165 Molecular Biology jobs in the United States

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at Function:**
Discovery & Pre-Clinical/Clinical Development
**Job Sub** **Function:**
Biotherapeutics R&D
**Job Category:**
Scientific/Technology
**All Job Posting Locations:**
Spring House, Pennsylvania, United States of America
**Job Description:**
**About Innovative Medicine:**
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at are searching for the best talent for a Principal Scientist, Molecular Biology** **to be onsite in Spring House, PA.**
**Purpose:**
The _in Vivo_ Antibody Discovery group within Biologics Discovery is responsible for lead antibody generation from immunized animals with state-of-the-art technologies including single B cell sorting, hybridoma, display and microfluidics. In this key role, the Principal Scientist will **lead a team responsible for** **recovery of antibody sequences from selected hybridoma cells or single B cells** . The candidate is expected to work with automation experts to automate NGS workflow for efficient sequence recovery. In-depth knowledge and extensive experience in molecular cloning of BCR using various approaches including RT-PCR, Topo cloning, in-fusion cloning, multiplex NGS, 10X genomics are required. A strong understanding of B-cell recovery methods such as Hybridoma technology and primary B-cell cloning will also be important. This is a critical function in a multifaceted Biologics Discovery organization committed to bringing the next generation of biotherapeutic molecules to patients. We are looking for a motivated candidate with scientific and technical expertise who can collaborate across discovery areas to bring value to our portfolio of innovative drug concepts. Proficiency to work within a highly coordinated, fast-paced environment will be a significant attribute. If this sounds like you, come join our team!
**You will be responsible for** **:**
+ Provide day-to-day in-person guidance and mentoring within the V-Gene Recovery (VGR) team
+ Lead antibody sequence recovery from selected hits of diverse sources, including hybridoma, single B cells, immune repertoires, and in vitro display platforms.
+ Execute and optimize molecular biology workflows, including Next-Generation Sequencing (NGS) and conventional Sanger sequencing, to enable efficient and accurate antibody discovery.
+ Work with automation experts to automate and streamline NGS workflows, identifying opportunities for process improvements to enhance sequencing accuracy and efficiency.
+ Manage laboratory operations by maintaining equipment, ensuring sufficient inventory of supplies, and overseeing the routine maintenance of NGS instruments and related laboratory equipment.
+ Conduct comprehensive data analysis, interpret sequencing results, and generate detailed reports. Bioinformatics experience is a plus.
+ Present research findings in internal meetings, clearly communicating scientific results and providing insights into data interpretation.
+ Collaborate with multidisciplinary teams across functional areas to advance therapeutic programs, contributing scientific expertise to multiple projects in a dynamic and fast-paced environment.
+ Document work accurately and promptly using Electronic Lab Notebook systems (e.g., Signal) and generate protocols and SOPs.
+ Work closely with stakeholders and project managers to address operational needs and ensure seamless workflow execution.
+ Demonstrate scientific curiosity and problem-solving skills, contributing to innovation and continuous improvement in molecular biology and sequencing workflows.
**Qualifications / Requirements:**
**Education and Years of Experience:**
+ Minimum of a Bachelor's degree is required
+ PhD in Molecular Biology, Biomedical Engineering, Biochemistry or a related field is highly preferred
**Required:**
+ Minimum 6 years of experience in the pharmaceutical industry and/or academic setting
+ Team management experience
+ Proficiency in molecular biology techniques, including PCR, molecular cloning, and plasmid design.
+ Expertise with DNA sequencing (NGS, 10x Genomics, Sanger) and sequence data analysis related to antibody discovery.
**Preferred:**
+ Familiarity with techniques for antibody repertoire analysis and single cell analysis.
+ Knowledge of data management and visualization tools for large datasets, and knowledge with statistical analysis of NGS results.
+ Knowledge on leveraging repertoire sequencing from immunized animals for AI/ML-driven antibody discovery
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via , internal employees contact AskGS to be directed to your accommodation resource.
#LI-Onsite

**Molecular Biology Research Associate**
Durham, NC | Contract | Onsite Lab Role
**Position Overview:**
We're hiring a **Research Associate** with hands-on experience in **molecular biology** to support discovery research at **a lab** providing essential inputs to growers: crop protection, seeds, seed treatments and traits in **Durham, NC** . This is an **onsite** , full-time position with the potential for permanent hire.
**Key Responsibilities:**
+ Perform **PCR** , **cloning** , **E. coli transformation** , and **plasmid prep**
+ Conduct **gel electrophoresis** , **bacterial culturing** , and **DNA purification**
+ Support plant infiltrations and use LIMS for data tracking
+ Collaborate in a fast-paced lab environment and maintain accurate records
**Qualifications:**
+ **BS in Molecular Biology** , Microbiology, or related field
+ **1+ year lab experience** with molecular techniques
+ Strong aseptic technique and attention to detail
+ Experience with automated liquid handling is a plus
**Job Details:**
+ **Location:** Onsite in Durham, NC
+ **Schedule:** Mon-Fri, Full-Time
+ **Pay:** $30/hr.
**Apply Now**
Submit your resume to be considered. Qualified candidates will be contacted promptly.
**Pay Details:** $30.00 per hour
Benefit offerings available for our associates include medical, dental, vision, life insurance, short-term disability, additional voluntary benefits, EAP program, commuter benefits and a 401K plan. Our benefit offerings provide employees the flexibility to choose the type of coverage that meets their individual needs. In addition, our associates may be eligible for paid leave including Paid Sick Leave or any other paid leave required by Federal, State, or local law, as well as Holiday pay where applicable.
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**Massachusetts Candidates Only:** It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Our client is a highly innovative biotechnology firm dedicated to advancing scientific discovery and is seeking a Principal Scientist with expertise in Molecular Biology to join their state-of-the-art research and development facility in Omaha, Nebraska, US . This senior-level position will play a critical role in designing and executing complex research projects, leading scientific teams, and contributing to the development of novel therapeutic strategies. The ideal candidate will possess a deep understanding of molecular mechanisms underlying disease, advanced experimental techniques, and a strong publication record in peer-reviewed journals. You will be responsible for conceptualizing and implementing cutting-edge research programs, mentoring junior scientists, and collaborating with cross-functional teams to advance projects from discovery through preclinical development. Your responsibilities will include designing and conducting experiments involving gene expression analysis, protein-protein interactions, cell signaling pathways, and genetic manipulation. You will analyze and interpret complex data sets, present findings to internal and external stakeholders, and contribute to intellectual property development. We are looking for a visionary scientist with exceptional problem-solving skills, a rigorous scientific approach, and a passion for translating fundamental research into impactful solutions. This role offers a significant opportunity to lead scientific innovation and shape the future of drug discovery within a dynamic and collaborative research environment.

Key Responsibilities:

• Lead the design, execution, and interpretation of complex molecular biology research projects.
• Develop and implement innovative experimental strategies to address key scientific questions.
• Mentor and guide junior scientists and research associates, fostering a collaborative and productive research environment.
• Analyze and troubleshoot experimental data, ensuring scientific rigor and reproducibility.
• Prepare and present research findings at internal meetings and external scientific conferences.
• Contribute to the development of intellectual property through patent applications and scientific publications.
• Collaborate closely with other departments, including chemistry, pharmacology, and toxicology, to advance drug discovery programs.
• Stay abreast of the latest scientific literature, technologies, and methodologies in molecular biology and related fields.
• Contribute to the strategic direction of the R&D department.

Qualifications:

• Ph.D. in Molecular Biology, Biochemistry, Cell Biology, or a related field.
• Minimum of 8 years of post-doctoral and/or industry research experience, with a strong focus on molecular mechanisms of disease.
• Proven track record of independent research and significant contributions to the field, evidenced by high-impact publications.
• Extensive hands-on experience with a wide range of molecular biology techniques, including qPCR, Western blotting, ELISA, cloning, CRISPR, and cell-based assays.
• Experience in leading research projects and mentoring junior scientists.
• Excellent analytical, problem-solving, and critical thinking skills.
• Strong written and verbal communication skills for effective presentation of scientific data.
• Ability to work effectively in a collaborative, team-oriented research environment.
• Experience with bioinformatics tools and analysis is a plus.

Our client is seeking a dedicated and innovative Research Scientist specializing in Molecular Biology to join their cutting-edge research facility in Boise, Idaho, US . This role is essential for driving forward novel research projects and contributing to significant scientific discoveries. You will be responsible for designing and executing experiments, analyzing data, and collaborating with a multidisciplinary team of scientists. This position offers a unique opportunity to work on impactful projects in a state-of-the-art laboratory environment.

Responsibilities:

• Design, plan, and execute complex molecular biology experiments using a variety of techniques (e.g., PCR, qPCR, Western blotting, DNA sequencing, cell culture).
• Analyze experimental data using appropriate statistical and bioinformatics tools.
• Interpret results and draw scientifically sound conclusions.
• Troubleshoot experimental issues and optimize protocols.
• Maintain accurate and detailed laboratory records and documentation.
• Collaborate with other scientists and researchers to share findings and contribute to project goals.
• Prepare manuscripts for publication in peer-reviewed journals and present research at scientific conferences.
• Stay current with the latest advancements and methodologies in molecular biology and related fields.
• Order and manage laboratory supplies and reagents.
• Contribute to grant writing and funding proposals.

Qualifications:

• Ph.D. in Molecular Biology, Biochemistry, Genetics, or a related life science discipline.
• 3+ years of post-doctoral or industry research experience in molecular biology.
• Proven expertise in a broad range of molecular biology techniques.
• Strong understanding of molecular biology principles, cellular processes, and genetic mechanisms.
• Experience with bioinformatics tools and data analysis software.
• Excellent critical thinking, problem-solving, and analytical skills.
• Strong written and oral communication skills, with a track record of scientific publications.
• Ability to work independently and effectively as part of a collaborative research team.
• Experience with microscopy techniques is a plus.
• Proficiency in relevant laboratory software and data management systems.

This is an exceptional opportunity to contribute to significant research and development efforts within a dynamic scientific community. Our client offers a competitive salary, comprehensive benefits, and a supportive work environment that fosters scientific growth and innovation.

Our client, a world-renowned research institution dedicated to pioneering scientific discoveries, is seeking an accomplished Senior Scientist to join their Molecular Biology department in Washington, D.C. This role is crucial for advancing cutting-edge research in understanding cellular mechanisms and developing novel therapeutic strategies. The Senior Scientist will lead research projects, mentor junior staff, design and execute complex experiments, and contribute significantly to publications and grant applications. The ideal candidate possesses a deep understanding of molecular biology techniques, strong analytical skills, and a passion for scientific innovation.

Key Responsibilities:

• Design, execute, and interpret complex experiments in molecular and cellular biology.
• Lead independent research projects from conception to completion, including hypothesis generation, experimental design, data analysis, and reporting.
• Develop and optimize novel molecular and cellular assays.
• Troubleshoot experimental procedures and instrumentation.
• Analyze and interpret large datasets using appropriate statistical methods.
• Prepare manuscripts for publication in high-impact scientific journals.
• Present research findings at national and international scientific conferences.
• Mentor and train junior scientists, postdocs, and technicians in laboratory techniques and research methodologies.
• Contribute to the writing of grant proposals to secure funding for research projects.
• Maintain accurate laboratory notebooks and records.
• Collaborate effectively with internal and external research groups.
• Ensure compliance with all safety regulations and laboratory protocols.

Qualifications:

• Ph.D. in Molecular Biology, Cell Biology, Biochemistry, or a closely related field.
• Minimum of 5 years of postdoctoral research experience, demonstrating a strong publication record.
• Extensive hands-on experience with a wide range of molecular biology techniques (e.g., PCR, qPCR, Western blotting, cloning, gene editing, cell culture, microscopy).
• Proven experience in leading research projects and mentoring junior staff.
• Strong understanding of scientific principles and experimental design.
• Excellent analytical, critical thinking, and problem-solving skills.
• Proficiency in data analysis software (e.g., GraphPad Prism, R).
• Excellent written and verbal communication skills, with experience in scientific writing and presentation.
• Ability to work independently and collaboratively in a research-intensive environment.
• Must be based in or willing to relocate to the Washington, D.C. area.

This position offers an exceptional opportunity to conduct impactful research at the forefront of molecular biology.

Our client is seeking a highly accomplished Principal Scientist with expertise in Molecular Biology to join their groundbreaking research and development team in Sacramento, California, US . This senior role is crucial for driving innovative research, developing novel methodologies, and leading complex scientific projects from conception through to experimental validation. The ideal candidate will possess a Ph.D. in Molecular Biology or a related field, coupled with extensive post-doctoral and industry experience. You will be responsible for designing and executing experiments, interpreting complex data sets, and contributing to scientific publications and patent applications. This position requires a deep understanding of cutting-edge molecular biology techniques, including genomics, transcriptomics, proteomics, and gene editing technologies. The Principal Scientist will mentor junior researchers, collaborate with interdisciplinary teams, and present research findings to internal and external audiences. A strong track record of independent research, successful grant writing, and a passion for scientific discovery are essential. You will play a key role in shaping the scientific direction of research programs and contributing to the company's strategic goals. We are looking for a visionary leader with exceptional scientific acumen and a commitment to advancing knowledge in the field.

Responsibilities:

• Design, develop, and execute complex research projects in molecular biology.
• Lead the interpretation of experimental data and draw robust scientific conclusions.
• Develop and optimize novel molecular biology assays and protocols.
• Mentor and guide junior scientists and research associates.
• Collaborate with cross-functional teams to achieve research objectives.
• Contribute to the preparation of scientific manuscripts, reports, and patent applications.
• Present research findings at scientific conferences and internal meetings.
• Stay abreast of the latest advancements and emerging technologies in molecular biology.
• Manage laboratory resources, including equipment and supplies.
• Contribute to strategic planning and prioritization of research initiatives.

Qualifications:

• Ph.D. in Molecular Biology, Genetics, Biochemistry, or a closely related field.
• Minimum of 7-10 years of relevant research experience post-Ph.D., including significant experience in a leadership or principal investigator role.
• Extensive hands-on experience with a wide range of molecular biology techniques (e.g., PCR, qPCR, Western blotting, ELISA, next-generation sequencing, CRISPR).
• Proven track record of scientific innovation, publications in high-impact journals, and conference presentations.
• Demonstrated ability to design and conduct complex experiments and analyze data rigorously.
• Strong understanding of experimental design and statistical analysis.
• Excellent leadership, communication, and interpersonal skills.
• Ability to work independently and as part of a collaborative research team.
• Experience with bioinformatics tools and data analysis is a plus.
• Proficiency in managing laboratory operations and mentoring junior staff.

Our client, a cutting-edge biomedical research institution, is seeking a highly accomplished Principal Scientist in Molecular Biology to lead groundbreaking research initiatives in Baltimore, Maryland, US . This senior role demands a visionary leader with a profound understanding of molecular mechanisms and a proven ability to drive scientific discovery from bench to bedside. The successful candidate will spearhead research projects, mentor a team of talented scientists, and contribute to the institution's reputation for scientific excellence. This position offers a hybrid work arrangement, allowing for flexibility while maintaining essential on-site laboratory presence.

Key responsibilities include:

• Designing, executing, and interpreting complex experiments in molecular biology, genomics, and proteomics.
• Developing and optimizing novel research methodologies and assays.
• Leading and mentoring a team of postdoctoral fellows, research associates, and technicians.
• Securing external funding through grant writing and proposal development.
• Collaborating with internal and external research groups to advance scientific understanding.
• Presenting research findings at international conferences and publishing in high-impact peer-reviewed journals.
• Managing laboratory operations, including equipment, supplies, and safety protocols.
• Staying abreast of the latest advancements and trends in molecular biology and related fields.
• Contributing to the strategic direction of the research department and identifying new areas of scientific inquiry.
• Ensuring rigorous data integrity and adherence to ethical research practices.

Qualifications:

• Ph.D. in Molecular Biology, Genetics, Biochemistry, or a related life science discipline.
• Minimum of 10 years of postdoctoral research experience with a strong publication record in leading scientific journals.
• Demonstrated expertise in a broad range of molecular biology techniques (e.g., PCR, qPCR, Western blotting, gene editing, next-generation sequencing, protein purification).
• Proven experience in leading and mentoring research teams.
• Successful track record of obtaining research grants from major funding agencies (e.g., NIH, NSF).
• Excellent analytical, critical thinking, and problem-solving skills.
• Exceptional written and verbal communication and presentation skills.
• Experience in data analysis and bioinformatics tools is highly desirable.
• Ability to foster a collaborative and innovative research environment.
• Strong understanding of research ethics and regulatory compliance.

This is a remarkable opportunity for an established scientist to make significant contributions to human health through innovative molecular research in a collaborative and supportive environment.

Our client, a leading research institution located in Portland, Oregon, US , is seeking a highly motivated and innovative Research Scientist specializing in Molecular Biology. This critical role will involve designing, executing, and analyzing complex experiments to advance our understanding of cellular mechanisms and disease pathways. The successful candidate will be responsible for developing novel research protocols, troubleshooting experimental procedures, and interpreting large datasets using advanced bioinformatic tools. You will collaborate closely with a multidisciplinary team of scientists, engineers, and clinicians to achieve project milestones and contribute to high-impact publications and grant applications. Key responsibilities include managing laboratory operations, ensuring compliance with safety regulations, and mentoring junior research staff. A Ph.D. in Molecular Biology, Genetics, Biochemistry, or a closely related field is mandatory. Postdoctoral experience with a strong publication record is highly preferred. Expertise in techniques such as PCR, qPCR, Western blotting, CRISPR-Cas9 gene editing, next-generation sequencing (NGS), and cell culture is essential. Familiarity with flow cytometry and microscopy is also valuable. The ideal candidate will possess exceptional problem-solving skills, a meticulous attention to detail, and the ability to work independently as well as collaboratively in a fast-paced research environment. Excellent written and oral communication skills are required for presenting findings at conferences and authoring manuscripts. This position offers state-of-the-art facilities and resources, competitive compensation, and opportunities for professional development and career advancement within a renowned research organization. The work is primarily lab-based, requiring hands-on experimental execution.

Our client, a leading innovator in biotechnology, is seeking a highly accomplished Principal Scientist specializing in Molecular Biology to join their Research & Development team. This senior role is instrumental in driving groundbreaking research and contributing to the discovery and development of novel therapeutic solutions. You will lead complex research projects, mentor junior scientists, and contribute to the scientific strategy of the department. Responsibilities include:

• Designing and executing complex molecular biology experiments to investigate biological pathways and targets.
• Developing and optimizing novel molecular assays and techniques.
• Analyzing and interpreting experimental data, drawing robust conclusions, and presenting findings at scientific meetings and conferences.
• Leading research projects from conception through to data generation and reporting.
• Mentoring and guiding junior scientists, fostering a collaborative and intellectually stimulating research environment.
• Collaborating with cross-functional teams, including computational biology, pharmacology, and clinical development.
• Contributing to the development of the company's scientific strategy and research pipeline.
• Writing and contributing to peer-reviewed publications and patent applications.
• Managing laboratory resources, including equipment and supplies.
• Staying current with the latest scientific literature, techniques, and advancements in molecular biology and related fields.
• Ensuring all research activities are conducted in compliance with ethical guidelines and safety protocols.

The ideal candidate will possess a Ph.D. in Molecular Biology, Biochemistry, or a related life science discipline, with a minimum of 8-10 years of post-doctoral research experience in an academic or industry setting. A strong publication record and experience in leading research projects are essential. Expertise in a range of molecular biology techniques such as PCR, qPCR, gene editing (CRISPR), next-generation sequencing (NGS), and mammalian cell culture is required. Experience with bioinformatics tools for data analysis is a plus. Excellent critical thinking, problem-solving, and communication skills are paramount. This position offers a hybrid work model, combining remote work flexibility with essential on-site laboratory presence at our facility in Nashville, Tennessee, US .