Principal Investigator jobs involve leading 29,297 Principal Investigator jobs in the United States
Principal Investigator
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Who we are
We’re a global, midsize CRO that pushes boundaries, innovates and invents because the path to a cure for the world’s most persistent diseases is not paved by those who play it safe. It is built by those who take pioneering, creative approaches and implement them with quality and excellence.
We are Worldwide Clinical Trials, and we are a global team of over 3,500+ experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs – in the best possible way.
Our mission is to work with passion and purpose every day to improve lives and we are looking for others who value this same pursuit.
Why Worldwide
We believe everyone plays an important role in making a world of difference for patients and their caregivers. From our hands-on, accessible leaders, to our cohesive and supportive teams, we are committed to enabling professionals from all backgrounds and experiences to succeed. We prioritize cultivating a diverse and inclusive environment that continues to promote collaboration and creativity. We are proud to be a workplace where people thrive by being themselves and are inspired to do their best work every day. Join us!
What the Medical Director-Investigator does at Worldwide
- Ensures adherence to protocol requirements, protects the rights and welfare of subjects, assures the integrity of data generated at the site. The role directs the conduct of the clinical investigation according to federal and state regulations including guidance documents. Directly supervises all full-time, part-time, and PRN Investigators and Sub-Investigators. Indirectly supervises and oversees all clinical staff
What you will do
- Ensure protocol compliance
- Supports review by a duly constituted IRB
- Manage the medical care of subjects
- Protect the rights and welfare of subjects
- Ensure the validity of the data reported to sponsors
- Ensure documentation of study-related procedures, processes, and events
- Ensure the proper use and storage of investigational agents
- Support site operations
What you will bring to the role
- Minimum of 2 years’ experience in performing physicals, assessing, and treating patients.
- Strong supervision, interpersonal and communication skills.
- Must possess exceptional organizational and planning skills and good documentation skills.
- Must have good conflict resolution skills and be committed to quality.
- Must be punctual and have a flexible work schedule to include on call, weekends and holidays if needed
- At least 2 years’ experience in clinical research as an investigator or sub-Investigator.
- In-depth knowledge of the clinical research process, including Good Clinical Practices.
Your experience
- Required: Medical (M.D.) degree with at least 2 years of clinical research experience.
- Preferred: Medical degree plus at least 5 years of clinical research experience with 2 years in Phase 1 research.
We love knowing that someone is going to have a better life because of the work we do.
To view our other roles, check out our careers page at Discover a world of difference at Worldwide ! For more information on Worldwide, visit or connect with us on LinkedIn .
Principal Investigator
Posted 16 days ago
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Job Description
GovCIO is currently hiring for a Principal Investigation. This position will be located in Dayton OH, and will an onsite position.
**Responsibilities**
Lead the development of innovative research strategies, methodologies, and experimental designs to address critical ISR challenges.Foster a culture of scientific excellence and innovation, mentoring junior researchers and fostering interdisciplinary collaboration.
+ Oversee the planning, execution, and evaluation of research projects, ensuring deliverables are met on time, within budget, and to the highest quality standards.
+ Coordinate with cross-functional teams, including engineers, data scientists, and military liaisons, to integrate research findings into practical ISR systems and capabilities.
+ Manage project milestones, risk assessments, and reporting processes, providing regular updates to senior leadership and funding agencies.
+ Identify emerging trends, technologies, and methodologies in ISR and related fields; lead exploratory research to integrate cutting-edge innovations into current and future projects.
+ Develop and implement robust experimental frameworks and data analysis techniques to validate research outcomes
**Qualifications**
PhD with 5+ years, Medical Degree (or commensurate experience)
Required Skills and Experience:
+ 5+ years of postdoctoral or industry research experience, including a demonstrated track record of leading RDT&E projects, preferably within defense or ISR-related fields.
+ Proven experience as a Principal Investigator on federally funded research projects, with successful management of multi-million-dollar budgets and complex research teams.
+ Strong background in ISR technologies (e.g., sensor systems, data analytics, signal processing, autonomous systems) and familiarity with military research prioritiesexpertise in experimental design, data analysis, and advanced modeling/simulation techniques.Exceptional leadership, project management, and communication skills, with the ability to articulate complex technical concepts to diverse audiences.
+ Demonstrated ability to foster interdisciplinary collaboration and drive innovation in a fast-paced research environment
+ Clearance Required: TS/SCI
***pending contract award***
Preferred Skills and Experience:
+ Prior experience working directly with the Air Force Research Laboratory (AFRL) or similar defense research agencies.
+ A strong publication record in peer-reviewed journals and presentations at leading conferences.
+ Experience in technology transfer and commercialization of research outcomes.
+ Demonstrated success in mentoring and developing early-career scientists and engineers.
**Company Overview**
GovCIO is a team of transformers--people who are passionate about transforming government IT. Every day, we make a positive impact by delivering innovative IT services and solutions that improve how government agencies operate and serve our citizens.
But we can't do it alone. We need great people to help us do great things - for our customers, our culture, and our ability to attract other great people. We are changing the face of government IT and building a workforce that fuels this mission. Are you ready to be a transformer?
**What You Can Expect**
**Interview & Hiring Process**
If you are selected to move forward through the process, here's what you can expect:
+ During the Interview Process
+ Virtual video interview conducted via video with the hiring manager and/or team
+ Camera must be on
+ A valid photo ID must be presented during each interview
+ During the Hiring Process
+ Enhanced Biometrics ID verification screening
+ Background check, to include:
+ Criminal history (past 7 years)
+ Verification of your highest level of education
+ Verification of your employment history (past 7 years), based on information provided in your application
**Employee Perks**
At GovCIO, we consistently hear that meaningful work and a collaborative team environment are two of the top reasons our employees enjoy working here. In addition, our employees have access to a range of perks and benefits to support their personal and professional well-being, beyond the standard company offered health benefits, including:
+ Employee Assistance Program (EAP)
+ Corporate Discounts
+ Learning & Development platform, to include certification preparation content
+ Training, Education and Certification Assistance*
+ Referral Bonus Program
+ Internal Mobility Program
+ Pet Insurance
+ Flexible Work Environment
*Available to full-time employees
Our employees' unique talents and contributions are the driving force behind our success in supporting our customers, which ultimately fuels the success of our company. Join us and be a part of a culture that invests in its people and prioritizes continuous enhancement of the employee experience.
**We are an Equal Opportunity Employer.** All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender, gender identity or expression, sexual orientation, national origin, disability, or status as a protected veteran. EOE, including disability/vets.
**Posted Pay Range**
The posted pay range, if referenced, reflects the range expected for this position at the commencement of employment, however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, education, experience, and internal equity. The total compensation package for this position may also include other compensation elements, to be discussed during the hiring process. If hired, employee will be in an "at-will position" and the GovCIO reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, GovCIO or individual department/team performance, and market factors.
**Posted Salary Range**
USD $210,000.00 - USD $220,000.00 /Yr.
Submit a referral to this job ( _US-OH-Beavercreek_
**ID** _ _
**Category** _Intelligence Analysis & Operations_
**Position Type** _Full-Time_
Principal Investigator
Posted today
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Job Description
Description:
Summary
The Principal Investigator should be a highly-motivated and self-directed individual with a proven track-record of leveraging industrial R&D to commercialize new chemistry-based innovations. The Principal Investigator will have accountability to lead and grow a strategic technology platform for Halocarbon. The Principal Investigator will work with both the Commercial (Sales and Marketing) and Innovation Team (Scientists) to create research and technology strategies focused on the development and commercialization of new products based on market insights, competitive intelligence, and customer/partner feedback and guidance. The Principal Investigator will be required to stay current with major thursts in the technological and industrial domains pertinent to Halocarbon and will be responsible to develop and manage a multi-generational innovation pipeline. The Principal Investigator is a leadership position within the Halocarbon organization and will require the individual to be a champion of Halocarbon vision and core values, both within the company and to the industry. The Principal Investigator will be responsible for developing and managing Halocarbon IP strategy. The Principal Investigator needs to have strong business acumen and a strategic mindset with an established track-record of having leveraged expertise within a technical domain (organic chemistry, polymer chemistry, materials science, engineering, etc.) to have an impact on business growth and direction. This individual will be a valued member of the broad Halocarbon management team, and will be expected to lead high-visibility cross-functional programs and communicate to all levels of leadership, both within and outside of Halocarbon.
Duties and Responsibilities
- Work with Commercial Team to plan to build multi-generational research plans aimed at growing business in strategic industries and markets
- Develop research programs and build business cases to effectively resource and staff research projects to effectively meet commercial goals and timelines
- Develop product portfolios and value propositions by leveraging internal and external resources
- Manage research team member(s) to effectively drive laboratory chemistry and production scale-up
- Create product development strategy and enrich multi-generational innovation pipeline
- Establish domain expertise in technology and industry/application (individually and for Halocarbon)
- Conduct practical experiments (bench chemistry) as needed to evaluate and guide new research directions
- Lead multiple projects through stage gate process (accountable for defining and meeting technical milestones)
- Lead cross-functional teams to drive product development and commercialization
- Lead customer interactions to identify and manage key influencers and decision makers for product adoption
- Research and develop new product concepts and ideas based on technical and market information
- Propose research programs and new research platforms with business cases for staffing and investment
- PhD in Chemistry (organic, polymer, materials science), 6+ years of industrial experience in product development and commercialization or, MS in Chemistry with MBA
- Project management experience a must
- People management experience a must
- Experience in product development a must
- Experience with handling all lab equipment in a safe and responsible manner
- Able to use statistical methods to analyze data desired
- Organize/analyze generated data and prepare recommendations based on project requirements
- Computer knowledge required including proficiency with Microsoft Office, ChemDraw, SciFinder, PatSnap, etc.
*Halocarbon is an Equal Opportunity Employer.
Principal Investigator - 245392
Posted today
Job Viewed
Job Description
This is an opportunity to work as a principal investigator (clinical research physician) at a clinical research site in Decatur, GA. At this site they perform industry sponsored clinical research trials on a variety of conditions including weight loss for obesity, chronic pain, and migraines among others.
- Currently open to both full time and part time applicants
- Open to a variety of specialties including neurology, psychiatry, internal medicine, cardiology, and endocrinology
- On-site opportunity, standard business hours Mon - Fri
- Previous principal investigator experience is required
Job Summary:
- Responsible for conducting clinical trials in accordance with the research protocol, Good Clinical Practices (GCPs), and federal/state regulations.
- Generates independent, high quality, and reproducible results.
- Collaborate with our study team, as well as various medical, pharmaceutical company and regulatory personnel to ensure the health and welfare of study participants.
- Responsible for the management and integrity of the design, conduct, and reporting of the research project and for managing, monitoring, and ensuring the integrity of any collaborative relationships.
- Responsible for the direction and oversight of compliance, financial, personnel, and other related aspects of the research project
Principal Investigator - 245392
Posted today
Job Viewed
Job Description
This is an opportunity to work as a principal investigator (clinical research physician) at a clinical research site in Charlottesville VA. At this site they perform industry sponsored clinical research trials on a variety of conditions asthma, anxiety, COPD, depression, and diabetes among others.
- Currently open to both full time and part time applicants
- Open to a variety of specialties including neurology, psychiatry, cardiology, and endocrinology
- On-site opportunity, standard business hours Mon - Fri
- Previous principal investigator experience is required
Job Summary:
- Responsible for conducting clinical trials in accordance with the research protocol, Good Clinical Practices (GCPs), and federal/state regulations.
- Generates independent, high quality, and reproducible results.
- Collaborate with our study team, as well as various medical, pharmaceutical company and regulatory personnel to ensure the health and welfare of study participants.
- Responsible for the management and integrity of the design, conduct, and reporting of the research project and for managing, monitoring, and ensuring the integrity of any collaborative relationships.
- Responsible for the direction and oversight of compliance, financial, personnel, and other related aspects of the research project
Archaeologist, Principal Investigator
Posted 1 day ago
Job Viewed
Job Description
This position involves providing desktop and field-based cultural resources support for planning, engineering, and construction services to
government, military, and commercial clients. The archaeologist career path provides the opportunity to work on projects that require compliance with the National Historic Preservation Act (NHPA), Archaeological Resources Protection Act (ARPA), National Environmental Policy Act (NEPA), Native American Graves Repatriation and Protection Act (NAGPRA), and other federal, state, and local cultural resource regulations.
Based out of Sacramento, you'll serve as a key team member working with scientists, engineers, project managers, and other project staff across business sectors and practices in the company; interface with clients; and coordinate consultation with State Historic Preservation Officers, the Advisory Council on Historic Preservation, Native American tribes, and multiple state and federal agencies. You'll conduct coordinate, and oversee archaeological fieldwork, including Phases I-III studies and archaeological monitoring; analyze project impacts as part of Section 106 and other regulations; analyze and interpret data; write and review cultural resources technical reports; develop archaeological treatment plans and agreement documents; and evaluate eligibility of resources for listing in the National Register of Historic Places (NRHP) and state registers. You will also prepare proposals, provide technical reviews of deliverables, provide technical guidance to junior and mid-level employees, and serve as a mentor within the cultural resources group.
- Master's degree in Archaeology, Anthropology, or a related field
- Meet Secretary of the Interior's Professional Qualifications Standards for
Archaeology
- Minimum of 8 years of professional archaeological fieldwork, project oversight, and reporting
- Experience as a Principal Investigator
- Experience working in the consulting environment and ability to handle multiple projects simultaneously and be responsive to both internal and external clients
- Knowledge of historic preservation laws and policies, including NEPA, NHPA, ARPA, and NAGPRA
- Must be capable of walking for long periods of time over unfamiliar
terrain, excavating shovel tests and test units, screening soil, and carrying field equipment
- Must be willing and able to travel frequently and for long
periods of time, as needed
- Experience using GPS technology
- Proficiency with Microsoft Office Suite
- Excellent oral and written communication
skills
- Experience working with tribal groups
Ideally, You'll Also Have:
- A Registered Professional Archaeologist designation
- Experience completing cultural resources studies for infrastructure, electrical transmission, federal agencies, renewable
energy, and/or remediation projects
- Experience leading projects from proposal to submittal, including preparing scopes of work, budgets, writing reports, consulting with interested parties, and resolving concerns
- Existing relationships with the tribal community
#LI-AC4
Jacobs is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, religion, creed, color, national origin, ancestry, sex (including pregnancy, childbirth, breastfeeding, or medical conditions related to pregnancy, childbirth, or breastfeeding), age, medical condition, marital or domestic partner status, sexual orientation, gender, gender identity, gender expression and transgender status, mental disability or physical disability, genetic information, military or veteran status, citizenship, low-income status or any other status or characteristic protected by applicable law. Learn more about your rights under Federal EEO laws and supplemental language.
Archaeologist, Principal Investigator
Posted 1 day ago
Job Viewed
Job Description
This position involves providing desktop and field-based cultural resources support for planning, engineering, and construction services to
government, military, and commercial clients. The archaeologist career path provides the opportunity to work on projects that require compliance with the National Historic Preservation Act (NHPA), Archaeological Resources Protection Act (ARPA), National Environmental Policy Act (NEPA), Native American Graves Repatriation and Protection Act (NAGPRA), and other federal, state, and local cultural resource regulations.
Based out of Sacramento, you'll serve as a key team member working with scientists, engineers, project managers, and other project staff across business sectors and practices in the company; interface with clients; and coordinate consultation with State Historic Preservation Officers, the Advisory Council on Historic Preservation, Native American tribes, and multiple state and federal agencies. You'll conduct coordinate, and oversee archaeological fieldwork, including Phases I-III studies and archaeological monitoring; analyze project impacts as part of Section 106 and other regulations; analyze and interpret data; write and review cultural resources technical reports; develop archaeological treatment plans and agreement documents; and evaluate eligibility of resources for listing in the National Register of Historic Places (NRHP) and state registers. You will also prepare proposals, provide technical reviews of deliverables, provide technical guidance to junior and mid-level employees, and serve as a mentor within the cultural resources group.
- Master's degree in Archaeology, Anthropology, or a related field
- Meet Secretary of the Interior's Professional Qualifications Standards for
Archaeology
- Minimum of 8 years of professional archaeological fieldwork, project oversight, and reporting
- Experience as a Principal Investigator
- Experience working in the consulting environment and ability to handle multiple projects simultaneously and be responsive to both internal and external clients
- Knowledge of historic preservation laws and policies, including NEPA, NHPA, ARPA, and NAGPRA
- Must be capable of walking for long periods of time over unfamiliar
terrain, excavating shovel tests and test units, screening soil, and carrying field equipment
- Must be willing and able to travel frequently and for long
periods of time, as needed
- Experience using GPS technology
- Proficiency with Microsoft Office Suite
- Excellent oral and written communication
skills
- Experience working with tribal groups
Ideally, You'll Also Have:
- A Registered Professional Archaeologist designation
- Experience completing cultural resources studies for infrastructure, electrical transmission, federal agencies, renewable
energy, and/or remediation projects
- Experience leading projects from proposal to submittal, including preparing scopes of work, budgets, writing reports, consulting with interested parties, and resolving concerns
- Existing relationships with the tribal community
#LI-AC4
Jacobs is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, religion, creed, color, national origin, ancestry, sex (including pregnancy, childbirth, breastfeeding, or medical conditions related to pregnancy, childbirth, or breastfeeding), age, medical condition, marital or domestic partner status, sexual orientation, gender, gender identity, gender expression and transgender status, mental disability or physical disability, genetic information, military or veteran status, citizenship, low-income status or any other status or characteristic protected by applicable law. Learn more about your rights under Federal EEO laws and supplemental language.
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Principal Investigator, MD
Posted today
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Job Description
Job Description
Reports to: Medical Director
Join Us at Civia Health
At Civia Health, we’re reimagining how clinical trials are delivered—by putting patients first and empowering providers to lead innovation. We’re seeking an experienced and compassionate Principal Investigator (PI) to oversee Phase 2–4 clinical trials in a collaborative, mission-driven environment. You’ll play a vital role in ensuring scientific integrity, patient safety, and regulatory compliance while contributing to groundbreaking research.
At Civia Health, you're not just taking a job: You're joining a mission to transform the way clinical research is done. Our purpose is bold: to bring clinical trials front and center in your community, make them accessible to everyday people, and empower underrepresented communities to participate.
We’re reinventing how clinical studies are run, delivering valid, scalable evidence with a consumer-first mindset. Too often, trials are expensive, fragmented, and overlook the experience of the participant. At Civia, we’re changing that. Our leadership team are experienced industry leading, visionary professionals who know what’s broken — and how to fix it.
We treat participants like valued partners, not research subjects. That means supporting their agency, putting their needs, comfort, and enjoyment first — and rewarding them generously for their time and effort.
What It Means to Work at Civia
Every team member plays a crucial role in reshaping clinical research. You’ll help make studies more human-centered, inclusive, and efficient. We're looking for people who are driven by purpose, inspired by innovation, and ready to roll up their sleeves to do meaningful work.
At Civia, your contributions aren’t just transactional, they’re transformational.
What You’ll Do
Serve as the physician of record and lead clinical oversight for assigned trials.
Review and approve study protocols, informed consent documents, and source documentation.
Conduct physical exams, medical reviews, and oversee safety assessments for participants.
Ensure compliance with all ICH-GCP, FDA, and IRB regulations.
Provide guidance and mentorship to the clinical research team.
Engage with sponsors, monitors, and regulatory bodies as needed.
Occasional travel may be required for audits, site visits, or team meetings.
What You Bring
Medical degree (MD or DO) with active and unrestricted license.
3+ years of experience as a Principal Investigator in clinical research (Phase 2–4 preferred).
Board certification in internal medicine, endocrinology, or related field preferred.
Strong working knowledge of GCP, FDA regulations, and clinical operations.
Excellent leadership, communication, and problem-solving skills.
Passion for innovation, ethics, and patient-centered care.
What We Offer
Competitive compensation
Medical, dental, and vision insurance
Generous PTO and paid holidays
Flexible scheduling options
Professional development and continuing education support
A mission-driven team that values respect, inclusion, and innovation
Ready to Make an Impact?
Mission with Meaning: Be part of a purpose-led team committed to health equity and real-world impact.
Startup Energy, Proven Expertise: Work fast, adapt quickly, and help build something new; guided by seasoned visionary professionals who’ve seen what needs to change.
People First Culture: We care deeply about our patients, participants, and each other. Collaboration, transparency, and bold, straight-talking are core to how we work.
Invested in Your Growth: We don’t just hire for today; we’re building the leaders and changemakers of tomorrow.
If you’re ready to be part of something meaningful—and work with people who care deeply about doing good work—apply today by submitting your resume and cover letter to the link above. We’re excited to learn more about you!
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Principal Investigator - 245392
Posted today
Job Viewed
Job Description
This is an opportunity to work as a principal investigator (clinical research physician) at a clinical research site in Decatur, GA. At this site they perform industry sponsored clinical research trials on a variety of conditions including weight loss for obesity, chronic pain, and migraines among others.
- Currently open to both full time and part time applicants
- Open to a variety of specialties including neurology, psychiatry, internal medicine, cardiology, and endocrinology
- On-site opportunity, standard business hours Mon - Fri
- Previous principal investigator experience is required
Job Summary:
- Responsible for conducting clinical trials in accordance with the research protocol, Good Clinical Practices (GCPs), and federal/state regulations.
- Generates independent, high quality, and reproducible results.
- Collaborate with our study team, as well as various medical, pharmaceutical company and regulatory personnel to ensure the health and welfare of study participants.
- Responsible for the management and integrity of the design, conduct, and reporting of the research project and for managing, monitoring, and ensuring the integrity of any collaborative relationships.
- Responsible for the direction and oversight of compliance, financial, personnel, and other related aspects of the research project
Principal Investigator - 245392
Posted today
Job Viewed
Job Description
This is an opportunity to work as a principal investigator (clinical research physician) at a clinical research site in Charlottesville VA. At this site they perform industry sponsored clinical research trials on a variety of conditions asthma, anxiety, COPD, depression, and diabetes among others.
- Currently open to both full time and part time applicants
- Open to a variety of specialties including neurology, psychiatry, cardiology, and endocrinology
- On-site opportunity, standard business hours Mon - Fri
- Previous principal investigator experience is required
Job Summary:
- Responsible for conducting clinical trials in accordance with the research protocol, Good Clinical Practices (GCPs), and federal/state regulations.
- Generates independent, high quality, and reproducible results.
- Collaborate with our study team, as well as various medical, pharmaceutical company and regulatory personnel to ensure the health and welfare of study participants.
- Responsible for the management and integrity of the design, conduct, and reporting of the research project and for managing, monitoring, and ensuring the integrity of any collaborative relationships.
- Responsible for the direction and oversight of compliance, financial, personnel, and other related aspects of the research project