214 Researchers jobs in Boston

Research & development at Vaxess is cross-disciplinary, integrating basic science and engineering to transform delivery of next-generation therapies and vaccines. We are seeking a talented, collaborative, and highly motivated individual with expertise in translational animal models and wet lab techniques to join our core team of preclinical scientists and engineers. This is a unique opportunity to be part of an emerging early phase clinical company bringing innovative microneedle therapeutic delivery technology to the global market.

Responsibilities

• Support in vivo studies, including PK and safety studies in rat and swine. This includes preclinical animal model development and IND-enabling safety and efficacy studies across pipeline programs.
• Track ongoing animal studies, coordinating tasks from vivarium organization and test article administration to tissue harvest and downstream processing
• Characterize microneedle array patch (MAP) test articles deployed into preclinical models, e.g. by visual inspection, skin penetration, dose delivery and potentially other performance measurements
• Perform initial biometric tests on animals and downstream blood and tissue harvests to support bioassays that assess treatment effects
• Contribute to study design and protocol and report writing; communicate logistical needs and present work in team meetings
• Collaborate closely with scientists and engineers to advance drug candidates from research through Phase I/II clinical trials
• Maintain accurate laboratory records and electronic lab notebook entries
• Travel to testing facilities in the greater Boston area, potentially several times per week; transport test articles and equipment as needed.

Qualifications

• Bachelors degree in one of the Life Sciences with at least 2 years of related work experience OR Masters degree in one of the Life Sciences with 0-2+ years of related work experience
• Hands-on experience with small rodent models, such as rats and mice, is required
• Familiarity with basic wet lab techniques, such as micropipetting, is required
• Experience with large animal technical procedures is considered a plus
• Strong organizational skills and attention to detail
• Excellent verbal and written communication skills
• Committed to working collaboratively with an interdisciplinary team

Vaxess, a venture-backed clinical-stage life sciences company, is building a team of exceptional people to rapidly advance products on its microneedle array patch (MAP) platform. We work closely as a team and thrive in a dynamic, exciting, and engaging work environment. We aim to recruit, employ, train, compensate and promote regardless of race, religion, color, national origin, sex, gender identity or expression, sexual orientation, disability, age, or veteran status. If youre interested in joining the Vaxess team, please submit your CV/resume to .

Job Listing Summary

Location: Boston, United States

Employment Type: Full-Time

Date Posted: July 31, 2025

Application Deadline: August 29, 2025

The Quantitative Research Associate Program at MFS is designed to immerse associates in the investment management business, supporting quantitative research, portfolio management, and investment risk management teams. Associates will work on stock selection models, proprietary software, and risk management processes, engaging with the broader investment team to meet analytical needs.

• Work within the quantitative research team on projects related to the development of quantitative alpha models.
• Assist in the development and implementation of disciplined quantitative investment processes focused on alpha generation, portfolio construction, and risk management.
• Address data and analytical requests from the investment department through active engagement and outreach.
• Effectively communicate results of processes and research within and outside of the quantitative group.
• Assume additional projects and responsibilities as required.

• Bachelor's degree in a relevant field (e.g., Finance, Economics, Mathematics, Engineering, or other quantitatively oriented discipline).
• Proficiency in analytical languages such as R, Python, Matlab.
• Proficiency in one or more of Java, C#, and SQL preferred.
• Familiarity with financial data software such as Bloomberg or FactSet is a plus.
• Exceptional analytical and problem-solving skills.
• Strong communication skills; both written and verbal.
• Attention to detail and commitment to accuracy.

MFS promotes a diverse and inclusive workplace and encourages applicants with varied experiences to apply. The position is not eligible for sponsorship, and applicants must be authorized to work in the United States on a full-time basis.

Join to apply for the Clinical Research Associate role at X4 Pharmaceuticals

Join to apply for the Clinical Research Associate role at X4 Pharmaceuticals

Reporting to: Senior Director, Clinical Operations

Do you have the passion and commitment to join a group whose mission is to develop treatments that have a clear and profound impact on patients suffering from rare diseases? Does it excite you to be a part of a patient-focused company developing potential new treatments that could dramatically improve the lives of patients with limited to no current treatment options? If yes, we encourage you to share with us your aspirations and career goals.

X4 is focused on restoring healthy immune system function by developing novel therapeutics to treat chronic neutropenic disorders, including WHIM syndrome, a rare primary immunodeficiency. We are advancing a novel, late-stage clinical candidate, mavorixafor, that we believe has the potential to become a new standard of care for patients with these disorders. We know that developing innovative, new medicines is challenging, and we invite new colleagues who share our values and commitment to join us in achieving our mission.

This opportunity will

• Align with your values and grit, and passion for innovative science.
• Leverage your knowledge of Clinical Operations to support our innovative science and allow you to have a major impact on our mission to support our patients.
• Offer a collegial environment with a team-based approach, where our mission drives our values, behaviors, and creativity.
  
  

• Collaborate with clinical trial sites and third-party vendors to ensure adherence to protocol(s) and study requirements; may include monitoring and co-monitoring responsibilities.
• Review documents for completeness, accuracy, and compliance with protocol and appropriate regulations; Identify issues and take appropriate corrective actions.
• Support sites in strategy for identification and screening of potential study participants, maintenance of appropriate documents for conduct of study at the site, and follow through on issues.
• Contribute to the creation and review of study-specific plans, specification documents, materials, and tools.
• Assist in preparing study-related documents (i.e., ICF, clinical trial tools, templates, training materials, manuals, study newsletters, etc.).
• Deliver and execute operational tasks, and assist in tracking study metrics, maintenance, and distribution of study trackers.
• QC oversight of CRO, TMF, Monitoring Visit Reports, Payments, Safety Alert acknowledgments, ICFs, and timelines.
  
  

• Bachelors degree required.
• Minimum of 2-5 years of experience in the biotech or pharmaceutical industry, with at least 2+ years direct experience as a Clinical Research Associate/Monitor.
• Working knowledge of ICH GCP regulations and clinical protocols.
• Demonstrated effectiveness in resolving complex site management issues.
• Requires exceptional attention to detail in composing and proofing materials, establishing priorities, scheduling, and meeting deadlines.
• Sound analytical and problem-solving skills; ability to act with a sense of urgency.
• Ability to work in a fast-paced environment with demonstrated agility to juggle multiple competing tasks and demands.
• Excellent written and verbal communication skills.
• Team player that takes initiative and is willing to support optimizing the way we work.
• This position requires up to 50% travel.
  
  

• Seniority level Mid-Senior level

• Employment type Full-time

• Job function Research, Analyst, and Information Technology

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Boston, MA $83,200.00-$124,800.00 2 weeks ago

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The Clinical Research Associate is responsible for supporting clinical activities for domestic and international studies as well as support other related initiatives, as required. Responsibilities Collaborate with team members in the evaluation and e Research, Associate, Manufacturing, Technology, Education, Travel, Support

Activ Surgical is seeking a highly motivated and detail-oriented Clinical Research Associate (CRA) to support the planning, execution, and monitoring of clinical studies for our advanced surgical visualization technologies. The CRA will play a critical role in pre-clinical trials, first-in-human trials, Phase I and Phase II studies, and ongoing clinical investigations across domestic and international sites. This position requires strong knowledge of FDA guidelines, Good Clinical Practice (GCP), and International Council for Harmonisation (ICH) regulations, with a proven ability to operate in fast-paced environments involving novel technologies.Key ResponsibilitiesClinical Trial Management Support planning, initiation, execution, and close-out of pre-clinical, first-in-human, Phase I, and Phase II clinical trials. Coordinate domestic and international trial activities, ensuring compliance with protocol, SOPs, GCP, ICH, and local regulatory requirements. Serve as primary liaison with clinical sites, investigators, and study staff. Ensure accurate collection, verification, and reporting of clinical trial data. Site Monitoring & Compliance Conduct site selection, qualification, initiation, routine monitoring, and close-out visits. Monitor adherence to study protocols, regulatory requirements, and patient safety standards. Identify, document, and resolve protocol deviations, ensuring corrective actions are implemented. Maintain up-to-date Trial Master File (TMF) and essential study documentation. Regulatory & Quality Oversight Ensure clinical trials are executed under FDA regulations, ISO standards, ICH/GCP guidelines, and Activ Surgical's quality system. Contribute to regulatory submissions, safety reporting, and preparation for FDA, EMA, or other agency audits/inspections. Assist with preparation of Investigator's Brochure, Clinical Study Reports, publications and presentations. Cross-Functional Collaboration Partner with R&D, Regulatory, Quality, and Commercial teams to align trial execution with corporate strategy. Provide clinical input to the development of novel surgical visualization technologies including Laser Speckle Contrast Imaging (LSCI), Multispectral Imaging (MSI), and AI-based applications. Support KOL engagement and training activities related to clinical trials. Qualifications Bachelor's or Master's degree in Life Sciences, Nursing, Biomedical Engineering, or related field. 2-5+ years CRA experience in medical device or biotech clinical trials; surgical device or imaging experience preferred. Demonstrated expertise in first-in-human studies, Phase I and II trials, and novel technology evaluation. Strong working knowledge of FDA, ICH, GCP, ISO 14155, and global regulatory frameworks. Experience with domestic and international site management and multi-country trial coordination. Excellent communication, organizational, and problem-solving skills. Proficiency in electronic data capture systems and common office software. Willingness to travel (15-25% domestic and international). Personal Attributes:•Teamwork-oriented with the ability to collaborate across functions and geographies•Operates with a sense of urgency in fast-paced, high-growth environments•Demonstrated adaptability, thriving in dynamic and evolving business models•Deeply customer- and patient-focused, ensuring solutions create measurable clinical and economic value•Skilled at balancing priorities in the order of CompanyTeamSelf to drive aligned outcomesRequirementsSupport med tech validations studies, ensuring imaging or device integration endpoints are properly captured Experience monitoring device trials, imaging / visualization platforms, or AI enabled systems strongly preferred. Benefits Health Care Plan (Medical, Dental & Vision) Retirement Plan (401k, IRA) Life Insurance (Basic, Voluntary & AD&D) Paid Time Off (Vacation, Sick & Public Holidays) Family Leave (Maternity, Paternity) Short Term & Long Term Disability Training & Development Work From Home Wellness Resources

Are you being referred to one of our roles by a connection in Alira Health? If so, please apply using the referral link emailed to you.Join our global team dedicated to innovation and initiative, where physical walls and different time zones don't limit, but encourage, collaboration. Where all contributions and new ideas are explored with an open mind and work is driven by our shared values: be courageous, be accountable, be honest, be inclusive and elevate others.Job Description SummaryAlira Health is looking for a Clinical Research Associate to join our team. Candidates should have 2+ years monitoring experience, including oncology.Job DescriptionROLEThe CRA is an important member of the Alira Health Clinical team. The CRA is highly motivated and functions independently to conduct site monitoring responsibilities for clinical trials; as well as providing oversight, leadership, and guidance in the management and execution of clinical trials to ensure compliance and quality. The CRA works closely with Lead CRAs, Sr CRAs, in-house CRAs, Director of Clinical Monitoring and Project Managers to ensure protocol compliance, address site questions, and assist with study recruitment, site training, and other site-related issues. KEY RESPONSABILITIESProvides guidance, oversight, and feedback to the CRA team to ensure adherence to project scope, SOPs, timelines, and budget requirements.Reviews monitoring visit reports, conducts co-monitoring and evaluation visits as needed.Ensures appropriate and timely investigator site visits.Coordinates with appropriate cross-functional departments to facilitate negotiation/issue resolution for clinical trial monitoring related issues.Assists in development of study-specific Monitoring Plans and training presentations as required.Assists in set up/collection of site specific ethics documents and site contract negotiation as required.Provides monthly billing information to finance team as required.For monitoring stand-alone projects, manages study budget and acts as referent for the sponsor.Performs qualification, initiation, interim, and close-out visits both remotely and onsite, ensuring proper documentation of monitoring visits.Prepares consistently accurate and timely monitoring visit reports documenting site-related problems, resolutions, actions taken, protocol deviations, study progress, and enrollment status.Ensures integrity of CRF data through meticulous and thorough source document review and verification.Performs quality control and verification of documents collected at sites for eTMF/TMF.Conducts investigational product accountability.Reviews site regulatory binder for required documents.Maintains regular contact with study sites to ensure protocol/GCP compliance, assesses patient accrual rates, and responds to sponsor requests.Complies with and ensures team compliance with ICH GCP guidelines, FDA regulations, and company/Sponsor SOPs.Participates in internal, client/sponsor, scientific, and other meetings as required.Facilitates adverse event reporting and ensures the reconciliation of SAE reports with source documentation and CRFs.Works closely with in-house CRAs/CTC and data management to resolve queries on discrepant data.Proactively identifies site issues and develops problem-solving strategies for sites.Conducts audit preparation at study sites as needed.Works with other CRAs to maintain consistency and promote a collaborative team atmosphere.Participates in internal, client/sponsor, scientific, and other meetings as required.Performs CRA mentoring.Collaborates with development and maintenance of Clinical Trial Management System (CTMS).Manages and resolves conflicting priorities to deliver on commitments.Performs additional duties as assigned.DESIRED QUALIFICATION & EXPERIENCEBachelor's Degree in a scientific health fieldRequires at least 2 years of on-site monitoring experience.Ability to establish and maintain positive relationships with Sponsor, Site and Project Team membersAbility to autonomously manage monitoring activitiesTECHNICAL COMPETENCES & SOFT SKILLSQuality focused; Proven ability to be careful, thorough, and detail-orientedStrong organizational skills and the ability to multi-task and work effectively in a fast-paced environmentAble to manage priorities, organize time and solve problemsStrong analytical, negotiation, meeting management, cross-functional team, and leadership skillsAbility to travelAbility to manage stressProfessional, trustworthy and disciplinedAbility to problem-solve unstructured or ambiguous challengesStrong command of Local language, both written and verbal, in the country where monitoring activities are performedExcellent communication and interpersonal skills with customer service orientationGood computer skills, with ability to use clinical trial management systems, clinical trial databases and electronic data captureSelf-starter who thrives in a collaborative, yet less structured team environmentKnowledge of clinical research, ICH GCP and local regulationsKnowledge of Regulatory and Ethical requirementsLanguagesEnglishEducationBachelor of Science (BS): Biology, Bachelor of Science (BS): Life SciencesContract TypeRegular

Responsibilities:

• Conduct experiments to support the development of analytical methods, evaluate method suitability, and troubleshoot analytical methods.
• Carry out chemical and physical analyses to support decisions related to drug substance process and formulation optimization, working closely with colleagues in Pharmaceutical Sciences.
• Address technical challenges related to methods developed internally and those established by external CDMO partners.
• Write and/or review reports and data generated from work performed
• Help coordinate and prioritize internal Analytical Development resources by collaborating with Analytical Development project representatives, Formulation Sciences, and Process Chemistry.
• Share scientific data and findings with cross-functional teams through presentations.
• Actively engage in the maintenance of laboratory instruments.

Skills:

• Proven understanding of analytical techniques such as HPLC, HRMS, GC, FT-IR, NMR, KF, Dissolution, PXRD, and/or familiarity with other methods commonly used in pharmaceutical analysis.

Education:

• B.S. in chemistry or a related discipline with 03 years of relevant experience, or M.S. with 01 years of experience.