14,227 Research jobs in the United States

At Client, we are inspired by a single vision – transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

The Oncogenesis Thematic Research Center (TRC) at Client is one of the fundamental research and early development engines delivering therapeutics to cancer patients, integrating early discovery research through translational and early clinical development. Our modality focuses on numerous aspects of protein homeostasis including the ubiquitin-proteasome system, protein translation, and RNA processing and stability allowing the group to capitalize on the cutting edge science that underpins the action of the company's most advanced drugs. Pioneering research around these modalities creates a very dynamic, exciting and creative environment that exploits excellent science in biology, biochemistry, structural biology, computational biology and translational development.

The Discovery Biology Department within the Oncogenesis (TRC) focuses on delivering Client cancer therapeutics by engaging E3 ubiquitin ligases for targeted protein degradation. We are seeking a highly motivated Scientist with strong background in tumor biology and understanding of the ubiquitin-proteasome system (UPS) to participate in the discovery of Client targeted protein degradation drugs for hematology and solid tumor oncology projects. The successful candidate will work collaboratively in a multi-disciplinary environment to:

1. Explore disease biology enabling identification of Client drug targets;
2. Develop and implement robust cellular assays to support discovery of small molecules as clinical development candidates;
3. Design and execute research strategies that further our understanding of the mechanisms of Client compounds and targets;
4. Support for lab operations that will include assistance in maintaining the liquid nitrogen cell database and site compliance.

Responsibilities will include, but are not limited to:

• Work independently to design, execute, analyze, interpret and troubleshoot scientific experiments in molecular and cell biology, cellular biochemistry and assay development.
• Contribute to computational analyses that leverage internal, public and partner datasets and empower data-driven decisions for new target prioritization and validation.
• Accurately maintain written reports and present results in an organized and timely manner to research leadership.
• Communicate effectively with peers and supervisors, foster teamwork and contribute to collaborative efforts.
• Strong commitment to quality and demonstrate adaptability.

Skills/Knowledge Required:

• Extensive experience designing, implementing and analyzing compound effect using multiple platforms (multi-parameter flow cytometry, IncuCyte, Western blot, ELISA/MSD, and functional assays such as cytotoxicity, cell cycle and apoptosis) in the context of drug discovery is required.
• Hands-on experience in mammalian cell culture using primary, single and/or co-culture cell models, including genetic manipulation techniques such as CRISPR RNP nucleofection and/or lentiviral transduction. Experience with 3D/organoid solid tumor models is a plus.
• Experience with HTS screening and the use of automation instruments is desired.
• Flexibility and interest in learning new techniques and skills in accordance with the research program needs.
• Proficiency in scientific and data analysis programs including FlowJo, Microsoft Excel, PowerPoint, GraphPad Prism is required.
• Ability to work in a fast-paced dynamic team environment; flexibility to adapt to changes with a positive attitude and independently collaborate across teams, requiring excellent communication skills, both written and verbal, with strong interpersonal skills.

PREREQUISITES

Ph.D. level in cell biology, immunology, molecular biology or equivalent field with 0-3 years of experience, or M.S. degree with a minimum of 4-6 years of experience or BSc with a minimum of 6-8 years of experience in biopharmaceutical industry developing and optimizing cell-based assays. The position level will be dependent on experience.

Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community.

Job Summary

This position involves performing scientific research work in testing ways to improve Machine Learning performance in a wide range of problems based on learning from hints, in particular, the use of virtual examples and dynamic schedules. The successful candidate will collaborate with the Abu Mostafa Research Group on this short-term project.

• Organize, plan, and conduct complex theoretical and experimental research in the use of hints in Machine Learning.
• Apply scientific knowledge to develop the full algorithm for using Generative Adversarial Networks to generate virtual examples for training neural-network models.
• Investigate, analyze, and interpret the use of dynamic schedules in learning from hints.
• Utilize Kaggle competitions to test the algorithm's performance.

Basic Qualifications

• Bachelor's degree in Computer Science or related field.
• Thorough technical/scientific expertise in Machine Learning theory and algorithms.
• Advanced Machine Learning project experience.

Preferred Qualifications

• Knowledge and proficiency in Python programming.
• Facility with Caltech's High-Performance Computing.

Required Documents

• Resume

$23.50 to $30.25 per hour

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, or national origin, disability status, protected veteran status, or any other characteristic protected by law.

The Oncology Discovery team at the Oncogenesis Thematic Research Center is seeking a Research Associate to support our drug discovery and characterization efforts. An early-career level position. Familiarity with core industry and lab practices and standards. Solves routine problems of limited scope and complexity. The qualified candidate will leverage various CRISPR/Cas9 technologies to enable genetic screens to support early and late-stage drug mechanism of action studies. They will assist senior team members in performing the totality of the screening process, including cell line generation, cell treatment experiments, NGS library preparation, and target validation. Common skills and techniques used will include mammalian cell culture, DNA/protein isolation, PCR, and western blot.

The successful candidate will demonstrate strong verbal and written communication skills and will be capable of working collaboratively in a multidisciplinary environment. 1-3 years wet lab research experience required; post-undergraduate lab experience desired; no PhD candidates.

This position is in San Diego, CA, 100% on-site, lab-based role.

1. Bachelor's degree in a scientific discipline (no PhD candidates)
2. 1-3 years of wet lab research experience and basic knowledge of cancer biology
3. Experience in mammalian cell culture and cell-based assays
4. Basic molecular biology skills, including PCR and western blotting, highly preferred
5. Ability to multi-task and prioritize time management of daily activities to deliver timely results
6. Excellent organizational skills and record-keeping
7. Excellent oral and written communication skills, proficiency in Excel and PowerPoint

1. Design research protocols in collaboration with senior researchers
2. Execute existing cellular and molecular biology protocols in the laboratory
3. Maintain cancer cell lines and establish new stable lines via lentiviral transduction
4. Perform genetic targeting using CRISPR/Cas9 technology for cell line characterization and screening, including studies performed on a genome-wide scale
5. Conduct routine molecular and cellular experiments including gDNA and RNA isolation, PCR, cloning, western blot analysis, flow cytometry, and microplate cell proliferation assays
6. Identify experimental issues, troubleshoot, and recommend a corrective course of action
7. Record data in electronic notebook in accordance to company policy
8. Communicate results in written and oral presentations

Life Sciences, Norman W. Church Laboratory for Chemical Biology, Pasadena, California, United States of America Req #10

Friday, April 25, 2025

Carnegie Science is dedicated to scientific exploration to advance investigation, research, and discovery, and apply that knowledge for the improvement of humankind.

Position Summary :

The Cao Lab ( at Carnegie Institution for Science, division of biosphere sciences and engineering ( ), located on the Caltech campus in Pasadena, CA. We seek one self-motivated and highly responsible research technician to join our team. Our lab focuses on the symbiosis between the insect-parasitic nematode Steinernema hermaphroditum and its mutualistic bacterium Xenorhabdus griffiniae . The technician aims to facilitate the development of genetic and synthetic biology tools to uncover the molecular mechanisms underlying nematode-bacteria communication and explore their applications in biosphere engineering.

The selected candidates will be joining a start-up laboratory within a larger research community, with many opportunities to present their work and interact with Carnegie and Caltech. Dr. Cao is committed to the professional development of all hires, with opportunities available to participate in scientific writing, mentorship, and outreach activities. Depending on the funding availability, hires also may have opportunities to attend and present their research at conferences.

This is a full-time and wet-lab position offering a competitive salary and benefits. We are looking to fill this role starting in the summer of 2025. This position is one year with possibilities of extension based on performance and the availability of the position.

This position is ideal for candidates with prior experience as a lab technician or in an equivalent research role. Candidates who recently graduated (or will be) graduating from college are encouraged to apply too.

Essential Functions:

Assist the Principal Investigator (PI) in managing the laboratory.

Support postdoctoral researcher and student in their research projects.

Manage multiple tasks in a small research group. Including performing laboratory procedures, maintaining accurate records, and contributing to the overall lab operations.

Maintain a predictable work schedule and execute assigned tasks reliably.

Exhibit critical thinking, problem-solving skills, and teamwork.

Prepare solutions and reagents for the lab.

Conduct essential and routine laboratory procedures, including animal and bacteria maintenance, sample preparation, record-keeping, analysis, and interpretation of results.

Assist the PI in managing lab purchases and organization.

Operate, maintain, and troubleshoot laboratory equipment as needed.

• Collaborate with and support other lab personnel on research projects.

Maintain a safe and clean laboratory environment by following proper safety protocols.

Participate in training and professional development to stay current in the field.

Maintain strict compliance of animal husbandry protocols and Caltech IACUC standards.

Train others as needed on animal facility and husbandry duties.

Prepare solutions and reagents for the lab.

Animals and bacteria maintenance, sample preparation, record-keeping, analysis, and interpretation of results.

Minimum Qualifications:

Currently enrolled in or holding a degree in molecular biology, microbiology, genetics, biochemistry, synthetic biology, or a related scientific field.

Prior laboratory experience especially in animal maintenance and a track record of managing wet-lab responsibilities.

Preferred Qualifications:

Expertise in molecular cloning (prefer experience in synthetic biology).

Experience working with emerging model organisms.

Knowledge/Skills/Abilities:

Awareness of the critical aspects of laboratory safety

Resilience in technology development

Detail oriented, highly organized, and highly responsible

Excellent written and oral communication skills

Critical thinking

Problem solving

Ability to work independently and as part of a team.

Compliance to laboratory guidelines.

Physical Demands/Working Conditions:

Routinely stoops and bends

Routinely reaches and grasps with arms and hands above head

Routinely stands for long periods

Occasionally lifts, pushes and/or carries objects weighing up to 60 pounds

Routinely is in contact with wet lab materials

Carnegie Institution for Science is an equal employment opportunity employer. All applicants will receive consideration of employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, veteran status or any other characteristic protected by applicable federal, state, or local laws.

• Life Sciences, Norman W. Church Laboratory for Chemical Biology, Pasadena, California, United States of America

Job Title: Associate Research Scientist
Location: San Diego, CA ONSITE (Schedule will vary. CW may be required to work a Saturday, and some days hours will be around 10:00am-6:00pm)

Top Skills:

1. Experience working in a BSL2+ environment.
2. Experience with human biospecimens (Preferred)
3. Excellent organizational skills and attention to detail
4. A B.S. degree in a scientific discipline with >2 years research experience (experience in the biotech or pharmaceutical industry preferred).

Position Summary:
Participate as part of the Oncogenesis PD assay team (CITRE and US) in processing of patient samples, control storage of vials and deliver sample to analysis teams to provide data in different clinical trials.

Key Responsibilities:

1. Support in providing timely PD data during Phase I trials from ONC-TRC to support
2. Accountable for planning, coordinating, and processing of clinical samples within the guidelines set by established clinical trial protocols
3. Responsible for chain of custody documentation for samples, including entry of key data elements into internal databases
4. Collaborate with the clinical sample management team to deliver samples to analysis teams for timely data reporting
5. Identification and escalation of issues to clinical trial points of contact to ensure resolution
6. Organize inventory of patient samples. Enter and update database information for different clinical trials
7. Organize stock of reagents
8. Keep a record of the batches of reagents used with each patient sample

Qualifications & Experience:

1. A B.S. degree in a scientific discipline with >2 years research experience (experience in the biotech or pharmaceutical industry preferred).
2. Excellent organizational skills and attention to detail
3. Experience working in a BSL2+ environment
4. Hands-on experience working with primary cell cultures and immortalized cell lines
5. Knowledge of clinical trials and biomarkers
6. Flexible to adapt to changing work assignments
7. Ability to collaborate with scientists, vendor labs, and other internal team players
8. Good Computer skills (mainly Microsoft Office package and databases)
9. High capacity of teamwork
10. Autonomy

Seattle, WA

Persons in these roles are expected to work from our offices in Seattle.

Who You Are:

Are you passionate about AI and its potential to help in the scientific process? We are looking for talented researchers interested in applying their skills towards the next generation of intelligent systems, and pursuing our mission of AI for the common good.

Our team is currently working on exciting, collaborative new projects in the area of intelligent agents and scientific discovery, including: data-driven discovery, AI research assistants for scientists, end-to-end discovery, agents that can continually learn over time, and methods for training agentic models. We are looking for ambitious, motivated researchers ready to take on a complex challenge with huge potential impact for the future of AI, particularly with skills and interest in the following areas:

• Agentic planning, reasoning, and learning
• Automated and AI-assisted scientific discovery
• Learning, representation, and reasoning
• Model tuning and specialization

Who We Are:

The Aristo team at Ai2 has pioneered research in machine reasoning, learning, and explanation for many years, including creating the first system to pass standardized science tests (8th Grade) back in 2019. Since then, we have leveraged language models to create advances in multihop reasoning, explanation, intelligent agents, and learning. Our most recent work is in the area of assisted and automated scientific discovery, an ambitious and exciting integration of all these technologies.

At Ai2, you will be working with world-class AI researchers and talented software engineers. We perform team-based, ambitious research, with a mandate to strive for big breakthroughs, not just incremental progress, in an exciting and interactive workplace.

What You’ll Need:

• You are an energetic, inspired individual with a passion for AI.
• You have a PhD (or are nearing PhD completion) with research experience in Computer Science or related field.
• You have a strong publication record in AI-related areas, in particular in the areas of interest listed above. Example venues include ACL, ICLR, EMNLP, NeurIPS, ICML, and NAACL. Contributions to research communities (e.g. workshop organization, tutorials) are a plus.
• You have strong software engineering skills.

Physical Demands and Work Environment:

• Must be able to remain in a stationary position for long periods of time.
• The ability to communicate information and ideas so others will understand.
• The ability to observe details at close range.

A Little More About Ai2:

The Allen Institute for Artificial Intelligence is a non-profit research institute in Seattle founded by Paul Allen. The core mission of Ai2 is to contribute to humanity through high-impact research in artificial intelligence.

Ai2 is proud to be an Equal Opportunity employer. We do not discriminate based upon race, religion, color, national origin, sex, sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

* indicates a required field

Posted on July 30, 2020

Psychedelic Science Funders Collaborative (PSFC), a 501(c)(3) nonprofit, supports research on and clinical trials of physician-prescribed psychedelic medicines and patient access to these treatments. Emerging research indicates that psychedelics have the potential to be a breakthrough in treating PTSD, depression, addiction, and other conditions. PSFC was born in 2017 out of a realization that psychedelic medicine has the potential to make an enormous impact and has an achievable path to regulatory approval, but has been systemically underfunded. Since PSFC’s founding, we have grown into a community of many of the leading funders of psychedelic medicine supporting organizations at the cutting edge of psychedelic research with funding and expert support.

We operate as a flexible network to:

• Identify and evaluate high-impact funding opportunities in psychedelic medicine
• Provide advisory support to scientists and organizations in the psychedelic field, including expertise in pharmaceutical development, organizational growth, and public communications
• Serve as a resource for philanthropists who have specific interests in psychedelics and are interested in advice and collaboration to amplify collective impact
• Foster community among philanthropists, scientists, and the tireless professionals dedicated to the clinical approval of psychedelic medicine

PSFC has set an audacious goal of raising the philanthropic funding needed to make psychedelic therapy available as a medicine.

As the Director of Scientific Research and Partnerships, you will be responsible for building new partnerships with private and public institutions to establish Psychedelic Centers of Excellence for therapist training and clinical practice of psychedelic-assisted psychotherapies. You will foster personal connections with department chairs and heads of development at major Universities and healthcare institutions across the United States, as well as with donors who support those institutions. You understand how institutions work and are adept at navigating institutional politics and power structures. Additionally, you bring clinical expertise to the PSFC organization with practical experiences in clinical operations to strengthen our due diligence on clinical trial grant proposals.

As the ideal candidate for the role, you are a strategic thinker, a self-starter, and enjoy building and nurturing relationships. Passionate about psychedelic science, you have stellar communication skills and stay up to speed on trends and opportunities in the psychedelic field. And as a member of a small, dynamic organization, you are grounded, direct, clear, kind, and a team player.

Specific responsibilities include the following:

• Devise a partnership strategy to work with medical and academic institutions (e.g. Veterans Affairs Medical Centers, top universities, etc.) to build out psychedelic centers of excellence for clinical practice and training
• Identify and source high-potential institutional prospects through research, strategic outreach, and relationship-building to cultivate new partnerships with academic researchers and institutions
• Build trusted relationships and champion collaboration with stakeholders in psychedelic medicine
• As a grantmaker, evaluate incoming grant proposals and provide due diligence on organizations conducting clinical trials
• Evaluate Investigator Initiated Trials (IITs) on alignment with internal strategic priorities for clinical practice and training
• Introduce IITs to sponsors who may be able to provide scientific input and or drug product
• Connect IITs to sponsors who may be able to provide scientific input and/or drug product
• Build a framework and engagement playbook for clinical partnerships
• Manage tools to maintain a real-time snapshot of relationships and forecast future opportunities
• Coordinate with other members of the PSFC team and handle a portion of our shared administrative tasks

• 5+ years of experience in business development, partnership management, or management consulting
• 5+ years of experience working in the healthcare, medical device, or pharmaceutical industry
• Bachelor’s degree in life sciences (MD, PharmD, biology, bioinformatics, biological engineering or similar)
• Experience with scientific research in a hospital/academic center or innovation office is a plus
• Experienced working on clinical trials and drug development through to FDA approval
• Can balance high-level strategic thinking with hands-on execution
• Are a self-starter and you proactively drive projects toward successful completion
• Able to lead, motivate and understand the needs of others
• Proven ability to work creatively and analytically in a problem-solving environment
• Excellent communication (written and oral) and interpersonal skills
• Willing to travel. Must be willing to travel in the US for partnership meetings and conferences.

The position will be a full-time staff position based in San Francisco. To apply, please submit your application on our website at psfc.co/jobs .

PSFC is an equal opportunity organization and is committed to creating an inclusive environment for all employees free from discrimination on the basis of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, age, sexual orientation, military and veteran status, arrest or conviction record, and any other basis prohibited by law.

Please check your e-mail for a link to activate your account.

100% Onsite

POSITION: Senior Research Associate, Translational Research, Oncology (non-PhD)

DEPARTMENT: Translational Research, Oncogenesis TRC

PREREQUISITES: Bachelor's degree in a scientific discipline with at least 3 years work experience

Summary/Scope:
This Senior Research Associate /Senior Associate Scientist will join the Translational Development team in Oncogenesis Thematic Research Center (TRC) located in San Diego, California. The successful candidate will have a broad understanding of molecular cell biology, immunology, and oncology, with strong expertise in cell-based assay development and biomarker discovery.
The incumbent will be responsible for addressing questions of drug scheduling, supporting patient selection hypothesis, and developing clinical assays using current techniques and primarily in vitro and ex vivo methods; and is responsible for experiment design, execution, and data analysis and report for well-defined projects. The position will require handling and compound treatment of human tissues including whole blood, PBMC, bone marrow aspirates, tumor cell lines, and primary tumors. The incumbent will be expected to maintain an electronic lab notebook and organize results into reports or presentations. The ideal candidate will possess strong communication, writing and record keeping, and presentation skills. The successful candidate will have a proven technical and scientific track record and experience working in a multi-disciplinary team environment.

Responsibilities will include, but are not limited to, the following:

1. Independently execute defined experiments, data analysis and data QC
2. Design and conduct relevant molecular and cell-based assays to support MOA and translational research
3. Analyze and present data in an organized and timely manner
4. Thoughtful review of data and help plan next steps
5. Work at the bench to design and execute established and Client molecular and cell-based assays for translational research
6. Perform cell biology and molecular biology including primary and tumor cell culture, lentiviral transductions, RNA and protein preparation from cells and tissues, qRT-PCR, western blotting, and ELISA. Some training may be provided
7. Hands-on experience in working with CRISPR, siRNA and shRNA is a plus. Training will be provided.
8. May involve handling and processing patient-derived tissues and blood samples
9. Collaborate effectively and cultivate positive and productive relationships with colleagues
10. Participate in maintenance of routine laboratory instrumentation and supplies
11. Adherence to laboratory safety policies and practices

The candidate should:

1. Have a Bachelor's degree in a scientific discipline with at least 3 years work experience
2. Demonstrated proficiency in various molecular and cellular technologies including, but not limited to, sterile cell culture, cell-based assays (CTG, apoptosis), and molecular biology techniques (Protein, DNA and RNA isolations, Western blot, ELISA, qRT-PCR)
3. Proficiency with multi-color flow cytometry techniques and analysis
4. Possess troubleshooting and problem-solving skills to resolve technical questions in a multi-disciplinary environment
5. Experience with high-throughput drug screening is a plus
6. Skilled in Microsoft Office Suite, GraphPad Prism, FlowJo
7. Possess excellent communication, collaboration and organizational skills and attention to detail
8. Ability to work in a fast-paced environment; flexibility to adapt to changes with a positive attitude

CA pay transparency note for CA worker only: The starting hourly compensation for this assignment is a range from $39.37 - $50.00. While the final, individual compensation will be determined by your employer of record (and not Client), factors that will be included in making the final determination may include the characteristics of the assignment, such as demonstrated experience, required skill, and the geographic location where the job is performed. The starting hourly compensation may be subject to change.

Location: SED, WA**Onsite

1. Experience with ELISA**Must Have
2. Western blot, HPLC, PCR
3. Work effectively in a collaborative team setting.
4. Cell culture experience preferred
5. Experience qualifying methods preferred

Design, perform, document and interpret experiments to support analytical development objectives as part of the Vector Release Methods Team. The Vector Release Methods team expands virology knowledge and develops release and characterization analytical methods for viral vectors. Responsibilities include the development, optimization, execution, documentation and transfer of assays.

BS or MS in Biology, Cell Biology, Biochemistry or relevant discipline; (PhD candidates OVERQUALIFIED)

RA 1-3 years of lab experience with ELISA and nucleic acid-based techniques. SRA 3-5 years of lab experience with ELISA and nucleic acid-based techniques. Industrial experience preferred.

1. Thorough understanding of basic protein, chemistry, and molecular biology techniques.
2. Experience with ELISA, Western blot, HPLC, PCR
3. Ability to carefully follow existing methods and SOPs.
4. Outstanding written and oral communication skills.
5. Work effectively in a collaborative team setting.
6. Ability to work in a dynamic environment and balance priorities.
7. Desire to learn and able to follow guidance.

The majority of time in this position will be spent in the laboratory, either sitting or standing. The employee may be required to lift ~20 pounds on rare occasions.

This job description is intended to describe the general nature and level of work being performed by the person assigned to this position. The primary duties and responsibilities are intended to describe those functions that are essential to the performance of this job.

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. There are other duties and responsibilities that are considered incidental or secondary to the overall purpose of this job. Employees holding this position will be required to perform any other job-related duties as requested by management.

Position Handles Hazardous Materials