5,621 Principal Investigator jobs in the United States

Job Description

NCE is actively recruiting an experienced Principal Investigator to join our Pavements and Materials Group. If you enjoy a challenging career in applied pavement research, this opportunity may be for you!

Examples of research interests include design, performance, sustainability, and resiliency, of either asphalt or concrete pavements. NCE does not have in-house laboratory facilities but regularly interprets and applies test results (by others) as part of ongoing applied research efforts.

You should have a proven track record of successful research projects, project management, strong client skills, writing and winning research proposals, as well as implementing research results. You will work with NCE staff to win new research projects and bring together the resources that will assure the high-quality outcomes NCE delivers. Continued participation on national committees (e.g., TRB, ASTM, ACPA, AAPT) is highly encouraged. The ability to increase NCE’s visibility on the State and National level in your areas of technical expertise is a must, which will include business development and client interaction (including travel). Relocation to an NCE office location is preferred, but not required.

Qualifications (Must Have):

• Ph.D. in a pavement-related field with 15+ years of experience.
• B.S. or M.S. with 20+ years of experience as a PI in applied pavement research.
• Proven record of leading applied research projects in the PI or Co-PI role, including projects >$500,000.
• Demonstrated ability to lead and manage multiple projects.
• Demonstrated ability to prepare successful proposals and win projects.
• Excellent communication skills (written and verbal).

Qualifications (Nice to Have):

• Extensive network of industry colleagues at State and Federal agencies.
• Professional Engineer registration (any state), or ability to obtain within 6 months of hiring.
• Ability to support NCE’s engineering assignments by providing technical input.
• Ability to mentor and supervise engineering staff.

Working Conditions: Mainly office setting, travel as required, field visits as needed.

Salary Range: $20,000 to 180,000+ annually, DOE.

Job Description

Description:

Job Title: Principal Investigator (PI) – Dementia Clinical Trial (Very Part-Time)
Organization: RRPA (River Region Psychiatry Associates)
Location: Remote/Hybrid (Community-based partnerships in select areas)
Time Commitment: 1–2 hours per week
Compensation: Stipend plus a percentage

Position Summary:
RRPA (River Region Psychiatry Associates) is seeking a licensed psychiatrist or neurologist to serve as Principal Investigator (PI) for a community-based clinical trial focused on dementia and associated psychiatric health disparities. This very part-time role is ideal for clinicians interested in contributing to meaningful, grant-funded and industry-supported research with minimal weekly time commitment.

The successful candidate will oversee research aimed at improving mental health outcomes and care delivery for individuals with chronic psychiatric conditions, particularly in underserved communities. Reporting directly to the Chief Operating Officer, the PI will work with a multidisciplinary team and external academic and community partners.

Key Responsibilities:

• Lead and oversee the design, implementation, and analysis of clinical and community-based research focused on dementia and psychiatric health disparities
  
• Ensure full compliance with study protocols, IRB guidelines, GCP, HIPAA, and FDA requirements
  
• Conduct patient procedures and clinical trial visits as required by the protocol
  
• Translate behavioral science findings into practical, scalable mental health interventions
  
• Collaborate with academic institutions, community organizations, and healthcare systems locally and nationally
  
• Mentor junior investigators and research staff
  
• Maintain complete and accurate documentation of all trial activities
  
• Support community outreach efforts and contribute to organizational strategic initiatives
  
• Disseminate findings through presentations, reports, and publications
  
• Keep current with emerging research in behavioral and psychiatric science
  
• Maintain up-to-date licensure, CV, and continuing education for study participation
  

Time Commitment:

• 1–2 hours per week
  
• Flexible schedule; mostly remote with limited in-person engagement as needed
  

To Apply:
Please send your CV

Qualifications:

• Board-certified psychiatrist or neurologist
• Active, unrestricted U.S. medical license
• Experience in clinical trials and/or community-based research (preferred)
• Commitment to addressing health disparities and improving mental health care access
• Familiarity with GCP, HIPAA, and clinical trial regulations

Experience

• Proven track record in psychiatric or behavioral health research, with experience obtaining and managing externally funded protocols, preferably pharmaceutical-sponsored.
• Demonstrated expertise in community-based participatory research, health disparities, or chronic psychiatric conditions.
• Experience with qualitative, mixed methods, or multidisciplinary research approaches.
• Strong leadership, collaboration, and communication skill

Job Description

Location: Monday - Friday / on-site/ Inglewood, CA

Company Overview: At Alliance Clinical Network we're people with a purpose, dedicated to advancing medical innovation and healing technology through groundbreaking research. We bring our energy and our passion to improving patient lives every day.

Position Overview: We are seeking a highly skilled and experienced Principal Investigator medical physician to join our team. As the Principal Investigator, you will be responsible for oversight of all clinical trial studies according to study protocols, company processes and GCP.

This is a part-time position with flexible hours, ranging from 20 to 30 hours per week. The exact hours will vary based on the needs of the clinical trial study, offering both adaptability and the opportunity to work on a dynamic and engaging project.

Responsibilities:
- Ensure the medical safety of study participants.

- Oversee site personnel in the execution and delivery of safe trial practices.

- Review and report on screening failures, safety and participant retention rates.

- Oversee clinical evaluation and assessments of clinical trial studies.

- Interface with IRBs and study Sponsors on a regular basis.

- Comply with all medical duties per study protocols, SOP, GCP and state regulations.

- Collect and analyze data to identify patterns or trends of the clinical trials.

- Prepare detailed reports documenting findings and recommendations for improvement.

- Stay up-to-date with the latest developments in SOPs and documentation requirements.

Qualifications:
- Active and unrestricted Medical License - California.

- 2 years experience as a Principal Investigator of Sub-Investigator, preferred. Although we are willing to train the right candidate.

- Strong analytical skills with the ability to collect, analyze, and interpret complex data.

- Excellent written and verbal communication skills for report writing and presenting findings.

- Ability to effectively manage a team and prioritize tasks in a fast-paced environment.

- Attention to detail and ability to maintain confidentiality when handling sensitive information.

If you are a highly motivated individual with a passion for clinical research, we encourage you to apply for this position.

Education:

• Doctorate (Required)

Job Description

The START Center for Cancer Research (“START”) is the world’s largest early phase site network, fully dedicated to oncology clinical research. Throughout our history, START has provided hope to cancer patients in global community practices by offering access to cutting edge trials throughout the US and Europe. Today, with over 1,300 studies completed, and with research facilities in the United States and in Spain, Portugal, and Ireland, START’s mission is to accelerate the development of new anticancer drugs that will improve the quality of life and survival for patients with cancer and lead to its eventual cure. To date, over 43 therapies conducted at START locations have obtained FDA/EMA approval. Incredibly, while Academic Medical Centers (AMCs) conduct 80% of cancer trials, such trials reach only 20% of the patient population – leaving the majority of patients who are treated in community practices and hospitals without access to a clinical trial when their care journey calls for one. START serves the many – by bringing cancer trials to physicians and their patients in community hospitals and practices when hope is needed most.

START represents the world’s largest roster of Principal Investigators (PIs) across its eight clinical trial sites. Committed to accelerating passage from trials to treatments, START delivers hope to patients, families, and physicians around the world. As an example, in San Antonio, where START was founded, START treated the first patient ever with Keytruda – the most effective cancer drug in medical history.

We are seeking a Clinical Principal Investigator. The Clinical Principal Investigator (PI) is a physician-scientist responsible for the overall preparation, conduct, and management of sponsored projects, ensuring compliance with all regulatory requirements and institutional policies. This role will manage the development and execution of clinical trial protocols, contribute to data analysis, and maintain strong communication and alignment with sponsors.

This role is based on site in Myrtle Beach, South Carolina.

Essential Responsibilities

• Manage early phase clinical trials by providing overarching medical direction and comprehensive medical reviews of protocols in conformance with the investigational plan and good clinical practice.
• Provide medical and scientific feasibility of all new sponsor inquiries driving growth through strategic partnerships.
• Lead and manage a matrix team of responsible for responsible for the conduct of early phase oncology trials.
• Ensure the safety and well-being of all participants in the study at the trial site are protected.
• Ensure data collected at the study site is credible and accurate.
• Ensure the rights, integrity, and confidentiality of all participants in the trial at the site are protected.
• Develop close personal working relationships with Sponsors and Clinical Research Organizations involved in study conduct.
• Provide expert guidance and support to clinical operations research staff and sponsor client.
• Lead continuous quality improvement efforts for clinical research services, integrating best practices and fostering a culture of research excellence.
• Develop and implement strategies to enhance patient recruitment and retention in clinical trials.

Required Education and Experience:

• M.D. or equivalent.
• Board Certified in Hematology and/or Medical Oncology.
• Clinical trials experience with a strong interest in drug development.
• Ability to critically analyze clinical scientific data and literature.
• Understanding of GCP principles, safety and adverse event reporting, FDA regulations, and biomedical research ethics.
• A passion for providing excellent clinical care and for working in a collaborative / team-oriented environment.

Preferred Education and Experience:

• Previous experience with industry sponsored clinical trials.
• Excellent communication skills, with experience in publishing and presenting at scientific meetings.
• Translational research experience and familiarity with pharmacokinetics and pharmacodynamics.

Best-in-Class Benefits and Perks
We value our employees’ time and efforts. Our commitment to your success is enhanced by a competitive compensation, depending on experience, and an extensive benefits package including:

• Comprehensive health coverage: Medical, dental, and vision insurance options provided
• Robust retirement planning: 401(k) plan available with employer matching
• Financial security: Company-paid life and disability insurance for added protection
• Flexible financial options: Health savings and flexible spending accounts offered
• Well-being and work-life balance: Paid time off, flexible schedule, and remote work choices provided
• Plus, we work to maintain the best environment for our employees, where people can learn and grow with the company. We strive to provide a collaborative, creative environment where everyone feels encouraged to contribute to our processes, decisions, planning, and culture.

More about The START Center for Cancer Research
Deeply rooted in community oncology centers globally, The START Center for Cancer Research provides access to specialized preclinical and early-phase clinical trials of novel anti-cancer agents. START clinical trial sites have conducted more than a thousand early-phase clinical trials, including for 43 therapies that were approved by the FDA. START represents the world’s largest roster of Principal Investigators (PIs) across its eight clinical trial sites. Committed to accelerating passage from trials to treatments, START delivers hope to patients, families, and physicians around the world. Learn more at STARTresearch.com.

Ready to be part of a team changing the future of cancer treatment?
Join us in our mission to conquer cancer, one clinical trial at a time. Your expertise and dedication can help us bring hope and healing to patients worldwide. Please submit your application online.

We are an equal opportunity employer that welcomes and encourages diversity in the workplace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.