575 Software Engineer jobs in San Francisco

Who we are  

At PrognomiQ, we aim to develop and commercialize transformative tests for early detection and treatment of cancer and other complex diseases. To accomplish this, we are leveraging leading proteomics technology, including the Proteograph product suite from Seer Bio, in combination with other multi-omics assays to develop unprecedented molecular views of health and disease. We are a team of experienced and accomplished scientists supported by a group of leading investors in healthcare and technology.  

Would you like to be at the leading edge of molecular data generation and analyses that changes how cancer and other complex diseases are detected and treated? Or are you looking to bring innovative and disruptive solutions to market? If you answer “yes” to either of these questions, let us know by applying!  

Description of role   

We are seeking a highly skilled Software Engineer to lead the development and scaling of our cloud-based backend systems and Laboratory Information Management Systems (LIMS). The ideal candidate will play a critical role in driving the architecture, implementation, and deployment of core services supporting our diagnostics platform. 

This is an on-site or hybrid work position with expectations of being on-site a few times a week.

Duties:  

• Communicate with the third-party vendor to develop and customize the LIMS system for products. 
• Lead the design and development of backend services and APIs that power core product features. 
• Work within cloud infrastructure environments, e.g., Amazon Web Services (AWS), and implement Infrastructure as Code using tools like Terraform. 
• Make high-impact architectural decisions across backend systems with an emphasis on performance, scalability, and security. 
• Drive engineering best practices, code quality, and architecture patterns across the team. 
• Collaborate with cross-functional teams to streamline laboratory workflows through software automation. 

Requirements:  

• B.S., M.S., or Ph.D. in Computer Science related technical field, or equivalent practical experience
• 5+ years of experience in the related field 
• Strong programming skills in languages like Python, C++, JavaScript 
• Proven experience designing and building scalable backend systems and APIs. 
• Proven experience with cloud platforms (e.g., AWS, GCP, or Azure). 
• Strong proficiency in web framework (e.g., Django, Flask etc.) and architectural design. 
• Experience configuring and customizing LIMS platforms to support operational needs in lab settings. 
• Proficiency with Infrastructure as Code (e.g., Terraform). 
• Strong problem-solving skills and ability to work independently and collaboratively. 

Preferred: 

• Understanding of regulatory and compliance frameworks such as CLIA, HIPAA, and 21 CFR Part 11. 
• Experience working in a clinical, diagnostics, or biotech environment. 
• Experience in LIMS integration and system integration for clinical applications or products 
• Experience with continuous integration and deployment systems and tooling
• Experience with containerization and orchestration tools like Docker 
• Experience developing and maintaining codebases and software libraries following industry best practices

  Note:

• Salary range varies based on demonstrated experience.

Equal Opportunity Employment  

PrognomiQ is an equal opportunity employer that celebrates diversity and inclusion in the workplace. We prohibit discrimination and harassment of any kind based on race, color, sex, religion, sexual orientation, national origin, disability, genetic information, pregnancy, or any other characteristic protected by law. This policy applies to all employment practices within our organization, including hiring, recruiting, promotion, termination, layoff, recall, leave of absence, compensation, benefits, training, and apprenticeship. 

Zams is an AI command center for B2B sales teams. It connects to the tools you already use—Salesforce, Hubspot, Slack, Apollo, Gong and more—and turns them into one seamless system. Instead of clicking through tools, you just say what you want in English and Zams does it.

We’re a small, scrappy team backed by some of the top venture capital firms in the US, moving fast with a strong bias for action and attention to detail. Joining Zams now means stepping onto the ground floor of a company with a massive mission and momentum. You’ll have the chance to make an outsized impact, see your ideas go from concept to reality in weeks, and play a direct role in shaping how companies everywhere adopt AI. It’s the perfect environment for someone who thrives in fast-paced startups, wants to learn quickly, and is ready to grow alongside a team that’s defining the future of sales.

As a Software Engineer at Zams, you'll be on the ground floor of an incredible opportunity to pair your engineering mastery with solving critical business challenges across industries. Zams is already powering automation for companies, and our users deeply value our speed, reliability, and customer-centric approach.

In this role, you’ll be a core contributor to the product itself—not just building features, but shaping the way the entire platform evolves. You’ll work across all layers of the stack, from crafting intuitive frontends to architecting robust backend systems. This is a rare opportunity to touch every component of a high-impact product, while working side by side with the founding team.

We're looking for someone who thrives in a scrappy, fast-paced environment, has strong knowledge of AI and LLMs, and is eager to learn continuously. You should be excited by the idea of solving a wide range of engineering and data challenges with autonomy and ownership. If you’re passionate about building, shipping fast, and learning new things every day, we’d love to meet you.

• Be a key engineer driving the development of Zams’ core product, helping ship meaningful features rapidly and iteratively.
• Work end-to-end across the stack, including backend services, frontend interfaces, infrastructure, and developer tools.
• Handle critical aspects of frontend development, including routing, state management, authentication guards, and UI frameworks like Tailwind and ShadCN.
• Design, build, and scale reliable SaaS applications with a focus on performance and usability.
• Deploy and manage apps via Vercel or similar platforms.
• Leverage AI-powered developer tools such as Cursor or other coding copilots to accelerate engineering workflows.
• Collaborate closely with the founders and a small, agile team in an in-office environment, contributing to both customer-facing products and internal innovation projects.
• Continuously explore and integrate new tools, patterns, and frameworks to improve engineering velocity.

Requirements

• 1+ years of experience as a Full Stack Developer (or similar role) in a professional environment
• Strong knowledge and experience with AI and LLMs
• Experience with Next.js and Node.js
• Strong with Typescript
• Proficiency in React.js, including libraries, state management, routing, and authentication guards.
• A history of working on multiple SaaS applications, either end-to-end or on key components.
• Demonstrated ability to work independently or in small teams, ideally in startup environments.
• Strong portfolio of personal passion projects, hackathon participation, or side projects.
• Entrepreneurial mindset—has either worked at a startup or attempted to start one.
• Highly motivated and in the early stages of their career (20s), eager to prove themselves and be part of something big.
• Strong ability to identify what makes a product “good” from both a technical and user perspective.

Benefits

• Equity Package
• Unlimited PTO
• Training & Development

A Day in the Life:

Come join us in our effort to digitally transform Hertz! Recent innovations such as smartphones, electric vehicles, and ride-hailing apps have created new and exciting opportunities in transportation that Hertz is uniquely positioned to capitalize on. We're looking for software engineers who will modernize Hertz's tech stack and, in the process, ship delightful products to meet the ever-increasing demands of our customers.

What you will do:

• Design, implement and maintain applications that can be high-volume and low-latency

• Contribute to all stages of software development lifecycle

• Analyze user requirements to define business objectives

• Envisioning system features and functionality

• Develop and test software

• Identify and resolve any technical issues arising

• Create detailed design documentation

• Propose changes to current infrastructure

• Develop technical designs for application development

• Write well designed, testable code

• Conducting software analysis, programming, testing, and debugging

• Support continuous improvement, investigating alternatives and technologies, and presenting for architectural review

What We're Looking For:

• 0-2 years of experience in the technology industry, and a B.S. in Computer Science or equivalent

• Proficiency in one or more programming languages and common data structures / algorithms

• Ability to write production-ready code with moderate supervision

• Ability to design systems of moderate complexity

• Ability to conduct code reviews and give sign-off for code merges

• Strong communication skills. You must be able to work with cross-functional partners to gather requirements and explain outcomes

• Strong product sense. You must be able to align your work with business objectives and make appropriate tradeoffs

• Learning mentality. You must be able to pick up new skills as needed and demonstrate a curiosity about new technologies

We expect the starting salary to be around $100,000 to $125,000 with annual bonus and profit sharing eligibility. The actual salary will be determined based on years of relevant work experience

What You'll Get:

• Up to 40% off any standard Hertz Rental?

• Paid Time Off

• Medical, Dental & Vision plan options

• Retirement programs, including 401(k) employer matching

• Paid Parental Leave & Adoption Assistance

• Employee Assistance Program for employees & family

• Educational Reimbursement & Discounts

• Voluntary Insurance Programs - Pet, Legal/Identity Theft, Critical Illness

• Perks & Discounts -Theme Park Tickets, Gym Discounts & more

The Hertz Corporation operates the Hertz, Dollar Car Rental, Thrifty Car Rental brands in approximately 9,700 corporate and franchisee locations throughout North America, Europe, The Caribbean, Latin America, Africa, the Middle East, Asia, Australia and New Zealand. The Hertz Corporation is one of the largest worldwide airport general use vehicle rental companies, and the Hertz brand is one of the most recognized in the world.

US EEO STATEMENT

At Hertz, we champion and celebrate a culture of diversity and inclusion. We take affirmative steps to promote employment and advancement opportunities. The endless variety of perspectives, experiences, skills and talents that our employees invest in their work every day represent a significant part of our culture - and our success and reputation as a company.

Individuals are encouraged to apply for positions because of the characteristics that make them unique.

EOE, including disability/veteran

The Skywalker Sound Development Group is looking for a Software Engineer to join our team.

The Skysound Development Group is developing the set of next-generation tools for audio soundtracks and media distribution. We aim, through the synthesis of institutional wisdom of creative, high quality audio with cutting-edge software engineering, to bridge the divide between content creation and audience experience.

As a Software Engineer within the Group, you will play a key role in conceiving and developing tools to help usher in the new era of post production audio content creation, working in areas such as application development, cloud computing, database, and state-of-the-art security implementation. The Development Group works closely with master audio content creators to produce novel technology for immediate utilization.

This role is considered Hybrid, which means the employee will work 2-3 days onsite at our Nicasio office and occasionally from home.

What you'll do

• Design and implement media pipeline components and modules

• Iterate and prototype new features during project evolution

• Implement and maintain secure code practices, utilizing security and scanning toolsets

• Address and develop multiple project components in parallel

• Research and incorporate state-of-the-art approaches to recognized challenges

• Proactively identify and address areas for improved efficiency and product quality

• Collaborate with team members in shared libraries, techniques and code responsibilities

What we're looking for

• Bachelor's degree in Computer Science, Engineering, or a related field, or equivalent professional experience.

• 4+ years of prior experience with media-based software workflows

• Proficiency with Go, JavaScript/TypeScript, and Python

• Some familiarity with C/C++ and low-level toolchains such as Makefile

• Well-rounded experience in front-end and back-end development

• Strong implementer of defensive coding techniques to mitigate security risks

• Strong object-oriented programming experience with test-driven development

• Vast experience in database design and implementation including relational and in-memory databases

• Familiarity with open-source and cloud-based message brokers and serverless

• Experience with container-based development and deployments

• Strong foundational knowledge of API architectures including REST and gRPC

• Fundamental understanding of Git, Kubernetes, and continuous integration

• Strong understanding of media-based workflows and media metadata

• Must be detail oriented and organized, possess strong communication skills, and be able to handle a variety of tasks in an efficient manner.

Preferred experience

• Developed front-end interfaces with React or similar technologies

• Experience with cross-platform software projects

• Strong information system security knowledge

The hiring range for this position in San Francisco, CA is $128,700 to $172,500 per year. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. A bonus and/or long-term incentive units may be provided as part of the compensation package, in addition to the full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Job ID:

Location: Nicasio,California

Job Posting Company: Lucasfilm

The Walt Disney Company and its Affiliated Companies are Equal Employment Opportunity employers and welcome all job seekers including individuals with disabilities and veterans with disabilities. If you have a disability and believe you need a reasonable accommodation in order to search for a job opening or apply for a position, email with your request. This email address is not for general employment inquiries or correspondence. We will only respond to those requests that are related to the accessibility of the online application system due to a disability.

Description

If you are interested in this position, please apply on Twitch's Career site

About Us:

Twitch is the world's biggest live streaming service, with global communities built around gaming, entertainment, music, sports, cooking, and more. It is where thousands of communities come together for whatever, every day.

We're about community, inside and out. You'll find coworkers who are eager to team up, collaborate, and smash (or elegantly solve) problems together. We're on a quest to empower live communities, so if this sounds good to you, see what we're up to on LinkedIn and X, and discover the projects we're solving on our Blog. Be sure to explore our Interviewing Guide to learn how to ace our interview process.

About the Role

As a Software Engineer on the On Demand Products team, you'll build and maintain the interactive experiences that millions of creators and viewers use daily on Twitch. Working closely with experienced engineers, you'll develop your full stack capabilities while focusing on creating responsive, performant products.

You can work from San Francisco, CA; Seattle, WA; or New York City, NY!

You Will

• Build and maintain scalable frontend features using TypeScript and React that power Twitch's VOD and Clips features.

• Collaborate with the team to design and implement Twirp APIs and backend services in Golang

• Drive frontend best practices including accessibility, performance, and testing methodologies

• Work closely with Product, Design, and other engineering teams to deliver exceptional user experiences

Perks

• Medical, Dental, Vision & Disability Insurance

• 401(k)

• Maternity & Parental Leave

• Flexible PTO

• Amazon Employee Discount

Basic Qualifications

• Bachelor's degree in Computer Science or related field, or equivalent industry experience

• Demonstrated ability to write clean, well-tested, and maintainable code

• Understanding of web fundamentals including HTML5, CSS3, and RESTful APIs

• Experience with software development fundamentals, data structures, and algorithms

Preferred Qualifications

• Strong foundation in modern JavaScript/TypeScript development and React ecosystems

• Experience with large-scale frontend applications and state management

• Experience with large-scale frontend applications and state management

• Knowledge of AWS services and cloud infrastructure

Twitch is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.

Los Angeles County applicants: Job duties for this position include: work safely and cooperatively with other employees, supervisors, and staff; adhere to standards of excellence despite stressful conditions; communicate effectively and respectfully with employees, supervisors, and staff to ensure exceptional customer service; and follow all federal, state, and local laws and Company policies. Criminal history may have a direct, adverse, and negative relationship with some of the material job duties of this position. These include the duties and responsibilities listed above, as well as the abilities to adhere to company policies, exercise sound judgment, effectively manage stress and work safely and respectfully with others, exhibit trustworthiness and professionalism, and safeguard business operations and the Company's reputation. Pursuant to the Los Angeles County Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit for more information. If the country/region you're applying in isn't listed, please contact your Recruiting Partner.

Our compensation reflects the cost of labor across several US geographic markets. The base pay for this position ranges from $99,500/year in our lowest geographic market up to $200,000/year in our highest geographic market. Pay is based on a number of factors including market location and may vary depending on job-related knowledge, skills, and experience. Amazon is a total compensation company. Dependent on the position offered, equity, sign-on payments, and other forms of compensation may be provided as part of a total compensation package, in addition to a full range of medical, financial, and/or other benefits. For more information, please visit . This position will remain posted until filled. Applicants should apply via our internal or external career site.

We are Rokt, a hyper-growth ecommerce leader. Rokt is the global leader in ecommerce, unlocking real-time relevance in the moment that matters most. Rokt’s AI Brain and ecommerce Network powers billions of transactions connecting hundreds of millions of customers, and is trusted to do this by the world’s leading companies.

We are a team of builders helping smart businesses find innovative ways to meet customer needs and generate incremental revenue. Leading companies drive 10-50% of additional revenue—and often all their profits—from the extra products or services they sell. This economic edge unleashes a world of possibilities for growth and innovation.

At Rokt, we practice transparency in career paths and compensation. At Rokt, we believe in transparency, which is why we have a well-defined career ladder with transparent compensation and clear career paths based on competency and ability. Rokt’stars constantly strive to raise the bar, pushing the envelope of what is possible.

A fixed annual salary of $100,000 - $170,000, an employee equity plan grant, and world-class benefits. 

Equity grants are issued in good faith, subject to company policies, board approval, and individual eligibility.

About the role: 

Join Rokt as a Software Engineer and become a driving force in building AI-powered products that shape the future of ecommerce. In this high-impact role, you’ll leverage cutting-edge AI tools and a builder’s mindset to develop scalable solutions used by millions of customers worldwide. If you’re excited by the challenge of turning bold ideas into reality and pushing the boundaries of what’s possible with AI, this opportunity is for you.

Requirements

• Design & Build Innovative Products : Develop and iterate on next-generation ecommerce features and services, using AI and machine learning to create intelligent, personalized experiences.
• Accelerate Development with AI: Leverage AI-driven tools and automation to speed up coding, testing, and deployment, allowing you to focus on creative problem-solving and quality.
• Full-Stack Product Ownership: Work across the entire product lifecycle—from ideation and prototyping to implementation and continuous improvement—ensuring each feature delivers real value.
• Collaborate & Innovate: Partner with product managers, designers, and other engineers to conceptualize and implement AI-driven solutions that enhance user experience and drive business outcomes.
• Optimize & Scale : Identify performance bottlenecks and opportunities for improvement in our systems. Use data insights to refine user interfaces, optimize algorithms, and ensure our platform can scale to billions of transactions.
• Drive Revenue Growth: Spearhead the development and deployment of innovative features and capabilities that directly drive growth of the business, with the potential to generate millions of dollars in additional revenue.

• AI-Enthusiast & Quick Learner: You embrace new technologies (like AI/ML frameworks) and learn rapidly, adapting to innovative tools and workflows to stay ahead of the curve.
• Problem Solver: You excel at breaking down complex problems using first principles and creativity. Challenges are puzzles you’re excited to solve.
• Entrepreneurial Mindset: You take ownership of outcomes, move fast with confidence, and aren’t afraid to navigate ambiguity—figuring things out independently when needed.
• Collaborative Team Player: You communicate clearly and work well with cross-functional teams. You value feedback, share ideas openly, and help others succeed.
• Driven & Results-Oriented: You set high standards for your work, take pride in delivering quality, and continually seek to improve. You care about the impact of your code on the business and customers.

Benefits

• Build the Future of AI in Ecommerce: Be at the forefront of AI-driven transformation in a company that’s pioneering how brands engage customers in the “moment that matters” during online transactions.
• Hyper-Growth = Fast Progression: Rokt is a rapidly growing tech leader, which means huge opportunities for your career advancement, learning, and taking on bigger responsibilities quickly.
• Culture of Builders: Work with a smart, humble, and bold team that shares a “builder” DNA – we love to innovate, take risks, and turn ambitious ideas into tangible results. We win as a team and learn from every experiment.
• Ownership & Impact: Every Rokt’star (employee) has a voice and real equity in the company. You’ll have autonomy to make decisions, drive projects, and see the direct impact of your work on millions of users.
• World-Class Benefits & Support: Join a people-first culture with transparent career paths, continuous development, and great perks (equity grants, catered lunches, global offices, and more) that empower you to do your best work.

About The Benefits:

We leverage best-in-class technology and market-leading innovation in AI and ML, with all of that being underlined by building and maintaining a fantastic and inclusive culture where people can be their authentic selves, and offering a great list of perks and benefits to go with it:

• Become a shareholder. Every Rokt’star gets equity in the company
• Enjoy catered lunch every day and healthy snacks in the office. Plus join the gym on us! 
• Extra leave (bonus annual leave, sabbatical leave etc.) 
• Access generous retirement plans like a 4% dollar-for-dollar 401K matching plan and get fully funded premium health insurance!
• Dog-friendly office
• Work with the greatest talent in town
• See the world! We have offices in New York, Seattle, Sydney, Tokyo and London

We believe we’re better together. We love spending time together and are in the office most days (teams are in the office 4 days per week).

We at Rokt choose to create a company that is as diverse and inclusive as the world we live in by attracting, growing & keeping the best talent. Equal employment opportunities are available to all applicants without regard to race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

If this sounds like a role you’d enjoy, apply here, and you’ll hear from our recruiting team.

Note: The first stage of the recruitment process for this role is to complete a 15-minute online aptitude test as well as an employee personality profile assessment, which will be sent out to your application email. Successful candidates will be contacted to discuss the next steps.

About General Medicine

As a software engineer at General Medicine, you’ll help build and scale a healthcare store that makes it delightfully simple to shop for any type of care. We provide upfront cash and insurance prices for virtual and in-person visits, prescriptions, labs, imaging, and more.

What we’re looking for

We’re looking for strong engineers to help us build a seamless and beautiful consumer healthcare product. We’re looking for folks who will obsess over every detail of our patient experience, and also tackle the complex operational challenges of delivering care at scale. We are looking for engineers who care deeply about technical excellence but are also comfortable moving quickly — we are constantly navigating tradeoffs between engineering velocity and quality.

Our ideal candidate is hungry, high-agency, and aspires to be a generalist. Our engineers frequently write product requirements documents, write SQL to understand how features are performing, and own QA — no task is beneath us or outside of the scope of the role if it helps us to deliver a great product. We're looking for someone who can operate in an environment of significant ambiguity, and who is comfortable working closely with design, operations, and clinical stakeholders.

We don’t expect you to have a healthcare background (though it’s great if you do!). However, you should be excited by the prospect of digging into the messy complexities of the American healthcare system (integrating with EHRs, revenue cycle management, etc).

Qualifications

• 2+ years of experience building web apps as a full-stack engineer
• Experience with modern infra tooling and programming languages. We currently use AWS, Ruby on Rails, and NextJS, and would expect you to have proficiency in a modern tech stack even if it isn’t the one we are using.

Please note that this role would be based in SF, and that we expect our team to be in the office at least 3 days/week.

Why join us

We’re an experienced team that has built a company in this space before, our product has clear product-market fit, and we’ve raised money from top investors.

We have an ambitious and distinctive vision for what can be built in consumer healthcare. We believe LLMs and price transparency legislation have opened up several massive opportunities.

If you’re an ambitious and entrepreneurial software engineer and this resonates, please apply.