5 Peptide Chemistry jobs in the United States

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at no-style="text-align:left;">Job Function:

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Post Doc – Drug Discovery & Pre-Clinical/Clinical Development

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Career Program

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Spring House, Pennsylvania, United States of America

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at are searching for the best talent for a Postdoctoral Scholar, Peptide Chemistry to join the Global Discovery Chemistry team within the Therapeutics Discovery Organization in Springhouse, PA.

Purpose:

The focus of this position is to design and synthesize peptides to understand and improve permeability via passive and active transport. The successful candidate with be a highly motivated and technically skilled individual with a strong background in peptide chemistry. This postdoctoral position will last 24 months and offers an exciting opportunity to drive innovation in this emerging therapeutic modality.

You will be responsible for:

• Apply various chemical peptide modifications to understand factors influencing permeability of peptides to enhance oral bioavailability.
• Design and synthesis of peptides for active targeting approaches including conjugation to ligands
• Work directly with colleagues across GDC, TDS, and TPPIT to evaluate results and design optimized peptides
• Development, training, conferences, internal meetings & symposia

Required Knowledge, Skills and Abilities:

• A Ph.D. in peptide, synthetic organic, or medicinal chemistry. Degree must be completed within the past 3 years or to be completed within the upcoming 6 months.
• Strong background in peptide chemistry and characterization techniques
• Strong track record of achievement in the synthesis of complex molecules and/or synthetic methodology development, with deep knowledge of modern synthetic & analytical techniques
• Proven track record of scientific contributions including peer reviewed publications, patents and presentations
• Strong interpersonal skills and experience in collaborative, multidisciplinary team environments.
• Excellent oral and written communication skills

Preferred Knowledge, Skills and Abilities

• Experience with parallel peptide synthesis platforms
• Permeable and/or orally bioavailable peptides a plus
• Oral peptide design strategies including incorporation of unnatural amino acids
• Strong track record of scientific contributions including peer reviewed first-author

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ( ) or contact AskGS to be directed to your accommodation resource.

Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok ( .
Job Description
AbbVie Product Development Science & Technology (PDS&T) is seeking a Principal Research Scientist, Peptide Chemistry to conduct late-stage development and commercialization of Peptides, from registration through commercialization and the product lifecycle. We are seeking a highly motivated candidate with a proven track record of accomplishment in the field of peptide manufacturing development, to work in a multi-functional team environment at our North Chicago, IL location.
Key Responsibilities:
· The candidate will contribute to and/or lead cross-functional project teams associated with manufacturing process development, process characterization/justification, transfer of technology to manufacturing sites, and support manufacturing activities for peptides and potentially other modalities:
· Provide leadership in a matrixed team setting, while acting as an SME for peptide processes, interacting with various cross-functional groups and stakeholders and contributing to AbbVie's peptide manufacturing strategies.
· Set project strategies, define project responsibilities and timelines
· Author and review key regulatory documents, laboratory data, technical memos and reports.
· The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, and solid-state scientists.
· The position also entails interfacing with many groups external to PDS&T, for example: Manufacturing Operations, Regulatory Affairs, Quality Assurance, etc.
Responsibilities:
· Effectively functions as a principal investigator, generating original technical ideas and demonstrating creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals. Make significant contributions to project team through lab-based activities. Independently responsible for project science within his/her area of expertise on one or more project teams.
· Authors and/or reviews technical reports, manufacturing batch records and regulatory documents concerning Chemistry, Manufacturing and Control (CMC) subjects. Primary author of publications, presentations, and/or primary inventor of patents.
· Potential to mentor/supervise a team of one or more individuals, evaluate the performance of those individuals and be accountable for the effective performance of those individuals.
· Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.
Qualifications
· Bachelor's Degree or equivalent education and typically 14+ years of experience; master's degree or equivalent education and typically 12+ years of experience; PhD and typically 6+ years of experience in organic chemistry with a focus on peptide synthesis. Candidates with less experience may be considered for other opportunities.
· Experience in peptide process development and commercialization.
· A broad range of functional expertise in modern organic chemistry, mechanistic understanding, compound purification, control strategy development and standard analytical methodology (e.g., HPLC, UPLC, LC-MS, NMR).
· Demonstrated scientific communication and presentation skills. Experienced and demonstrated success as author of publications, presentations, and/or primary inventor of patents.
· Strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to lead cross-functional process development teams.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
+ The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. Salary: $121,000 - $30,000
+ We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
+ This job is eligible to participate in our short-term incentive programs.
+ This job is eligible to participate in our long-term incentive programs

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
$1 1,000 - 230,000

Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok ( .
Job Description
AbbVie's Synthetic Molecules Analytical Research & Development (Analytical R&D) is a global scientific organization responsible for all analytical CMC activities related to the development of AbbVie's pharmaceutical products.  Our scope includes AbbVie's diverse pipeline of innovative synthetic molecules and spans from the selection of Discovery candidate molecules through Early-Stage Clinical Development.  We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVie's pipeline of innovative medicines.  Careers in AbbVie Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.  We are looking for diverse candidates with strong scientific background and leadership experience to join the AbbVie's Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates. 
For the Principal Research Scientist position, we are seeking a highly motivated, experienced scientist, with expertise in peptide chemistry and associated analytical techniques. This will be supporting early phase development of synthetic peptides, including drug substance and drug product in both preclinical and clinical programs.  In addition, the candidate will have the opportunity to drive research initiatives related to peptide design and characterization.
The candidate should have experience in applying regulatory guidelines within an R&D environment with a fit for purpose mind set.  He/she should be able to perform research along with directing research by effectively mentoring, guiding and/or supervising scientific personnel. He/she must foster productive collaborations within the global Analytical R&D organization and with R&D cross-functional partners such as Pre-Clinical Safety, Process Chemistry, Process Engineering, Drug Product Development, Molecular Profiling and Drug Delivery, Quality Assurance and CMC-Regulatory.  
Key Responsibilities:
+ The candidate will participate and/or lead analytical teams associated with drug substance and drug product development and characterization of peptides and other emerging modalities.
+ Responsible for fit-for purpose method development, testing procedures, justifying specifications, and implementation of analytical control strategies to help the advancement of drug discovery candidates.
+ Proactively advise and share knowledge and expert opinions with subordinates, peers, and senior management.
+ Mentor and develop scientific staff in troubleshooting strategic and experimental issues and foster a culture of knowledge sharing.
+ Leverage prior experience to author and review key regulatory documents, laboratory data, technical memos and reports.
+ The position involves multi-disciplinary collaborations across Discovery, Development, Manufacturing, and Regulatory to execute and deliver material and information for clinical trials and regulatory submissions.
+ Generate new scientific proposals, related to peptides and other emerging modalities, and lead those efforts.
Qualifications
Minimum Qualifications:
+ Bachelors, Masters, or Ph.D. in Analytical Chemistry typically with a minimum of 14 (BS), 12 (MS), or 6 (Ph.D.) years related industry experience.
+ Experience with analytical aspects of advancing peptide modalities.
+ Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshoot analytical methods.
+ Hands on experience with UHPLC analysis and method development along with fundamental understanding and working knowledge of various analytical techniques including Dissolution, MS, GC, and NMR.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
+ The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
+ We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
+ This job is eligible to participate in our short-term incentive programs.
+ This job is eligible to participate in our long-term incentive programs

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
$121,000 - $230,000

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
An exciting opportunity is available for a highly skilled and experienced scientist with expertise in peptide process chemistry to join the Synthetic Molecule Design and Development (SMDD) division at Eli Lilly and Company! You will be part of a dynamic, cross-functional Department focused on sustainable synthetic peptide development and commercialization. In this role, you'll lead a variety of peptide commercialization projects, collaborate with external partners, and help advance next-generation, sustainable approaches to peptide manufacturing at the commercial scale.
We're looking for an innovative and energetic peptide chemist with a strong leadership background and deep industry knowledge. You'll work closely with a growing team of chemists, analysts, and engineers to design synthetic routes and optimize commercial peptide processes. Join us to help us deliver the next generation of therapies to patients around the world!
In this role you will work in a highly collaborative environment with key partners across the United States, Asia, and Europe, so a demonstrated record of collaborate effectively and communicate clearly is essential.
**Top candidates for this position will:**
+ Demonstrate excellence in multiple modes of peptide synthesis including hybrid SPPS/ LPPS peptide chemistry.
+ Have experience leading a team of scientists developing peptide synthesis routes.
+ Enable the design, development, and implementation of sustainable, innovative processes for the synthesis of complex peptides.
+ Implement green chemistry and engineering solutions as a means of improving the environmental footprint in the synthetic peptide field: Lowering Process Mass Intensity in Peptide Synthesis ( Have familiarity with chromatography, mass spectrometry, optical spectroscopy, and peptide automation.
+ Have strong technical problem-solving ability and have an internal motivation to succeed in team environments.
+ Have a track record of innovative scientific research, as demonstrated by publication in high quality, peer reviewed journals and presentations at external conferences.
**Position Responsibilities:**
+ Lead a team of peptide chemists in designing sustainable synthetic peptide processes.
+ Provide oversight for development of multi-kg synthetic peptide processes at contract manufacturing organizations for peptide products.
+ Educate contract manufacturing organizations in best practices for greener peptide development and manufacture.
+ Engage with Eli Lilly's Development and Manufacturing organizations to develop a deep understanding of new initiatives and improve existing scientific processes.
+ Present research findings at internal forms as well as external conferences and publish in high quality, peer-reviewed journals. Strong written and verbal communication to speak to both technical and business-related implications of your work.
+ Familiarity with Tag Assisted Liquid Phase Peptide Chemistry.
**Basic Qualifications:**
+ PhD in Chemistry or related field with 7 + years of pharmaceutical industry experience or 12 + years' experience in related industries or academics.
**Additional Skills/Preferences:**
+ Good interpersonal skills and a sustained tendency for collaboration.
+ Ability to learn and apply technical knowledge to meet changing project needs.
+ Flexibility and ability to prioritize work to meet interpersonal and scientific goals.
+ Demonstrated leadership capabilities especially in a team environment.
+ Ability to balance multiple activities, prioritize and handle ambiguity.
**Additional Information** :
+ Travel: 0 to 10%
+ Position Location: Indianapolis, IN; Lilly Technology Center-North (LTC-N)
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$144,000 - $250,800
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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