17 Drug Formulation jobs in the United States
Principal Pharmaceutical Scientist - Drug Formulation
78245 San Antonio, Texas
$145000 Annually
WhatJobs
Posted 8 days ago
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Job Description
Our client is seeking a highly accomplished Principal Pharmaceutical Scientist to lead innovative drug formulation research and development in **San Antonio, Texas, US**. This senior position is critical in advancing our pipeline of novel therapeutics from early-stage development through to commercialization. The successful candidate will possess deep expertise in solid dosage forms, sterile injectables, or other advanced drug delivery systems. You will be responsible for designing, executing, and interpreting complex formulation studies, troubleshooting formulation challenges, and ensuring compliance with regulatory guidelines.
Key responsibilities include leading formulation development projects, defining critical quality attributes (CQAs) and critical process parameters (CPPs), and overseeing scale-up activities from lab to pilot plant. You will collaborate closely with analytical chemists, process engineers, regulatory affairs specialists, and manufacturing teams to ensure successful drug product development. This role involves extensive literature review, patent analysis, and staying current with the latest scientific advancements in pharmaceutical sciences. Mentoring junior scientists, contributing to strategic R&D planning, and presenting findings to senior management and external stakeholders are also key aspects of this position.
The ideal candidate will hold a Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, or a related discipline. A minimum of 8-10 years of progressive experience in pharmaceutical R&D, with a strong focus on drug formulation and product development, is required. Demonstrated expertise in preclinical and clinical formulation development, including experience with various dosage forms and delivery technologies, is essential. Strong understanding of GMP, ICH guidelines, and regulatory submission requirements (IND, NDA) is mandatory. Excellent analytical, problem-solving, and project management skills are paramount. Exceptional communication and interpersonal skills are required for effective collaboration within a multidisciplinary team environment. This is an on-site position in **San Antonio, Texas, US**.
Key responsibilities include leading formulation development projects, defining critical quality attributes (CQAs) and critical process parameters (CPPs), and overseeing scale-up activities from lab to pilot plant. You will collaborate closely with analytical chemists, process engineers, regulatory affairs specialists, and manufacturing teams to ensure successful drug product development. This role involves extensive literature review, patent analysis, and staying current with the latest scientific advancements in pharmaceutical sciences. Mentoring junior scientists, contributing to strategic R&D planning, and presenting findings to senior management and external stakeholders are also key aspects of this position.
The ideal candidate will hold a Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemical Engineering, or a related discipline. A minimum of 8-10 years of progressive experience in pharmaceutical R&D, with a strong focus on drug formulation and product development, is required. Demonstrated expertise in preclinical and clinical formulation development, including experience with various dosage forms and delivery technologies, is essential. Strong understanding of GMP, ICH guidelines, and regulatory submission requirements (IND, NDA) is mandatory. Excellent analytical, problem-solving, and project management skills are paramount. Exceptional communication and interpersonal skills are required for effective collaboration within a multidisciplinary team environment. This is an on-site position in **San Antonio, Texas, US**.
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0
Principal Pharmaceutical Development Scientist - Drug Formulation
53705 Madison, Wisconsin
$160000 Annually
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Posted 8 days ago
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Job Description
Our client is seeking a highly accomplished and innovative Principal Pharmaceutical Development Scientist specializing in drug formulation to join their leading R&D team. This senior-level position will play a crucial role in the discovery and development of novel drug delivery systems and dosage forms for a range of therapeutic areas. You will lead formulation development projects from early-stage concept through to preclinical and clinical evaluation, driving scientific excellence and strategic decision-making. The ideal candidate will possess a deep understanding of pharmaceutics, excipient science, and drug product manufacturing processes.
Responsibilities:
Responsibilities:
- Lead the formulation development of new drug candidates, including small molecules, biologics, or other therapeutic modalities.
- Design and execute experiments to characterize drug substances and develop robust, stable, and bioavailable drug product formulations (e.g., tablets, capsules, injectables, topical).
- Investigate and select appropriate excipients, considering drug properties, desired release profiles, and manufacturing feasibility.
- Develop and validate analytical methods for assessing drug product quality, stability, and performance.
- Conduct pre-formulation studies, including solubility, stability, and compatibility assessments.
- Oversee formulation scale-up activities and technology transfer to manufacturing sites.
- Collaborate closely with analytical chemistry, process development, regulatory affairs, and clinical teams.
- Interpret complex data, draw scientifically sound conclusions, and present findings to internal stakeholders and leadership.
- Stay abreast of the latest scientific literature, industry trends, and regulatory guidelines in pharmaceutical development and formulation.
- Mentor and guide junior scientists and contribute to the overall scientific strategy of the department.
- Author relevant sections of regulatory filings (e.g., IND, NDA).
- Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field.
- Minimum of 10 years of experience in pharmaceutical drug product development, with a strong focus on formulation science.
- Extensive hands-on experience with various dosage forms and drug delivery technologies.
- Deep knowledge of physical chemistry, materials science, and biopharmaceutics related to drug formulation.
- Proven experience in leading formulation development projects from discovery through to late-stage development.
- Proficiency with formulation development and analytical instrumentation (e.g., HPLC, dissolution testers, DSC, TGA).
- Excellent problem-solving, critical thinking, and experimental design skills.
- Exceptional communication, presentation, and interpersonal skills, with the ability to influence scientific direction.
- Experience working in a hybrid R&D environment, balancing remote analysis and collaboration with on-site laboratory work.
- A strong publication record or patent history is a plus.
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1
Principal Scientist - Drug Discovery & Formulation
53703 Madison, Wisconsin
$165000 Annually
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Posted 6 days ago
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Job Description
Our client, a dynamic biopharmaceutical company situated in **Madison, Wisconsin, US**, is seeking a highly accomplished Principal Scientist to lead critical initiatives in Drug Discovery and Formulation. This senior research position is central to our mission of developing innovative therapeutics for unmet medical needs. You will be responsible for driving the early-stage discovery pipeline, from target identification and validation through lead optimization and pre-formulation studies. This role requires a deep scientific understanding of disease biology, medicinal chemistry, and drug delivery systems, coupled with extensive experience in guiding research projects and mentoring scientific staff. The ideal candidate will possess a strong publication record and a proven ability to translate complex scientific concepts into actionable research strategies.
Responsibilities:
Responsibilities:
- Lead and execute multidisciplinary research programs focused on novel drug discovery.
- Design and implement strategies for target identification, validation, and assay development.
- Oversee medicinal chemistry efforts for lead generation and optimization, collaborating with external partners.
- Develop and characterize novel drug delivery systems and formulation strategies to enhance bioavailability and efficacy.
- Utilize advanced analytical techniques (e.g., HPLC, MS, NMR) for compound characterization and purity assessment.
- Manage external collaborations with academic institutions and contract research organizations (CROs).
- Interpret complex biological and chemical data to guide research direction and decision-making.
- Prepare scientific reports, regulatory documents, and grant proposals.
- Present research findings at internal reviews and external scientific conferences.
- Mentor and supervise a team of research scientists and technicians.
- Ph.D. in Pharmacology, Medicinal Chemistry, Biochemistry, Pharmaceutical Sciences, or a related discipline.
- 10+ years of post-doctoral or industry experience in pharmaceutical drug discovery.
- Proven expertise in small molecule drug discovery, assay development, and lead optimization.
- Demonstrated experience in formulation development and drug delivery technologies.
- Strong understanding of pharmacokinetics (PK), pharmacodynamics (PD), and toxicology principles.
- Excellent leadership, project management, and communication skills.
- A track record of successful project progression and publications in reputable scientific journals.
- Experience with biologics discovery is a plus.
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2
Senior Formulation Scientist, Drug Development
78701 Austin, Texas
$130000 Annually
WhatJobs
Posted 6 days ago
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Job Description
Our client, a leading pharmaceutical innovator, is seeking a highly skilled and experienced Senior Formulation Scientist to join their dynamic Drug Development team in Austin, Texas, US . This role is crucial in advancing our pipeline from pre-clinical to clinical stages, focusing on developing robust and scalable drug delivery systems. The ideal candidate will possess a deep understanding of pharmaceutics, solid dosage forms, and advanced drug delivery technologies. You will be responsible for designing, executing, and interpreting formulation development studies, troubleshooting technical challenges, and contributing to regulatory filings. This will involve extensive hands-on laboratory work, including pre-formulation characterization, excipient screening, prototype formulation development, process optimization, and stability testing. You will collaborate closely with cross-functional teams, including analytical chemistry, process development, and clinical operations, to ensure seamless project progression. Key responsibilities include developing formulations for oral solid dosage forms (tablets, capsules), evaluating drug solubility and stability, selecting appropriate excipients and manufacturing processes, and scaling up formulations from lab bench to pilot scale. A strong commitment to Good Manufacturing Practices (GMP) and Good Laboratory Practices (GLP) is essential. The successful candidate will also mentor junior scientists, contribute to intellectual property generation, and stay abreast of the latest scientific advancements in pharmaceutical formulation. A Ph.D. or Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field, coupled with at least 5 years of relevant industry experience, is required. Excellent analytical, problem-solving, and communication skills are paramount for success in this challenging and rewarding position.
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3
Senior Formulation Scientist - Drug Development
27701 Durham, North Carolina
$135000 Annually
WhatJobs
Posted 7 days ago
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Job Description
Our client, a leading pharmaceutical company dedicated to improving global health, is seeking an accomplished Senior Formulation Scientist to join their innovative research and development team. This is a vital, in-office position located in the heart of the thriving pharmaceutical hub of Durham, North Carolina, US . The Senior Formulation Scientist will be instrumental in the design, development, and optimization of novel drug delivery systems and dosage forms. You will leverage your extensive scientific expertise to guide projects from early-stage feasibility through to late-stage clinical development, ensuring the successful translation of promising drug candidates into safe and effective therapies.
Key Responsibilities:
Key Responsibilities:
- Lead the formulation development of various dosage forms, including oral solid, liquid, semi-solid, and injectable products.
- Design and execute experiments to investigate drug solubility, stability, bioavailability, and release profiles.
- Utilize DoE (Design of Experiments) principles to optimize formulations and manufacturing processes.
- Characterize drug products using a range of analytical techniques (e.g., HPLC, dissolution testing, DSC, XRD).
- Develop and validate analytical methods for formulation testing and release testing.
- Prepare comprehensive technical reports, development summaries, and regulatory submission documents.
- Collaborate with cross-functional teams, including pre-clinical, clinical, analytical development, and manufacturing departments.
- Troubleshoot formulation and process-related issues, proposing and implementing effective solutions.
- Evaluate new excipients, technologies, and manufacturing processes relevant to drug formulation.
- Mentor junior scientists and contribute to the growth and development of the formulation sciences team.
- Stay current with regulatory guidelines (FDA, EMA) and industry best practices in pharmaceutical development.
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4
Lead Formulation Scientist, Drug Development
75201 Prairie View, Texas
$150000 Annually
WhatJobs
Posted 8 days ago
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Job Description
A pioneering pharmaceutical company focused on developing novel therapeutics is seeking an exceptional Lead Formulation Scientist to join their cutting-edge, fully remote research and development team. This critical role will drive the formulation development of new drug candidates, from preclinical stages through to clinical trials. You will be responsible for designing, optimizing, and characterizing various drug delivery systems, ensuring bioavailability, stability, and efficacy. The ideal candidate will possess extensive expertise in pharmaceutical sciences, with a strong background in pre-formulation studies, solid dosage forms, sterile injectables, or other relevant areas. Your responsibilities will include conducting extensive literature reviews, developing experimental plans, executing laboratory experiments, and analyzing data to select optimal formulations. You will collaborate closely with discovery scientists, analytical chemists, and project managers to advance drug candidates through the pipeline. This position requires a deep understanding of regulatory requirements (e.g., FDA, EMA) and the ability to translate scientific findings into robust formulation strategies. You will also be involved in troubleshooting formulation challenges and contributing to the intellectual property strategy of the company. This is a unique opportunity for a highly skilled and motivated scientist to lead impactful formulation projects in a dynamic, remote-first environment, contributing to the development of life-changing medicines.Responsibilities:
- Lead and execute formulation development strategies for new drug candidates.
- Design and optimize drug delivery systems (e.g., oral solids, injectables, topical).
- Conduct pre-formulation studies to assess drug properties and compatibility.
- Develop and validate analytical methods for formulation characterization.
- Perform stability studies and interpret results to ensure product integrity.
- Troubleshoot formulation challenges and propose innovative solutions.
- Collaborate with cross-functional teams, including analytical development, pharmacology, and CMC.
- Prepare technical reports, development summaries, and regulatory submission documents.
- Stay abreast of scientific advancements and regulatory guidelines in pharmaceutical formulation.
- Contribute to the intellectual property portfolio through patent filings.
- Ph.D. in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field.
- Minimum of 8 years of experience in pharmaceutical formulation development.
- Proven expertise in drug delivery technologies and formulation design.
- Strong understanding of pre-formulation, analytical techniques, and stability testing.
- Experience with regulatory requirements for drug development (IND, NDA).
- Excellent data analysis, problem-solving, and critical thinking skills.
- Strong written and verbal communication skills.
- Ability to work independently and lead research projects in a remote setting.
- Experience with LIMS and electronic lab notebooks is a plus.
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5
Senior Formulation Scientist, Drug Development
46201 Indianapolis, Indiana
$135000 Annually
WhatJobs
Posted 8 days ago
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Job Description
Our client, a leading pharmaceutical company, is seeking an accomplished Senior Formulation Scientist to join their dedicated Research & Development team in Indianapolis, Indiana, US . This role is integral to the design, development, and optimization of innovative drug formulations that enhance patient outcomes. The ideal candidate will possess a deep understanding of pharmaceutical sciences, extensive experience in dosage form development, and a strong commitment to scientific rigor. You will be responsible for leading formulation projects, collaborating with analytical and pre-clinical teams, and ensuring timely progression through the drug development pipeline.
Key Responsibilities:
Qualifications:
Key Responsibilities:
- Designing and developing novel oral solid dosage forms (tablets, capsules) and potentially other dosage forms (e.g., injectables, topicals).
- Conducting pre-formulation studies to characterize drug substances and excipients.
- Developing and optimizing formulations to meet desired pharmacokinetic profiles, stability requirements, and manufacturability targets.
- Performing solubility enhancement, particle engineering, and solid-state characterization studies.
- Collaborating closely with analytical development teams to establish appropriate testing methods and specifications.
- Supporting formulation scale-up activities and technology transfer to manufacturing.
- Investigating and resolving formulation-related challenges encountered during development.
- Authoring and reviewing formulation development reports, protocols, and regulatory submission documents.
- Staying updated on industry trends, new technologies, and regulatory guidelines relevant to formulation development.
- Mentoring junior scientists and contributing to a collaborative team environment.
- Participating in cross-functional project teams, providing formulation expertise.
- Ensuring compliance with Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP).
Qualifications:
- Ph.D. or Master's degree in Pharmaceutical Sciences, Pharmaceutics, Chemistry, or a related field.
- Minimum of 5-7 years of progressive experience in pharmaceutical formulation development.
- Proven expertise in the development of various dosage forms, with a strong emphasis on oral solids.
- Hands-on experience with formulation equipment and analytical techniques (e.g., HPLC, DSC, TGA, XRPD).
- Understanding of drug delivery principles, pharmacokinetics, and biopharmaceutics.
- Familiarity with regulatory requirements (FDA, EMA) for drug product development.
- Excellent problem-solving, critical thinking, and data interpretation skills.
- Strong written and verbal communication skills, with the ability to present scientific data effectively.
- Ability to work independently and collaboratively in a fast-paced research environment.
- Experience with process development and manufacturing is desirable.
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6
Senior Formulation Scientist - Drug Development
30303 Atlanta, Georgia
$140000 Annually
WhatJobs
Posted 8 days ago
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Job Description
Our client, a leading pharmaceutical innovator, is seeking a highly skilled and experienced Senior Formulation Scientist to join their esteemed fully remote drug development team. This pivotal role is responsible for the design, development, and optimization of novel drug delivery systems and formulations for a range of therapeutic agents. The ideal candidate will possess a deep understanding of pharmaceutical sciences, including drug solubility, stability, bioavailability, and excipient selection, with a proven track record in pre-formulation and formulation development. You will be responsible for leading formulation projects, conducting experimental studies, analyzing data, and troubleshooting formulation challenges to ensure the successful progression of drug candidates through the development pipeline. This remote position requires exceptional scientific rigor, strong problem-solving abilities, and excellent communication skills to collaborate effectively with internal teams and external partners. Responsibilities include: developing oral solid dosage forms, injectable formulations, and topical preparations; characterizing formulations using various analytical techniques (HPLC, DSC, XRPD, etc.); performing stability studies according to ICH guidelines; and contributing to regulatory filings (IND, NDA). You will also stay abreast of emerging formulation technologies and regulatory requirements. This is a unique opportunity to contribute significantly to the development of life-changing medicines from a remote location, working with a dynamic team dedicated to scientific excellence and patient well-being. Your expertise in pharmaceutical formulation will be critical in bringing innovative therapies to market.
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7
Senior Formulation Scientist, Drug Development
81007 Colorado Springs, Colorado
$140000 Annually
WhatJobs
Posted 8 days ago
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Job Description
Our client is a leading pharmaceutical company seeking a highly skilled Senior Formulation Scientist to join their innovative Drug Development team. This role, based in Colorado Springs, Colorado, US , operates on a hybrid model, combining critical laboratory work with flexible remote collaboration. The ideal candidate will have a deep understanding of pharmaceutical formulation science and a proven ability to develop stable, effective, and manufacturable drug products. You will be responsible for the formulation development of new chemical entities (NCEs) and the lifecycle management of existing products, encompassing various dosage forms.
Key responsibilities include designing and executing pre-formulation studies, developing prototype formulations, and optimizing formulations to meet target product profiles. This involves extensive hands-on laboratory work, including excipient screening, stability testing, dissolution profiling, and analytical method development/validation. You will also be involved in scale-up activities, troubleshooting manufacturing processes, and ensuring compliance with regulatory requirements (e.g., FDA, EMA). The Senior Formulation Scientist will work closely with cross-functional teams, including analytical development, process chemistry, regulatory affairs, and clinical operations, to advance projects through the development pipeline. Strong communication and interpersonal skills are essential for effectively collaborating with internal stakeholders and external partners.
A Master's or Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field is required, along with a minimum of 5-7 years of relevant industry experience in formulation development. Experience with various dosage forms (e.g., oral solids, injectables, topicals) is highly desirable. Proficiency in laboratory techniques and analytical instrumentation is a must. The ability to critically analyze data, solve complex problems, and contribute to scientific publications and regulatory submissions is expected. If you are a motivated scientist eager to contribute to the development of life-changing medicines in a dynamic, hybrid work environment, we encourage you to apply.
Key responsibilities include designing and executing pre-formulation studies, developing prototype formulations, and optimizing formulations to meet target product profiles. This involves extensive hands-on laboratory work, including excipient screening, stability testing, dissolution profiling, and analytical method development/validation. You will also be involved in scale-up activities, troubleshooting manufacturing processes, and ensuring compliance with regulatory requirements (e.g., FDA, EMA). The Senior Formulation Scientist will work closely with cross-functional teams, including analytical development, process chemistry, regulatory affairs, and clinical operations, to advance projects through the development pipeline. Strong communication and interpersonal skills are essential for effectively collaborating with internal stakeholders and external partners.
A Master's or Ph.D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field is required, along with a minimum of 5-7 years of relevant industry experience in formulation development. Experience with various dosage forms (e.g., oral solids, injectables, topicals) is highly desirable. Proficiency in laboratory techniques and analytical instrumentation is a must. The ability to critically analyze data, solve complex problems, and contribute to scientific publications and regulatory submissions is expected. If you are a motivated scientist eager to contribute to the development of life-changing medicines in a dynamic, hybrid work environment, we encourage you to apply.
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8
Senior Formulation Scientist - Drug Development
32201 Riverview, Florida
$125000 Annually
WhatJobs
Posted 8 days ago
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Job Description
Our client, a rapidly growing biopharmaceutical company at the forefront of developing novel therapeutics, is seeking an accomplished Senior Formulation Scientist to join their R&D team in **Jacksonville, Florida, US**. This critical role will focus on the design, development, and optimization of innovative drug formulations to enhance efficacy, safety, and patient compliance. You will be responsible for the formulation development of small molecules and/or biologics, from early-stage pre-formulation studies through to late-stage clinical development and commercialization. This involves conducting physicochemical characterization, determining optimal excipient compositions, and developing robust manufacturing processes. Responsibilities include executing experimental studies, analyzing results, and documenting findings in comprehensive reports suitable for regulatory submissions. The Senior Formulation Scientist will collaborate closely with discovery, analytical development, manufacturing, and regulatory affairs teams to ensure seamless project progression. You will play a key role in troubleshooting formulation challenges, identifying root causes, and implementing effective solutions. This position requires a deep understanding of pharmaceutics, materials science, and drug delivery systems. A proactive approach to problem-solving, strong experimental design skills, and the ability to interpret complex scientific data are essential. You will also contribute to the intellectual property strategy and stay abreast of emerging trends and technologies in drug formulation and delivery. This role offers a significant opportunity to contribute to the development of life-changing medicines within a stimulating and collaborative scientific environment.
Key Responsibilities:
Qualifications:
Key Responsibilities:
- Design and develop stable, effective, and scalable drug formulations (e.g., oral solid dosage forms, injectables, topical).
- Conduct pre-formulation studies, including physicochemical characterization of drug substances and excipients.
- Optimize formulation compositions and manufacturing processes to meet target product profiles.
- Develop and validate analytical methods for formulation characterization and quality control.
- Execute experimental plans, analyze data, and prepare comprehensive study reports.
- Collaborate with analytical development, process engineering, and regulatory affairs teams.
- Troubleshoot formulation and manufacturing issues, identifying root causes and implementing solutions.
- Evaluate and implement new formulation technologies and delivery systems.
- Contribute to the preparation of CMC sections for regulatory submissions (e.g., IND, NDA).
- Stay informed about scientific literature, industry trends, and regulatory guidelines in pharmaceutics.
Qualifications:
- Ph.D. or Master's degree in Pharmaceutical Sciences, Chemical Engineering, Chemistry, or a related discipline.
- Minimum of 5 years of hands-on experience in pharmaceutical formulation development.
- Proven track record in developing various dosage forms, preferably for small molecules or biologics.
- Strong understanding of physical chemistry, materials science, and drug delivery principles.
- Proficiency in formulation characterization techniques (e.g., DSC, TGA, XRPD, spectroscopy).
- Experience with analytical techniques commonly used in pharmaceutical analysis (e.g., HPLC, GC, dissolution).
- Excellent problem-solving, analytical, and critical thinking skills.
- Strong written and verbal communication skills, with experience in report writing and presentation.
- Ability to work independently and as part of a multidisciplinary team.
- Familiarity with GMP guidelines and regulatory requirements.
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