytical skills, proficiency in laboratory techniques, and experience with Good Manufacturing Practices (GMP) are required. This is a remote-first position, requiring excellent communication and self-management skills to thrive in a virtual environment. We seek a highly motivated, results-oriented scientist passionate about bringing life-changing therapies to patients.
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1
Senior Formulation Scientist - Drug Development
50309 Des Moines, Iowa
$130000 Annually
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Posted today
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Our client, a leading pharmaceutical company, is seeking a highly skilled Senior Formulation Scientist to join their innovative Research and Development team in **Des Moines, Iowa, US**. This role is critical for the development of novel drug formulations and will involve hands-on laboratory work, leading formulation projects, and contributing to the advancement of drug candidates from pre-clinical stages through to clinical trials. You will leverage your expertise in pharmaceutical sciences, including drug delivery systems, excipient selection, and analytical characterization, to create safe and effective drug products. The ideal candidate possesses a deep understanding of formulation development principles and a strong commitment to scientific excellence.
Responsibilities:
Responsibilities:
- Design and execute experiments for the formulation development of various dosage forms (e.g., oral solids, injectables, topical).
- Evaluate and select appropriate excipients and drug delivery technologies.
- Perform pre-formulation studies, including solubility, stability, and compatibility assessments.
- Develop and optimize manufacturing processes for drug products.
- Conduct analytical testing to characterize formulated products (e.g., HPLC, dissolution, particle size analysis).
- Prepare formulation development reports, protocols, and regulatory submission documents.
- Collaborate with cross-functional teams, including analytical development, process development, and clinical operations.
- Troubleshoot formulation challenges and identify solutions to optimize product performance.
- Stay current with scientific literature, industry trends, and regulatory guidelines in pharmaceutical formulation.
- Mentor junior scientists and contribute to the scientific growth of the R&D department.
- Ph.D. or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, or a related discipline.
- Minimum of 5 years of experience in pharmaceutical formulation development.
- Proven expertise in developing various dosage forms and understanding drug delivery principles.
- Hands-on experience with formulation characterization techniques and analytical instrumentation.
- Knowledge of regulatory requirements (e.g., FDA, EMA) for drug product development.
- Strong understanding of GMP principles.
- Excellent experimental design, problem-solving, and data analysis skills.
- Effective communication and interpersonal skills, with the ability to collaborate effectively.
- Experience with solid-state characterization and stability studies.
- A proactive approach and a commitment to innovation in drug development.
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2
Senior Formulation Scientist, Drug Discovery
83701 Emmett, Idaho
$105000 Annually
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Posted 1 day ago
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Our client, a rapidly growing pharmaceutical company, is seeking a highly motivated and experienced Senior Formulation Scientist to join their cutting-edge drug discovery and development team. This fully remote position allows you to contribute significantly to our mission of bringing life-changing therapies to patients. The ideal candidate will possess a strong background in pharmaceutical formulation development, with expertise in various dosage forms and drug delivery systems. You will be instrumental in designing, developing, and optimizing drug formulations to support preclinical and clinical studies. Key responsibilities include:
- Designing and executing studies for the development of various dosage forms (e.g., oral solid dosage, injectables, topical formulations).
- Investigating and selecting appropriate excipients and drug delivery technologies to optimize drug performance and bioavailability.
- Developing robust and scalable formulation processes.
- Characterizing formulated drug products using various analytical techniques (e.g., HPLC, dissolution testing, particle size analysis).
- Conducting stability studies and analyzing results to determine shelf-life and storage conditions.
- Troubleshooting formulation challenges and identifying potential solutions.
- Collaborating with analytical development, biology, and chemistry teams to achieve project goals.
- Preparing comprehensive formulation development reports and contributing to regulatory filings.
- Staying abreast of the latest advancements in pharmaceutical formulation and drug delivery.
- Mentoring junior scientists and contributing to the scientific advancement of the department.
- Ensuring all research activities are conducted in compliance with GxP guidelines.
- Ph.D. or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, or a related discipline.
- Minimum of 5 years of experience in pharmaceutical formulation development.
- Proven experience with the development of multiple dosage forms, including solid dosage and/or parenteral formulations.
- Strong understanding of physical chemistry, material science, and drug delivery principles.
- Proficiency with analytical techniques relevant to formulation characterization and quality control.
- Excellent problem-solving, analytical, and critical thinking skills.
- Strong written and verbal communication abilities, with experience in report writing.
- Ability to work independently and manage multiple projects simultaneously in a remote setting.
- Experience with regulatory requirements for drug development is a plus.
- A collaborative spirit and a commitment to scientific rigor.
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3
Senior Formulation Scientist, Drug Development
27513 Raleigh, North Carolina
$130000 Annually
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Posted 3 days ago
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Job Description
Our client, a pioneering pharmaceutical company dedicated to advancing healthcare solutions, is seeking a talented Senior Formulation Scientist to contribute to their innovative drug development pipeline in Raleigh, North Carolina . This role is central to the design, development, and optimization of novel drug delivery systems and dosage forms for a range of therapeutic areas. You will be responsible for leading formulation development activities, from pre-clinical stages through to clinical trials and potential commercialization. Key responsibilities include designing experimental studies, evaluating excipients, performing stability testing, and developing robust analytical methods to characterize formulations. The ideal candidate will have a Master's degree or Ph.D. in Pharmaceutics, Chemistry, Chemical Engineering, or a related scientific discipline, with at least 5 years of experience in pharmaceutical formulation development. Experience with various dosage forms (e.g., oral solid dosage, parenteral, topical) and a strong understanding of drug-excipient interactions, pharmacokinetics, and regulatory requirements are essential. Excellent analytical, problem-solving, and project management skills, along with strong written and verbal communication abilities, are required. This is an exciting opportunity to work on cutting-edge pharmaceutical projects within a collaborative and science-driven environment, offering a competitive salary, exceptional benefits, and significant opportunities for professional growth.
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4
Senior Formulation Scientist, Drug Development
76102 Fort Worth, Texas
$125000 Annually
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Posted 4 days ago
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Job Description
Our client, a leading pharmaceutical company, is seeking a highly experienced Senior Formulation Scientist to drive drug product development in **Fort Worth, Texas, US**. This role is critical for designing innovative and effective drug delivery systems. The ideal candidate will possess deep expertise in pharmaceutical formulation, dosage form development, and a thorough understanding of regulatory requirements for drug approval.
Responsibilities:
Responsibilities:
- Design, develop, and optimize novel drug formulations for various dosage forms (e.g., oral solids, injectables, topicals).
- Conduct pre-formulation studies to characterize active pharmaceutical ingredients (APIs) and excipients.
- Develop and validate analytical methods for drug product testing and stability studies.
- Scale up formulations from laboratory bench to pilot and commercial manufacturing.
- Prepare comprehensive formulation development reports, protocols, and CMC (Chemistry, Manufacturing, and Controls) documentation.
- Collaborate closely with process development, analytical development, regulatory affairs, and project management teams.
- Troubleshoot formulation and manufacturing challenges.
- Stay current with scientific literature, industry trends, and new technologies in pharmaceutical formulation.
- Conduct literature reviews and feasibility studies for new drug candidates.
- Ensure all activities comply with Good Manufacturing Practices (GMP) and other relevant regulatory guidelines.
- Present scientific findings and project updates to internal teams and external stakeholders.
- Mentor junior scientists and provide technical guidance.
- Contribute to intellectual property generation through patent applications.
- Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field.
- Minimum of 5-7 years of experience in pharmaceutical formulation development, with a proven track record of bringing drug products through development stages.
- Extensive knowledge of various dosage forms and drug delivery technologies.
- Experience with GMP manufacturing environments and regulatory submission processes (IND, NDA).
- Proficiency in common laboratory equipment and analytical techniques (e.g., HPLC, dissolution testing).
- Strong understanding of material science, physical chemistry, and biopharmaceutics.
- Excellent problem-solving, analytical, and critical thinking skills.
- Exceptional written and oral communication skills.
- Ability to manage multiple projects simultaneously and meet tight deadlines.
- Experience with sterile product formulation and aseptic processing is a plus.
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5
Senior Formulation Scientist - Drug Development
37201 Nashville, Tennessee
$125000 Annually
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Posted 4 days ago
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Job Description
Our client, a pioneering pharmaceutical company committed to advancing healthcare through innovative drug development, is looking for a highly motivated and experienced Senior Formulation Scientist to join their dynamic team in Nashville, Tennessee, US . This critical role will focus on the design, development, and optimization of novel drug delivery systems and dosage forms for a range of therapeutic areas. You will be responsible for leading formulation development activities, including pre-formulation studies, excipient compatibility, stability testing, and manufacturing process development. This involves hands-on laboratory work, troubleshooting formulation challenges, and ensuring that formulations meet regulatory requirements and product performance specifications. Collaboration with cross-functional teams, including analytical development, pharmacology, regulatory affairs, and manufacturing, is essential to successfully transition products from development to commercialization. A deep understanding of pharmaceutical sciences, including principles of solubility enhancement, bioavailability, controlled release, and sterile manufacturing, is required. You will also be responsible for literature reviews, developing intellectual property, and preparing regulatory submission documents. A Ph.D. or Master's degree in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or a related field is required, along with a minimum of 5 years of relevant industry experience in pharmaceutical formulation development. Experience with various dosage forms (e.g., oral solids, injectables, topical) and solid-state characterization techniques is highly desirable. If you are passionate about shaping the future of medicine and contributing to life-saving therapies in Nashville, Tennessee, US , we encourage you to explore this opportunity.
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Senior Formulation Scientist (Drug Delivery)
23451 Virginia Beach, Virginia
$125000 Annually
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Posted 7 days ago
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Job Description
Our client, a globally recognized pharmaceutical company at the forefront of developing innovative drug delivery systems, is seeking a highly skilled Senior Formulation Scientist for its research and development hub in Virginia Beach, Virginia, US . This role is central to advancing our pipeline by designing and optimizing novel drug formulations for various therapeutic areas. You will be responsible for pre-formulation studies, excipient selection, formulation development, and scale-up activities, utilizing state-of-the-art analytical and characterization techniques. The ideal candidate will possess a Ph.D. or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a closely related field, with a minimum of 6-8 years of direct experience in pharmaceutical formulation development. Expertise in parenteral formulations, controlled-release technologies, or novel delivery systems (e.g., nanoparticles, liposomes) is highly desirable. Responsibilities include conducting formulation optimization experiments, evaluating drug stability, developing analytical methods for characterization, and preparing comprehensive documentation for regulatory submissions. You will collaborate closely with colleagues in analytical development, process chemistry, and regulatory affairs. Excellent problem-solving abilities, a strong understanding of physical chemistry and material science principles, and proficiency in relevant scientific literature and regulatory guidelines are required. This is an exceptional opportunity to contribute significantly to the advancement of medicines and patient care from our facility in Virginia Beach, Virginia, US .
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7
Associate Director, Formulation Development, Drug Product
19462 Whitemarsh Township, Pennsylvania
Harmony Biosciences Holdings, Inc.
Posted 24 days ago
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Job Description
Harmony Biosciences is recruiting for an Associate Director, Formulation Development, Drug Product In this role you will support the Manufacturing Development Operations organization for Harmony Biosciences. Responsibilities include direct oversight of multiple drug product development programs of diverse dosage forms for adult and pediatric indications. The position will serve as a scientific technical expert for CMC activities for early and late-stage programs leading to the manufacture of clinical trial material to support life cycle management and new programs.
Responsibilities include but are not limited to:
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Harmony Biosciences is a pharmaceutical company headquartered in Plymouth Meeting, PA. The company was established in October 2017 with a vision to provide novel treatment options for people living with rare, neurological disorders who have unmet medical needs. For more information on Harmony Biosciences, visit
Harmony Biosciences is an Equal Opportunity, e-Verify Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
Recruitment agencies please note: Harmony Biosciences will only accept applications from agencies/business partners that have been invited to work on a specific role. Candidate Resumes/CV's submitted without permission or directly to Hiring Managers will be considered unsolicited and no fee will be payable. Thank you for your cooperation.
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Responsibilities include but are not limited to:
- Define the quality target product profile and design project plans for pre-formulation, formulation, and process development/optimization, and scale-up, in a phase-appropriate manner and execute them via contract service providers/partners.
- Lead and review drug product development activities with line management to ensure that a quality product is produced, and its manufacturing process delivers the intended performance of the product and is compliant with regulatory guidelines for Harmony's early and late-stage programs.
- Lead technical oversight of multiple Contract Organizations (COs), with the following responsibilities:
- Participate in the evaluation and selection of CDMO(s) to effectively develop, test and manufacture drug products of diverse dosage forms such as, but not limited to: oral solid, oral solution/suspension and topical.
- Design experiments to evaluate the impact of raw materials, container closure, process parameters to identify the critical formulation/process parameters and control strategies.
- Serve as technical expert on drug product aspects with particular emphasis on safety, strength, purity, quality, and product performance and associated methodologies.
- Ensure that CDMOs activities and process development activities address drug product needs for pre-clinical testing, stability, and clinical trials.
- Oversee and co-manage release testing and stability programs for drug product with Quality Assurance.
- Drive uncompromising quality as a fundamental and valued attribute of all output and patient safety as an overarching responsibility.
- Compile, review, and archive data files related to drug product activities for early and late-stage development programs, including but not limited to protocols, reports, SOPs, engineering and cGMP records, stability, and supportive documentation, etc.
- Ensure seamless transfer of knowledge and responsibilities to late-stage Process Development leads as programs progress to later stages of development
- Collaborate with other Harmony departments as required to:
- Achieve corporate goals and mission for uninterrupted clinical and commercial supply to patients.
- Monitor and manage operational budget and scope of work of CDMOs.
- Work closely with teams to define process development strategy.
- Develop and maintain technical aspects of Quality Agreements.
- Lead the execution of drug product technology transfers, support method implementation, qualification/validation.
- Work closely with Regulatory CMC to write / review drug product sections for regulatory filings.
- Bachelor's degree required within scientifically relevant field (Engineering, Chemistry, etc.), (MS / PhD is strongly preferred)
- 8+ years of relevant pharmaceutical industry experience in small molecule formulation development, process development, and product characterization across various dosage forms, including oral solids, oral liquids, or topical gels.
- Familiarity with FDA/EU and ICH guidelines for INDs/NDAs/MAAs and cGMPs.
- Experience in managing CDMOs, scientific collaborations, and contracted R&D is a plus.
- Technical proficiency in the manufacturing, packaging and interpretation of analytical and formulation testing of drug products at pilot and commercial scales, with particular emphasis on physical chemical characterization techniques to include solution and solid state stability required
- Experienced with state-of-the-art technical and compliance guidance to drive the manufacturing and data interpretation of drug products to ensure the highest quality.
- Excellent verbal, written and interpersonal communication skills, with the ability to communicate to colleagues, business partners, stakeholders and upper management and influence and coach positive behaviors across multiple contractors.
- Proficient in the use of Microsoft Office products.
- Travel (both domestic and international) is estimated to be 20% of the time for this position.
- Must be able to maintain / obtain a valid US Passport.
- While performing the duties of this job, the noise level in the work environment can vary from relatively quiet (office) to moderate (laboratory/manufacturing). Hearing protection will be required at times.
- Specific vision abilities required by this job include: close vision.
- Manual dexterity required to use computers, tablets, and cell phone.
- Continuous sitting for prolonged periods.
- Medical, Vision and Dental benefits the first of the month following start date
- Generous paid time off and Company designated Holidays
- Company paid Disability benefits and Life Insurance coverage
- 401(k) Retirement Savings Plan
- Paid Parental leave
- Employee Stock Purchase Plan (ESPP)
- Company sponsored wellness programs
- Professional development initiatives and continuous learning opportunities
- A certified Great Place to Work® for seven consecutive years based on our positive, values-based company culture
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Harmony Biosciences is a pharmaceutical company headquartered in Plymouth Meeting, PA. The company was established in October 2017 with a vision to provide novel treatment options for people living with rare, neurological disorders who have unmet medical needs. For more information on Harmony Biosciences, visit
Harmony Biosciences is an Equal Opportunity, e-Verify Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
Recruitment agencies please note: Harmony Biosciences will only accept applications from agencies/business partners that have been invited to work on a specific role. Candidate Resumes/CV's submitted without permission or directly to Hiring Managers will be considered unsolicited and no fee will be payable. Thank you for your cooperation.
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8
Senior Formulation Scientist - Novel Drug Delivery
76101 Fort Worth, Texas
$130000 Annually
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Join our client's dynamic pharmaceutical research division as a Senior Formulation Scientist, specializing in innovative drug delivery systems. This position is located in Fort Worth, Texas, US , and involves the design, development, and characterization of advanced pharmaceutical formulations. Your primary responsibilities will include developing stable and bioavailable drug products, leading pre-formulation studies, optimizing drug delivery profiles, and executing formulation development activities from concept to clinical trial readiness. You will also be involved in troubleshooting formulation challenges, preparing regulatory documentation, and staying abreast of the latest scientific advancements in pharmaceutics.
We require a Ph.D. or Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a closely related field. Significant experience (5+ years) in pharmaceutical formulation development, particularly with parenteral or oral solid dosage forms, is mandatory. Expertise in techniques such as lyophilization, microencapsulation, nano-suspensions, and solid dispersion technologies is highly desirable. Strong knowledge of drug degradation pathways, excipient compatibility, and analytical methods for characterization (HPLC, DSC, XRPD) is essential. Excellent leadership, communication, and project management skills are required to guide formulation projects and collaborate with R&D, manufacturing, and regulatory affairs teams. This role offers a chance to contribute to the development of life-changing therapies in a collaborative and innovative environment, with a competitive compensation and benefits package.
We require a Ph.D. or Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a closely related field. Significant experience (5+ years) in pharmaceutical formulation development, particularly with parenteral or oral solid dosage forms, is mandatory. Expertise in techniques such as lyophilization, microencapsulation, nano-suspensions, and solid dispersion technologies is highly desirable. Strong knowledge of drug degradation pathways, excipient compatibility, and analytical methods for characterization (HPLC, DSC, XRPD) is essential. Excellent leadership, communication, and project management skills are required to guide formulation projects and collaborate with R&D, manufacturing, and regulatory affairs teams. This role offers a chance to contribute to the development of life-changing therapies in a collaborative and innovative environment, with a competitive compensation and benefits package.
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